Polyquaternium-6: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyquaternium-6?

Polyquaternium-6 is a man-made polymer derived from the quaternary ammonium compound dimethyl diallyl ammonium chloride. Through a water-based polymerization process, many of these small molecules are linked together to create a larger, positively charged chain. The result is a clear, water-soluble substance that bonds easily to hair and skin surfaces.

The ingredient first appeared in hair care labs in the 1960s when chemists were looking for a way to cut static and improve comb-through. Its success in shampoos and conditioners quickly led to use in styling gels, leave-in sprays and later in skin care where a light, flexible film was also desirable.

Today Polyquaternium-6 can be spotted in shampoos, conditioners, hair masks, curl creams, setting lotions, styling mousses, body washes, facial cleansers, sheet masks, moisturizers, serums and even some mascaras. It is valued for the slip, smoothness and lightweight hold it gives without feeling greasy.

Polyquaternium-6’s Cosmetic Benefits/Uses

In formulations Polyquaternium-6 delivers two key actions that improve product feel and performance.

  • Antistatic: Its positive charge neutralizes the negative charge that builds up on hair strands or skin, helping to tame flyaways, cut frizz and give a smoother look and feel.
  • Film forming: It lays down a thin, breathable layer that locks in moisture, boosts shine and adds a soft touchable hold. On skin this film can also enhance the spreadability of creams and reduce water loss.

Who Can Use Polyquaternium-6

Polyquaternium-6 is considered friendly to most skin and hair types. Its lightweight film does not add oil so oily or acne-prone skin usually tolerates it well, while its moisture-retaining effect can help those with normal to dry skin feel softer and smoother. Sensitive skin users generally report good comfort because the ingredient has a low irritation profile, though individuals with a known sensitivity to quaternary ammonium compounds may want to proceed with caution.

The polymer is synthetically produced from petrochemical feedstocks with no animal-derived components, making it suitable for vegans and vegetarians.

No published data suggest that Polyquaternium-6 poses a special risk to pregnant or breastfeeding women when used topically in cosmetic concentrations. This is not medical advice and anyone who is expecting or nursing should review all personal care products with a healthcare provider to be safe.

The ingredient is not known to cause photosensitivity so it will not make skin more prone to sunburn. It is also odorless and compatible with most other common cosmetic ingredients which makes formulation conflicts rare.

Potential Side Effects/Adverse Reactions

Reactions to topical Polyquaternium-6 vary from person to person. The following points outline potential side effects that could occur, although they are uncommon when the ingredient is used at normal cosmetic levels.

  • Skin irritation Mild redness or itching can appear in people who have a specific sensitivity to quaternary ammonium compounds
  • Contact dermatitis In rare cases an allergic reaction with rash or hives may develop
  • Scalp buildup Excessive product layers may leave hair feeling heavy or dull until washed out
  • Eye irritation Accidental contact with eyes can cause stinging and watering until rinsed away

If any of these effects occur discontinue use and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5

Polyquaternium-6 is water soluble and does not leave an oily residue that can block pores, which is why it earns a low score of 1. Its lightweight film rinses off easily with regular cleansing, so buildup that might trap sebum or debris is unlikely. This makes it generally suitable for people who are prone to acne or frequent breakouts. The only caveat is that very heavy layering of styling products containing the polymer could mix with other ingredients and create residue that might contribute to congestion if not washed away.

Summary

Polyquaternium-6 works as an antistatic agent and film former. The positive charge in its polymer chain helps neutralize static electricity on hair and skin, cutting frizz and flyaways while giving a smoother feel. At the same time it forms a thin breathable film that locks in moisture boosts shine and provides light flexible hold without greasiness.

Its versatility has kept it a steady fixture in shampoos conditioners styling gels body washes and even some skincare formulas though it is not as buzzworthy as newer naturally derived polymers. Formulators appreciate its reliability ease of use and compatibility with a wide range of ingredients.

Safety data and consumer experience suggest a low risk of irritation or pore clogging for most people. Still it is smart to patch test any new product to rule out personal sensitivities and ensure the product meshes well with your unique skin or scalp.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search