Polyquaternium-60: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyquaternium-60?

Polyquaternium-60 is a synthetic conditioning agent created by reacting a TEA-Diricinoleate/IPDI copolymer with diethyl sulfate. The TEA-Diricinoleate part traces back to castor oil, giving the final polymer a smooth, oily backbone, while IPDI (isophorone diisocyanate) lends strength and flexibility. When the mix is quaternized with diethyl sulfate, the molecule gains a positive charge that lets it cling to hair and skin surfaces.

Chemists first explored quaternary ammonium polymers for hair care in the late 20th century as a way to replace heavier oils and waxes. Polyquaternium-60 emerged in the 1990s as an upgrade that offered lightweight slip without buildup. Today the ingredient is made in closed reactors where the base copolymer is formed, then carefully treated with diethyl sulfate to lock in the cationic sites. After purification it arrives at cosmetic labs as a clear to slightly hazy liquid.

You will most often spot Polyquaternium-60 in rinse-off and leave-on hair products such as shampoos, daily conditioners, deep masks, color-protecting treatments, styling creams, gels and anti-frizz serums. Some skin creams and masks also use it to improve texture and reduce static from synthetic fabrics.

Polyquaternium-60’s Cosmetic Benefits/Uses

In formulas Polyquaternium-60 serves two key roles

  • Antistatic – Its positive charge neutralizes the negative charge that builds up on hair and some fabrics, helping strands lie smoothly, cutting flyaways and making hair easier to comb
  • Hair conditioning – It forms a light, even film over the hair shaft that adds slip, softness and a healthy looking sheen without weighing hair down, which improves manageability and protects against breakage

Who Can Use Polyquaternium-60

Polyquaternium-60 is considered gentle enough for all skin and hair types. Its lightweight film does not clog pores so even acne-prone or oily skin usually tolerates it well, while its smoothing action benefits dry or frizzy hair. Extremely sensitive individuals who react to cationic polymers should proceed cautiously but such cases are rare.

The ingredient is synthesized from castor oil derivatives and other lab-made compounds with no animal sourcing so it is suitable for both vegans and vegetarians.

Current safety data show no reproductive or developmental concerns, which means products containing Polyquaternium-60 are generally viewed as safe for women who are pregnant or breastfeeding. This is not medical advice and anyone expecting or nursing should ask a doctor before adding new personal care items.

Polyquaternium-60 does not absorb UV light or make skin more sensitive to the sun so there is no added risk of photosensitivity.

Potential Side Effects/Adverse Reactions

Responses to topical Polyquaternium-60 differ from person to person. The effects listed below are potential outcomes that most users will not experience when the ingredient is formulated and used properly.

  • Mild skin or scalp irritation – rare redness or itching, more likely with very sensitive skin
  • Allergic contact dermatitis – uncommon rash or swelling in those allergic to quaternary ammonium compounds
  • Eye irritation – stinging or watering if the product accidentally gets into the eyes
  • Hair buildup – occasional limp or heavy feel if used in excess or not rinsed thoroughly, resolved by clarifying shampoo

If any of these reactions occur stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1/5

Polyquaternium-60 is a large, water-soluble polymer that stays mostly on the surface of hair and skin rather than sinking into pores. Its light film rinses away easily so it rarely traps oil or dead cells that could spark breakouts. Because of this low pore-blocking potential it earns a 1 on the comedogenic scale.

Suitable for acne-prone or breakout-prone users in most cases.

As with any cationic conditioner, pairing it with heavy oils or waxes in the same routine could raise the overall clogging risk, so keep the rest of your regimen light if congestion is a concern.

Summary

Polyquaternium-60 works as an antistatic agent and hair conditioner by carrying a positive charge that hugs the negatively charged hair surface, smoothing cuticles and forming a thin protective film that boosts softness shine and manageability without added weight.

While not as famous as silicone giants like dimethicone, it enjoys steady use in shampoos, conditioners, masks and leave-ins aimed at sleek everyday styling.

Current safety data mark it as low risk for irritation, toxicity or environmental harm, making it a reliable pick for most people. Still, trying a small patch first is a smart habit whenever you introduce a new product to your routine.

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