Polyquaternium-68: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyquaternium-68?

Polyquaternium-68 is a man-made polymer created by linking together small building blocks called monomers, specifically 1-ethenyl-2-pyrrolidinone, 1-ethenylimidazole and a quaternized version of ethenylimidazole combined with methyl sulfate. The result is a large, water-soluble molecule that carries a positive charge. This positive charge is why it is grouped under the “polyquaternium” family, which is known for clinging to hair and skin surfaces.

The ingredient grew popular in the 1990s when formulators wanted a lightweight alternative to heavy resins that could hold styles in place without flaking. Advances in polymer chemistry made it possible to fine-tune its size and charge so it forms smooth, flexible films instead of stiff, crunchy layers.

Manufacturing starts with the individual monomers, which are mixed in water. Heat or a gentle catalyst triggers them to join into long chains in a controlled reaction. The finished polymer is purified, dried or kept as a liquid concentrate, then shipped to cosmetic labs.

You will most often find Polyquaternium-68 in hair sprays, styling gels, mousse, curl defining creams and leave-in conditioners. It can also appear in some facial masks or makeup primers that need a thin film to improve wear time.

Polyquaternium-68’s Cosmetic Benefits/Uses

This ingredient earns its spot on labels because it pulls double duty in formulas.

• Film forming: Creates an invisible layer that smooths hair fibers or skin, locking in moisture, reducing frizz and helping other ingredients stay put

• Hair fixing: Provides flexible hold so styles keep their shape yet remain touchable and easy to brush out

Who Can Use Polyquaternium-68

Because it is water soluble and forms a light flexible film, Polyquaternium-68 works well for nearly all skin and hair types including oily, dry, combination and color-treated strands. People with sensitive skin usually tolerate it, though very reactive complexions might notice tightness if multiple film formers are layered in the same routine.

The polymer is synthesized entirely from petrochemical building blocks so no animal-derived substances enter the process, making it suitable for vegans and vegetarians.

Current safety assessments have not flagged Polyquaternium-68 as a risk for pregnant or breastfeeding women when used topically in rinse-off or leave-on products. This is not medical advice; expecting or nursing mothers should discuss any cosmetic regimen with their doctor to be safe.

The ingredient does not increase photosensitivity so there is no special need for extra sun precautions beyond standard daily SPF use.

Potential Side Effects/Adverse Reactions

Individual responses can vary. The issues listed below are possible yet uncommon when Polyquaternium-68 is formulated and used properly.

  • Mild scalp or skin irritation such as redness itching or dryness
  • Product buildup that leaves hair looking dull or feeling heavy if styling products are layered without regular cleansing
  • Allergic contact dermatitis in people already sensitized to quaternary ammonium compounds
  • Eye irritation if sprays or gels accidentally enter the eyes

If you experience any negative reaction while using this ingredient or a product containing it stop use and seek advice from a medical professional.

Comedogenic Rating

Rating: 0. Polyquaternium-68 is a big, water-soluble molecule that sits on the surface then rinses or wears off without seeping into pores or mixing with skin oils. Because it is not oily or waxy it has little chance of blocking follicles, so it is generally safe for acne-prone or breakout-prone skin. No studies or anecdotal reports link it to clogged pores, though product build-up from heavy styling layers can indirectly dull skin if cleansing is skipped.

Summary

Polyquaternium-68 acts as a film former and hair fixer. Its positively charged chains spread into a thin mesh that smooths cuticles, tames frizz, locks in moisture and holds styles while staying flexible. It shows up most in sprays, gels and mousses because formulators value that soft hold without flakes. Though not a headline ingredient like hyaluronic acid its steady performance keeps it in many everyday styling products.

Current safety data label it low risk with only rare irritation reports. When trying any new product it is wise to patch test first to make sure your skin or scalp agrees with the full formula.

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