Polyquaternium-96: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyquaternium-96?

Polyquaternium-96 is a synthetic polymer belonging to the quaternary ammonium family. Chemically, it is produced by polymerizing dimethylaminopropylacrylamide, acrylamide and acrylonitrile, then reacting the resulting chain with methyl chloride to create a permanently charged, water-soluble salt. The positive charge helps it cling to the negatively charged surface of hair and skin, giving the ingredient its smoothing and conditioning abilities.

Developed in the late 1990s as formulators searched for gentle alternatives to older, heavier conditioning agents, Polyquaternium-96 quickly became popular for its lightweight feel and strong film-forming properties. Modern manufacturing relies on controlled batch or continuous polymerization followed by careful purification to remove unreacted monomers, ensuring safety and consistency for cosmetic use.

You will most often spot Polyquaternium-96 in rinse-off and leave-on hair products such as shampoos, conditioners, styling gels, mousses and anti-frizz serums. It also shows up in some facial masks, hydrating toners, light creams and makeup primers where a smooth, flexible film can boost skin feel and wear time.

Polyquaternium-96’s Cosmetic Benefits/Uses

Formulators choose Polyquaternium-96 because it pulls double duty in many products, making them easier to apply and more pleasant to wear.

  • Antistatic: The ingredient’s positive charge neutralizes static build-up on hair strands which helps prevent flyaways and frizz especially in dry or low-humidity environments.
  • Film Forming: It lays down a thin breathable layer that locks in moisture, enhances shine and can extend the longevity of styling or makeup products without a stiff feel.
  • Hair Conditioning: By smoothing the cuticle and binding lightweight moisture to each strand, Polyquaternium-96 leaves hair softer, easier to comb and less prone to breakage.

Who Can Use Polyquaternium-96

Because it is lightweight and water soluble, Polyquaternium-96 suits nearly every skin and hair type including dry, oily, combination and sensitive. Its film is breathable so it rarely clogs pores or weighs hair down. People with a history of allergies to quaternary ammonium compounds should proceed carefully as they may be more prone to irritation, though such cases are uncommon.

The ingredient is entirely synthetic and contains no animal derived materials, so it is considered appropriate for both vegans and vegetarians. Most suppliers also certify that no animal testing is performed during production.

Current safety data show no special risks for pregnancy or breastfeeding when Polyquaternium-96 is used in rinse-off or leave-on cosmetics. Absorption through the skin is minimal. This is not medical advice and pregnant or nursing individuals should still review any product with their doctor.

Polyquaternium-96 does not increase photosensitivity and can be used alongside daytime sun exposure without added risk. It is color safe for dyed hair and compatible with most common skincare actives.

Potential Side Effects/Adverse Reactions

Responses to topical Polyquaternium-96 differ by individual. The effects listed below are possible but not expected for the average user when the ingredient is properly formulated and used as directed.

  • Mild skin or scalp irritation such as redness or itching
  • Allergic contact dermatitis in people already sensitized to quaternary ammonium compounds
  • Transient eye stinging or watering if the product accidentally gets into the eyes
  • Product buildup that leaves hair feeling heavy or dull if very high concentrations are used repeatedly

If any of these reactions occur stop using the product and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0/5 (non-comedogenic)

Polyquaternium-96 is highly water soluble and its large, positively charged molecules tend to stay on the surface rather than sinking into pores. This makes it very unlikely to mix with sebum or create blockages that could trigger whiteheads or blackheads. As a result it earns the lowest possible score on the comedogenic scale.

Suitable for acne-prone and breakout-prone skin.

If a finished product containing Polyquaternium-96 does feel heavy or greasy it is usually because of other richer ingredients in the formula, not the polymer itself.

Summary

Polyquaternium-96 works as an antistatic agent, a flexible film former and a lightweight hair conditioner. Its permanently positive charge helps it bind to negatively charged hair and skin, smoothing cuticles, reducing static and laying down a breathable moisture-holding layer that boosts shine and softness.

The ingredient enjoys solid popularity in shampoos, conditioners and styling products while its use in skincare remains more niche. Consumers appreciate its weightless feel and the way it enhances product spread and wear without greasiness.

Current safety data show low irritation potential, minimal skin absorption and no evidence of comedogenicity, making Polyquaternium-96 a generally safe choice for most people. As with any new cosmetic, it is wise to patch test beforehand to confirm personal compatibility.

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