Polyurethane-2: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyurethane-2?

Polyurethane-2 is a man-made copolymer created from several building blocks: hexylene glycol, neopentyl glycol, adipic acid, saturated methylene diphenyldiisocyanate and dimethylolpropanoic acid. These small molecules link together to form long chains that behave like a flexible plastic film when they dry on the skin. Polyurethane technology was first developed for industrial coatings in the mid-20th century because of its toughness and resistance to water. Formulators later noticed that the same film-forming traits could benefit cosmetics, so lighter cosmetic-grade versions such as Polyurethane-2 were introduced in the 1990s.

To make Polyurethane-2, chemists blend the glycol and acid components with the diisocyanate under controlled heat. The reaction joins them into a stable prepolymer, which is then neutralized with dimethylolpropanoic acid. The result is a water-dispersible resin that can be mixed into creams, gels or sprays without the need for harsh solvents.

You will most often find Polyurethane-2 in products that need a flexible, breathable film on the surface: long-wear foundations, transfer-resistant lipsticks, waterproof mascaras, peel-off face masks, setting sprays, anti-pollution skincare and hair styling products such as gels or smoothing creams.

Polyurethane-2’s Cosmetic Benefits/Uses

In cosmetic formulas Polyurethane-2 serves a single but important purpose.

Film forming: Once the product is applied and the water evaporates, Polyurethane-2 creates an invisible film that helps pigments and active ingredients stay in place, increases water and sweat resistance, reduces smudging and gives the skin or hair a smooth even finish.

Who Can Use Polyurethane-2

Polyurethane-2 is generally suitable for all skin types. Its lightweight breathable film works well on oily skin because it resists excess sebum yet does not feel heavy on dry skin. Combination and normal skin types also benefit from its smoothing effect. Those with very sensitive or eczema-prone skin should watch for irritation from any film-forming polymer, but reports are uncommon.

The ingredient is entirely synthetic, produced from petroleum-derived and mineral raw materials, so it contains no animal by-products. This makes it acceptable for vegans and vegetarians, assuming the finished product has not been animal-tested in regions where that is still required by law.

Current safety assessments show negligible skin penetration, so topical use in pregnancy or while breastfeeding is considered low risk. This is not medical advice and anyone who is pregnant or nursing should run any skincare product they plan to use past a doctor just to be on the safe side.

Polyurethane-2 is not known to cause photosensitivity and does not interact with UV filters, so daytime use is fine as long as normal sun protection habits are followed.

Potential Side Effects/Adverse Reactions

Reactions to topical Polyurethane-2 vary from person to person. The following is a list of potential side effects that could occur, though they are unlikely for most users when the ingredient is properly formulated.

  • Contact irritation – mild redness stinging or itching can appear in people with very reactive skin
  • Allergic contact dermatitis – rare immune response producing rash or swelling
  • Acne flare-ups in extremely acne-prone individuals – the film may trap surface oils leading to clogged pores for a small subset of users
  • Eye discomfort – possible if the ingredient is used in a product that migrates into the eyes such as mascara

If any of these effects occur use should be discontinued and medical advice sought if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5

Polyurethane-2 is a large film-forming polymer that sits on the surface rather than penetrating pores, so it is unlikely to clog them directly. However its breathable film can still trap existing oil or debris if the overall formula is very heavy, so it earns a low but non-zero score.

Most people who are acne-prone should tolerate the ingredient without issues, especially in lightweight products.

If breakouts do occur they are usually related to other occlusive ingredients in the formula or insufficient cleansing at the end of the day.

Summary

Polyurethane-2 is used mainly as a film former. After application and water evaporation it creates a flexible invisible layer that locks pigments in place, boosts water and sweat resistance, smooths texture and helps active ingredients stay where they are needed.

Its popularity is moderate: you will often see it in long-wear foundations, waterproof mascaras, liquid lipsticks and some anti-pollution or hair styling products, but it is far from ubiquitous and many everyday creams or lotions omit it entirely.

Current safety data shows very low skin penetration, minimal irritation potential and no links to hormonal activity, so it is considered safe for regular topical use. As with any new skincare or makeup product it is smart to patch test first to rule out individual sensitivities.

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