Polyurethane Crosspolymer-2: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyurethane Crosspolymer-2?

Polyurethane Crosspolymer-2 is a synthetic polymer created through a multi-step reaction that links smaller molecules into a stable three-dimensional network. The process begins with guanazole, melamine, glyoxal, glyoxylic acid and 2,2-dimethoxyacetaldehyde, which are combined to form a base polymer. This base is then further reacted with a trimethylolpropane / xylylene diisocyanate crosspolymer and finished with cellulose gum. The result is a highly crosslinked structure that behaves like a flexible microscopic mesh when spread on skin.

Polymers that leave a light film on the skin have been used in cosmetics since the mid-20th century to improve texture and wear time. Polyurethane Crosspolymer-2 is part of a newer generation designed to be lightweight, breathable and compatible with modern clean-beauty expectations. Manufacturers introduced it to the market in the past decade to meet the demand for smoother, longer-lasting makeup and skincare formulas without a heavy feel.

You will commonly find Polyurethane Crosspolymer-2 in primers, foundations, BB creams, sheet masks, leave-on moisturizers and anti-aging serums. Because it forms a thin flexible layer, it helps these products glide on evenly and stay put while still allowing skin to move naturally.

Polyurethane Crosspolymer-2’s Cosmetic Benefits/Uses

In topical products Polyurethane Crosspolymer-2 serves one key purpose that leads to several user-friendly advantages.

Film forming: Once applied the polymer sets into an invisible film that smooths the skin surface, locks other active ingredients in place and enhances product longevity. This film minimizes smudging in color cosmetics, boosts the perceived softness of skin in moisturizers and can help create a subtle blurring effect that visually reduces fine lines and pores.

Who Can Use Polyurethane Crosspolymer-2

Polyurethane Crosspolymer-2 is considered suitable for most skin types including normal, dry, oily and combination because it is an inert film former that sits on the surface rather than penetrating deeply. Sensitive skin can usually tolerate it as well since it contains no known fragrance or dye irritants, though anyone highly reactive to synthetic polymers should proceed cautiously. The ingredient is non-pore-clogging for the vast majority of users so acne-prone skin typically fares well, but very heavy or occlusive formulas that include it could still feel too rich for some blemish-prone individuals.

The compound is produced entirely from laboratory-synthesized raw materials and contains no animal derivatives, making it appropriate for vegans and vegetarians. Its manufacturing process does not rely on animal testing in regions that follow modern cruelty-free standards, though consumers may wish to verify the final product’s certification with each brand.

Current safety data do not flag Polyurethane Crosspolymer-2 as a concern for women who are pregnant or breastfeeding. Because hormonal changes can make skin more reactive, these users should still check with a qualified healthcare provider before adding any new cosmetic product just to be safe. This information is educational and not a substitute for medical advice.

The ingredient does not cause photosensitivity and will not increase the skin’s vulnerability to sunburn. It is chemically stable under UV light and can even help keep sunscreen actives in place by forming a flexible lattice over the skin. No other special lifestyle considerations are known at this time.

Potential Side Effects/Adverse Reactions

Reactions to topical Polyurethane Crosspolymer-2 vary from person to person. The issues listed below are potential side effects and remain uncommon when the ingredient is correctly formulated and used at typical concentrations.

  • Mild skin irritation
  • Redness or itching from rare allergic contact dermatitis
  • Temporary clogged pores if paired with very rich emollients
  • Pilling or flaking when layered over incompatible products
  • Eye irritation if the product migrates into the ocular area

If any discomfort or adverse reaction occurs discontinue use and consult a medical professional for personalized guidance.

Comedogenic Rating

Rating: 1/5

Polyurethane Crosspolymer-2 forms a thin breathable film that sits on top of the skin rather than sinking into pores, so it has very low clogging potential. It is not an oil or fatty ester and does not provide a food source for acne bacteria, which keeps the risk minimal. Most people prone to breakouts can use it without issues, though the overall formula and how heavily it is layered still matter. If the ingredient is blended with rich butters or waxes in a product, the finished item could feel heavier even though the polymer itself is almost non-comedogenic.

Summary

Polyurethane Crosspolymer-2 is mainly a film former that lays down a flexible mesh on the skin. This mesh locks other ingredients in place, smooths texture and helps makeup or skincare wear longer without feeling tight or sticky. Because it is lightweight and chemically stable, brands reach for it when they want a modern silky finish that holds up throughout the day.

While useful, it is not yet a household name. You will see it most often in newer primers and long-wear foundation lines rather than in classic skincare staples, but its presence is growing as formulators look for cleaner alternatives to heavier silicones.

Current research shows the ingredient is safe for topical use with a low risk of irritation or pore blockage. As with any cosmetic, try a small patch first to confirm your individual tolerance then enjoy the smoother feel it can bring to your routine.

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