Potassium Myristoyl Hydrolyzed Collagen: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Potassium Myristoyl Hydrolyzed Collagen?

Potassium Myristoyl Hydrolyzed Collagen is a specialty form of collagen that has been broken down into smaller peptide fragments then coupled with myristic acid and neutralized with potassium. Collagen usually comes from animal connective tissues but once it is hydrolyzed its large protein chains are shortened, allowing better solubility in water-based formulas. The attachment of myristic acid, a fatty acid found in coconut and nutmeg oils, gives the peptide a mild surfactant character while the potassium salt form helps it stay stable and easy to blend.

Chemists began exploring collagen derivatives in the late 20th century as consumers started looking for gentler alternatives to harsh detergents in shampoos and face washes. By pairing hydrolyzed collagen with fatty acids they created ingredients that could clean and condition in a single step. Potassium Myristoyl Hydrolyzed Collagen gained traction during the clean beauty movement since it is viewed as a naturally derived, skin-friendly option.

The manufacturing process involves first hydrolyzing collagen with enzymes or acid, reacting the resulting peptides with myristic anhydride to form the myristoyl derivative, then neutralizing the mixture with potassium hydroxide. After filtration and drying the finished powder dissolves readily in water and shows a slight amphiphilic nature, meaning part of the molecule likes oil and part likes water.

You will often spot this ingredient in sulfate-free shampoos, 2-in-1 conditioners, gentle facial cleansers, micellar waters, sheet masks, leave-on hair treatments, hand creams, anti-aging moisturizers and even in some makeup primers where it helps the product glide smoothly.

Potassium Myristoyl Hydrolyzed Collagen’s Cosmetic Benefits/Uses

Formulators turn to this multitasking peptide because it nurtures both hair and skin while keeping textures light and pleasant.

  • Hair conditioning: The peptide backbone can cling to damaged sites along the hair shaft, laying down a lightweight film that improves softness and combability without weighing strands down. The myristoyl portion adds subtle lubrication that boosts shine and reduces static
  • Skin conditioning: On skin the ingredient forms a breathable, moisture-holding layer that smooths rough patches and leaves a silky after-feel. Its mild surfactant properties also help cleanse without stripping the natural lipid barrier which makes it ideal for sensitive or mature skin

Who Can Use Potassium Myristoyl Hydrolyzed Collagen

This ingredient is generally well tolerated by most skin types, including dry, normal, combination and oily skin. Its lightweight film forming nature makes it especially comforting for dry or mature skin while its non greasy feel keeps it from overwhelming oilier complexions. Sensitive skin usually handles it well because the peptide surfactant is mild and unlikely to disrupt the barrier, though individual tolerance can still vary.

Potassium Myristoyl Hydrolyzed Collagen is derived from animal collagen so it is not suitable for vegans or strict vegetarians. Unless a brand clearly states that it uses a plant or synthetic collagen alternative consumers following a vegan lifestyle will want to avoid it.

Current data shows no specific risks for pregnant or breastfeeding women when the ingredient is used topically at the low levels found in cosmetics. Still this is not medical advice and anyone who is pregnant or nursing should discuss any new skincare product with a qualified healthcare provider before use.

The molecule does not make skin more sensitive to the sun so there is no added risk of photosensitivity. It also plays well with common actives like niacinamide vitamin C and hyaluronic acid, making it easy to slot into most routines.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Potassium Myristoyl Hydrolyzed Collagen can vary from person to person. The points below list potential issues yet they are uncommon for most users when the ingredient is correctly formulated.

  • Redness or mild irritation
  • Itching or tightness if skin is extremely protein sensitive
  • Allergic contact dermatitis in individuals with a collagen allergy
  • Build up on very fine hair leading to slight limpness or residue

If any discomfort or unexpected reaction occurs discontinue use and consult a medical professional for guidance

Comedogenic Rating

Rating: 1/5. Even though the molecule carries a myristic fatty chain, it is bound to short water-soluble collagen peptides and further neutralized as a potassium salt, making it disperse easily in water rather than sitting on the skin like heavier oils. It forms a very thin, breathable film that rinses clean, so it is unlikely to clog pores for most people. In practical use it suits acne-prone or breakout-prone skin, provided the overall formula is also lightweight.

Because it can help detergents feel milder, Potassium Myristoyl Hydrolyzed Collagen often appears alongside other gentle surfactants; if those co-ingredients are fatty or occlusive, the finished product’s pore-clogging potential will depend on the full formula, not on this single component.

Summary

Potassium Myristoyl Hydrolyzed Collagen works as a dual hair and skin conditioner. The collagen peptides latch onto damaged keratin or rough skin spots, while the myristoyl tail adds slip and a soft, moisturized feel. Its mild surfactant nature lets cleansers remove dirt without stripping, and in leave-on formulas it creates a lightweight barrier that holds water in.

Although not as famous as hyaluronic acid or classic hydrolyzed collagen, this ingredient has carved a niche in sulfate-free shampoos, gentle face washes and some anti-aging creams thanks to its clean beauty appeal and multitasking profile.

Topical use is considered very safe with low irritation and low comedogenicity, yet skin is personal so it is always smart to patch test any new product containing Potassium Myristoyl Hydrolyzed Collagen before fully adding it to your routine.

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