Ppg-12-Buteth-12: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Ppg-12-Buteth-12?

Ppg-12-Buteth-12 is a synthetic ingredient made by linking together small units of propylene oxide and ethylene oxide, then capping one end with a butyl group. Chemically, it belongs to a family of substances called polyether glycols, which are valued for their smooth, silky feel. The ingredient was first developed when chemists looked for gentle surfactants and conditioners that could replace heavier oils without leaving a greasy film. Over time its mildness, stability and ease of manufacture made it a favorite in modern personal care labs.

Production starts with propylene oxide reacting in a controlled setting to form a short chain of twelve repeating units. Ethylene oxide is then added in a similar way, also in a block of twelve. A single butyl group is attached at one end to balance the molecule’s water-loving and oil-loving parts. The result is a clear, low-odor liquid that mixes easily with both water and oils, helping blends stay uniform.

You will often spot Ppg-12-Buteth-12 in lightweight leave-in conditioners, rinse-off shampoos, co-wash formulas, sheet masks, facial moisturizers, after-shave balms and light anti-aging serums. Its flexible nature lets product makers use it in sprays, lotions, gels or creams whenever they want a soft finish without clogging pores.

Ppg-12-Buteth-12’s Cosmetic Benefits/Uses

This multitasker supports both hair and skin care products in several helpful ways.

  • Hair conditioning: It coats strands with a thin, breathable layer that makes them feel softer and easier to comb, reducing static and frizz while adding a mild shine.
  • Skin conditioning: It forms a light film on the skin that locks in moisture, leaves a silky touch and boosts the spreadability of other active ingredients for an even application.

Who Can Use Ppg-12-Buteth-12

This lightweight polyether suits most skin types including oily, combination, normal and mildly dry complexions because it delivers slip and softness without a heavy occlusive feel. Those with very dry or compromised barriers may need richer emollients alongside it, while highly reactive or fragrance-sensitive skin should still scan the full formula for other triggers even though Ppg-12-Buteth-12 itself is considered low risk.

The ingredient is produced entirely from petrochemical feedstocks so it contains no animal-derived components, which makes it acceptable for both vegans and vegetarians. As always, final product status depends on the brand’s broader animal testing policies.

Current safety assessments have not flagged Ppg-12-Buteth-12 as a concern for women who are pregnant or breastfeeding when used in rinse-off or leave-on cosmetics. Its large molecular size limits skin penetration and it is not known to interfere hormonally. That said this is not medical advice; expecting or nursing mothers should review any skincare routine with their physician for personalized guidance.

The molecule does not absorb UV light and is not known to make skin more sensitive to sunlight, so it does not increase the risk of sunburn or hyperpigmentation. It is also color-safe for chemically treated hair and is fragrance-free in its raw form, which can be helpful for users avoiding added scent.

Potential Side Effects/Adverse Reactions

Individual responses to topical Ppg-12-Buteth-12 can differ. The points below outline potential effects that could occur in isolated cases, but most people will not experience them when the ingredient is used at the levels typically found in finished products.

  • Mild skin irritation slight redness or stinging may occur on very sensitive or broken skin
  • Contact allergy rare allergic dermatitis marked by itching or small bumps
  • Eye irritation tearing or discomfort if the raw ingredient or a high-concentration product accidentally enters the eyes
  • Scalp buildup a coated feel or limp hair if heavily layered without adequate cleansing

If any of these reactions appear stop using the product immediately and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 1 out of 5

Ppg-12-Buteth-12 is water soluble and forms only a very thin breathable film so it does not trap heavy oils or dead skin in pores. Its large molecular size keeps it mostly on the surface which lessens the chance of clogging. For these reasons it earns a low score of 1.

This makes the ingredient generally fine for people who are prone to acne or breakouts.

No published data suggest it worsens fungal acne and it rinses away easily with standard cleansers which further reduces buildup risk.

Summary

Ppg-12-Buteth-12 works as a light hair and skin conditioner. On hair it smooths the cuticle adds slip and cuts static. On skin it leaves a silky finish helps water stay put and spreads other ingredients more evenly. It can do this because its structure has both water loving and oil loving parts allowing it to sit neatly on the surface without feeling greasy.

The ingredient is moderately popular. It shows up most in lightweight conditioners serums and gels where a soft non heavy feel is key but it is not as well known as silicone or glycerin alternatives.

Current safety reviews find it non sensitizing non toxic and unlikely to penetrate deeply. Still everyone’s skin is different so it is smart to patch test any new product that lists Ppg-12-Buteth-12 just to be safe.

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