Ppg-12-Peg-65 Lanolin Oil: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Ppg-12-Peg-65 Lanolin Oil?

Ppg-12-Peg-65 Lanolin Oil is a modern twist on traditional lanolin, the fatty material extracted from sheep’s wool after shearing. To make it more versatile and easier to blend into water-based formulas, chemists react raw lanolin with two types of solvents: propylene oxide (giving the Ppg-12 component) and ethylene oxide (giving the Peg-65 component). The numbers show the average number of each unit added, so this ingredient carries 12 propylene oxide and 65 ethylene oxide units on every lanolin molecule. The result is a lightweight, partially water-soluble liquid that spreads well, feels less greasy than plain lanolin and mixes effortlessly into both oils and water.

Lanolin itself has been used in skin and hair care for more than a century thanks to its similarity to the skin’s natural oils. The ethoxylated and propoxylated version first appeared in the 1970s when formulators wanted lanolin’s conditioning power without the heavy, sticky feel. Today the ingredient is produced industrially in closed reactors that carefully control temperature, pressure and the ratio of ethylene oxide and propylene oxide, ensuring a consistent molecular weight and safety profile.

You will most often see Ppg-12-Peg-65 Lanolin Oil in rinse-out and leave-in conditioners, deep-conditioning masks, curl creams, soothing hand creams, body lotions, lip balms, makeup removers, cleansing balms, anti-aging serums and baby-care lotions. Its ability to bridge oil and water makes it popular in both rich creams and lighter emulsions.

Ppg-12-Peg-65 Lanolin Oil’s Cosmetic Benefits/Uses

This ingredient brings several useful properties to personal care formulas:

  • Hair conditioning – coats the hair shaft with a thin flexible film that reduces moisture loss, tames frizz and makes strands feel smooth, flexible and easier to style
  • Emollient – softens and lubricates the skin surface, filling in microscopic cracks so skin feels supple and looks healthier
  • Emulsifying – helps oil and water stay mixed, improving the stability of creams and lotions and giving products a pleasing, uniform texture

Who Can Use Ppg-12-Peg-65 Lanolin Oil

This ingredient suits most skin and hair types, especially normal, dry or textured hair and skin that needs extra softness. Its lighter feel compared with plain lanolin makes it acceptable for combination skin, though very oily or acne-prone users may find it a bit rich if applied in high amounts.

Ppg-12-Peg-65 Lanolin Oil comes from sheep wool so it is not suitable for vegans or strict vegetarians. Those who avoid animal-derived ingredients should look for plant-based emollients instead.

Pregnant or breastfeeding individuals are not known to face specific risks from this ingredient when used topically in cosmetics. That said, this is not medical advice and anyone expecting or nursing should run any new product past a qualified health professional to be extra safe.

The ingredient does not increase photosensitivity and has no documented interactions with sun exposure. It is also fragrance free by nature which can be helpful for fragrance-sensitive users.

Potential Side Effects/Adverse Reactions

Reactions to topical Ppg-12-Peg-65 Lanolin Oil vary from person to person. The effects listed below are only possibilities and are unlikely for the average user when the ingredient is properly formulated.

  • Allergic dermatitis in individuals sensitive to lanolin
  • Mild skin or scalp irritation if used at very high concentrations
  • Clogged pores or breakouts in acne-prone skin when applied to the face
  • Eye stinging if the product accidentally gets into the eyes
  • Build-up on fine hair, leaving it limp, when not rinsed thoroughly

If any discomfort, redness or other negative effect occurs stop using the product and seek advice from a healthcare professional

Comedogenic Rating

Rating: 2 / 5

Ppg-12-Peg-65 Lanolin Oil is less likely to clog pores than raw lanolin because the added propylene oxide and ethylene oxide units make the molecules more water dispersible and reduce their tendency to sit heavily on the skin. Even so its fatty backbone can still trap debris in pores on very oily or blemish-prone skin, which is why it earns a mild rating of 2 rather than 0 or 1.

Most people will not break out when this ingredient is used at typical levels, but those who are highly acne-prone may prefer lighter alternatives or use it only in rinse-off products.

The degree of comedogenicity also depends on the overall formula. When paired with lightweight silicones or rapid-absorbing esters, its pore-clogging potential drops further.

Summary

Ppg-12-Peg-65 Lanolin Oil is a multitasker that conditions hair, softens skin and helps oil and water stay blended. It does this by forming a flexible film over hair and skin, filling in tiny surface gaps, and acting as a built-in emulsifier so creams feel smoother and remain stable.

The ingredient is fairly popular in conditioners, curl creams and rich body lotions, though less so in vegan lines that avoid animal derivatives. Formulators appreciate its ability to deliver lanolin benefits without the heavy drag of raw wool fat.

Safety data show it is well tolerated for topical use with only occasional sensitivity in people allergic to lanolin. As with any new cosmetic we recommend a small patch test first to make sure your skin agrees with it.

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