Ppg-28 Cetyl Ether: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Ppg-28 Cetyl Ether?

Ppg-28 Cetyl Ether is a lab made ingredient that belongs to a family of substances called polyethers. Chemists build it by linking small units of propylene glycol (28 of them, to be exact) and attaching a long cetyl chain made of 16 carbon atoms. The result is a silky liquid or soft wax that spreads easily on skin. It was first explored in the 1980s when formulators looked for lighter, more flexible alternatives to heavy mineral oils.

To make it, manufacturers start with propylene oxide and run it through a controlled reaction that stacks the 28 repeating units. They then cap one end with cetyl alcohol and leave a tiny alcohol group on the other end. This design lets the molecule sit nicely between water loving and oil loving ingredients, so it can improve texture and feel.

You will find Ppg-28 Cetyl Ether in face and body moisturizers, lightweight lotions, anti aging creams, sunscreens, rinse off masks, hair conditioners and even some makeup primers. Its job is mainly to soften skin and leave a smooth, non greasy finish.

Ppg-28 Cetyl Ether’s Cosmetic Benefits/Uses

In formulas this ingredient plays a single but important role.

Skin conditioning: Ppg-28 Cetyl Ether coats the surface of skin with a thin, breathable layer that traps water, making the skin feel softer and more supple. It also helps spread other ingredients evenly, giving products a pleasant, velvety touch without clogging pores or feeling heavy.

Who Can Use Ppg-28 Cetyl Ether

Ppg-28 Cetyl Ether is generally suitable for all skin types. Its lightweight feel works well for oily or combination skin because it does not leave a greasy residue, while its moisture-trapping ability benefits normal and dry skin. Sensitive or reactive skin usually tolerates it, though anyone with a known allergy to propylene glycol derivatives should steer clear.

The ingredient is made in a lab from propylene oxide and cetyl alcohol. Both components can be sourced from petroleum or plant oils, and no animal-derived materials are required, so it is typically considered vegan and vegetarian friendly. If this matters to you, check with the specific brand to confirm the origin of its cetyl alcohol.

No data indicate that Ppg-28 Cetyl Ether poses a risk to pregnant or breastfeeding women when used in topical cosmetics. It has a large molecular size, so it is unlikely to penetrate deeply or enter the bloodstream. This is not medical advice, and anyone who is pregnant or nursing should ask a healthcare provider before adding new skincare products, just to be safe.

The ingredient does not cause photosensitivity, so it will not make skin more prone to sunburn. It also does not interfere with common actives like retinoids or vitamin C, so it can sit comfortably in most routines.

Potential Side Effects/Adverse Reactions

Reactions to the topical use of Ppg-28 Cetyl Ether vary from person to person. The points below list potential side effects, but they are uncommon when the ingredient is used at typical cosmetic levels.

  • Skin irritation – rare stinging, burning or itching, most often in very sensitive skin
  • Redness or rash – mild contact dermatitis can occur in those allergic to propylene glycol derivatives
  • Eye irritation – temporary watering or discomfort if a product containing the ingredient gets into the eyes
  • Breakouts in highly acne-prone skin – unlikely but possible if the formula also contains other pore-clogging ingredients

If any of these effects occur, stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1/5
Ppg-28 Cetyl Ether forms a very light, breathable film that sits on the surface without sealing pores shut. Its large, branched structure keeps it from packing tightly inside follicles, so it is unlikely to trigger blackheads or whiteheads for most users. In laboratory and consumer use reports it rarely shows up as an acne culprit, especially when included at the low levels common in skincare and makeup. It is generally suitable for people who are prone to breakouts, provided the rest of the formula is also non-comedogenic. Very oily skin types may still prefer minimal use if the product contains heavier oils along with it.

Summary

Ppg-28 Cetyl Ether is a lab made skin conditioner that wraps skin in a weightless layer to improve softness and water retention while giving formulas a smooth, velvety glide. It is not the most talked-about ingredient, but formulators reach for it when they want slip and a non-greasy finish without relying on silicone or mineral oil, so it quietly appears in a wide range of moisturizers, sunscreens and primers.

Safety data show a low risk of irritation, allergy or pore clogging when used at normal cosmetic levels, making it a reliable pick for nearly all skin types. Still, everyone’s skin is different, so patch testing any new product that contains Ppg-28 Cetyl Ether is a smart step before full-face use.

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