Propylene Glycol Ceteth-3 Propionate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Propylene Glycol Ceteth-3 Propionate?

Propylene Glycol Ceteth-3 Propionate is a synthetic ingredient made by linking propylene glycol, ethylene oxide units and cetyl alcohol then finishing the chain with propionic acid. The result is a lightweight oily liquid that mixes well with both water and oils.

The compound belongs to a group called ethoxylated fatty esters that chemists began exploring in the 1970s when the beauty industry wanted smoother quick-absorbing moisturizers. Over time its balanced feel and skin friendly profile earned it a spot in everyday personal care lines.

Manufacturing starts with plant derived cetyl alcohol, which reacts with three units of ethylene oxide to form ceteth-3. This part is then joined to propylene glycol and finally esterified with propionic acid. Careful control of temperature and pH keeps the chain length consistent so the finished material stays clear and stable.

You will most often see Propylene Glycol Ceteth-3 Propionate in facial and body moisturizers, primers, cleansing balms, sheet masks, anti-aging serums and after-sun lotions where it adds slip without feeling greasy.

Propylene Glycol Ceteth-3 Propionate’s Cosmetic Benefits/Uses

In formulas this ingredient plays a couple of key roles that help skin feel soft and comfortable

  • Skin conditioning – forms a thin breathable layer that leaves skin feeling smooth and hydrated making the overall product feel more nurturing
  • Emollient – fills in tiny gaps between surface cells so skin feels supple and flexible while reducing rough texture

Who Can Use Propylene Glycol Ceteth-3 Propionate

This ingredient suits most skin types thanks to its light, non-greasy feel. Dry and mature skin appreciate the smooth emollience while oily or combination skin benefit from its quick absorption that does not leave a heavy film. Sensitive skin generally tolerates it, though anyone prone to reacting to propylene glycol derivatives should proceed with extra care.

Propylene Glycol Ceteth-3 Propionate is typically produced from plant-derived cetyl alcohol and fully synthetic processes, so it is regarded as vegan and vegetarian friendly when no other animal ingredients are present in the finished product.

Current safety data show no special concerns for pregnant or breastfeeding women when the ingredient is used topically in normal cosmetic concentrations. This is not medical advice and anyone who is expecting or nursing should have their doctor review the full ingredient list of any product just to be safe.

The molecule does not make skin more sensitive to sunlight, so it is not considered photosensitizing. It also plays well with common actives like retinoids, vitamin C and exfoliating acids.

Potential Side Effects/Adverse Reactions

Reactions to topical Propylene Glycol Ceteth-3 Propionate differ from person to person. The points below list potential issues, but most users experience none of them when the ingredient is properly formulated and used as directed.

  • Mild irritation or redness, especially on very sensitive skin
  • Transient stinging on freshly exfoliated or compromised skin
  • Contact dermatitis in individuals allergic to propylene glycol derivatives
  • Watery eyes or slight burning if the product accidentally gets into the eyes
  • Folliculitis or small breakouts if layered with heavy occlusive products on acne-prone skin

If any of these effects occur stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5

Propylene Glycol Ceteth-3 Propionate is a light ester that sinks in quickly and does not leave a thick occlusive film, so it has little tendency to clog pores. Its balanced affinity for both water and oil helps it disperse evenly instead of pooling in follicles where breakouts start.

Because the rating is low it is generally considered suitable for acne-prone or breakout-prone skin, especially when used in well-formulated products at typical levels.

Keep in mind that final comedogenicity also depends on the full formula and personal skin factors such as sebum production or concurrent use of heavy occlusives.

Summary

Propylene Glycol Ceteth-3 Propionate works as a skin-conditioning emollient that softens surface cells and gives products a silky slip without greasiness. It performs these jobs by forming a thin breathable layer that fills micro gaps in the stratum corneum while its partial water solubility supports even spreading and quick absorption.

While not the most famous ingredient on store shelves it is a quiet staple in moisturizers, primers and masks where formulators want a light nonsticky finish.

Existing safety data show a low risk profile with only rare irritation or allergy in sensitive users. As with any new skincare product it is wise to do a small patch test before full use to make sure your skin agrees with the complete formula.

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