Propylene Glycol Diisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Propylene Glycol Diisostearate?

Propylene Glycol Diisostearate is an ester created by joining propylene glycol, a small moisture-loving molecule, with isostearic acid, a fatty acid most often sourced from coconut, soybean or other plant oils. The result is a soft, waxy substance that melts at skin temperature and feels smooth rather than greasy. Chemists first explored this ingredient in the mid-20th century when they were searching for lighter substitutes for mineral oil in personal care goods. By the 1970s its silky after-feel and easy spreadability made it a regular addition to everyday creams and makeup.

Manufacturing begins with purified propylene glycol that reacts with two molecules of isostearic acid in a controlled, high-heat process called esterification. The finished material is filtered, cooled and deodorized, leaving a nearly colorless soft solid that blends effortlessly with oils, waxes and silicones found in modern formulas.

You will spot Propylene Glycol Diisostearate in rich body lotions, facial moisturizers, night creams, lipsticks, creamy foundations, cleansing balms, sunscreens and even some hair conditioners where it helps give a luxurious glide.

Propylene Glycol Diisostearate’s Cosmetic Benefits/Uses

In beauty products Propylene Glycol Diisostearate serves a single but important role as an emollient. As an emollient it fills in tiny gaps in the skin’s surface and forms a light breathable layer that leaves skin feeling soft and supple. This cushioning effect improves the texture of thick creams and color cosmetics, making them smoother to apply and less likely to tug or pill.

Who Can Use Propylene Glycol Diisostearate

This silky ester generally suits most skin types. Dry and normal skin benefit most because the ingredient’s emollient film helps reduce moisture loss and softens rough patches. Combination and slightly oily skin can usually tolerate it as well though very oily or acne prone complexions might find the added richness too heavy if used in high amounts. Individuals with a history of reactions to fatty esters should proceed with extra care.

Propylene Glycol Diisostearate is commonly sourced from plant oils and synthetic propylene glycol so it is usually considered vegan and vegetarian friendly. Those following a strict animal-free lifestyle should still verify with the specific brand to confirm no animal derived processing aids were used.

The Cosmetic Ingredient Review panel has assessed the material as safe for use in leave-on and rinse-off products including by pregnant or breastfeeding women. Because personal circumstances vary this is not medical advice and anyone who is expecting or nursing should show the full ingredient list of any product to their healthcare provider for added reassurance.

The ingredient does not make skin more sensitive to sunlight and has no known interactions with UV filters or self-tanners.

Potential Side Effects/Adverse Reactions

Responses to topical Propylene Glycol Diisostearate differ from person to person. The points below outline potential side effects yet these outcomes are uncommon when the ingredient is used at typical cosmetic levels.

  • Mild skin irritation such as redness stinging or itching
  • Allergic contact dermatitis in individuals already sensitized to fatty alcohols or esters
  • Temporary clogged pores or breakouts in those highly prone to comedones when the ingredient appears high on an oily formula’s list
  • Eye irritation if the product accidentally migrates into the eyes

If any unwanted reaction occurs discontinue use and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 2/5. Propylene Glycol Diisostearate is a bulky fatty ester that sits on skin to smooth and soften but its molecular size limits how deeply it can lodge in pores. Compared with lighter esters such as isopropyl myristate or isopropyl isostearate (both higher on the comedogenic scale) it is less likely to promote blackheads, yet its fatty backbone still carries some pore-clogging potential when used at high levels in rich formulas. Overall it is usually fine for combination or mildly oily skin though people who break out easily should keep an eye on where it sits in the ingredient list and how their skin responds. Extra note: the ingredient’s low melting point means it softens on contact with skin rather than hardening inside pores, another reason its clogging risk remains moderate rather than high.

Summary

Propylene Glycol Diisostearate is primarily an emollient that fills tiny surface gaps and forms a flexible, velvety film so creams glide on evenly and leave skin feeling cushioned. This same property improves spreadability in makeup, helps pigments lay down smoothly and adds a touch of richness to cleansing balms and conditioners. While not a blockbuster name, formulators like it as a lighter alternative to heavier oils and as a texture booster that plays nicely with silicones and natural butters.

Safety assessments by the Cosmetic Ingredient Review panel conclude it is safe for use in both rinse-off and leave-on products, including during pregnancy and lactation, with only rare reports of irritation or allergy. As with any new cosmetic we recommend a simple patch test first so you can be sure the product suits your unique skin.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search