Propylene Glycol Myristate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Propylene Glycol Myristate?

Propylene Glycol Myristate is an ester formed when myristic acid, a saturated fatty acid naturally present in coconut oil palm kernel oil and nutmeg, reacts with propylene glycol, a small organic alcohol. The result is a lightweight oil-like liquid that combines the slip of a fatty acid with the water-compatible nature of propylene glycol, making it particularly versatile for cosmetic use.

The ingredient first appeared in personal care formulas in the early 1970s when chemists were searching for alternatives to heavier vegetable oils that could improve skin feel without leaving a greasy after-touch. By fine-tuning temperature and catalyst conditions during an esterification process, manufacturers consistently create high-purity Propylene Glycol Myristate for modern formulations.

You will often spot it on ingredient lists for cleansers, makeup removers, micellar waters, moisturizers, sunscreens, leave-on lotions, lip products and lightweight serums where it helps balance texture and overall performance.

Propylene Glycol Myristate’s Cosmetic Benefits/Uses

Formulators reach for Propylene Glycol Myristate because it delivers more than one useful role in a product.

  • Skin conditioning: Its silky, emollient nature softens and smooths the skin surface, improving glide and overall sensorial feel while helping lock in moisture for a supple complexion.
  • Cleansing: The molecule’s dual affinity for oil and water allows it to dissolve makeup, sunscreen and daily grime then rinse away easily, reducing the need for harsh surfactants and supporting a gentle cleanse.

Who Can Use Propylene Glycol Myristate

Propylene Glycol Myristate is generally well tolerated by normal, dry, combination and mature skin thanks to its light emollient feel that does not weigh heavily on the surface. Oily or acne-prone users can often use it too, though very blemish-prone individuals may prefer to monitor how their skin responds since richer emollients can sometimes add to congestion in susceptible pores.

The ingredient is synthetically produced from plant-derived myristic acid and propylene glycol, so it is suitable for vegans and vegetarians. No animal-based raw materials or by-products are involved in its manufacture.

Current safety data shows no specific risks for pregnant or breastfeeding women when Propylene Glycol Myristate is used in normal cosmetic concentrations. This is not medical advice; expectant or nursing mothers should discuss any skincare routine with their doctor to be on the safe side.

Propylene Glycol Myristate does not make skin more sensitive to sunlight, so it is not considered a photosensitiser. As with any topical ingredient, using a daily broad-spectrum sunscreen remains good practice.

Potential Side Effects/Adverse Reactions

Individual responses to Propylene Glycol Myristate can vary. The points below outline potential though uncommon reactions when the ingredient is applied to the skin in finished products. When used at appropriate levels most people will not experience these issues.

  • Mild irritation or redness on very sensitive skin
  • Stinging or burning sensation on compromised or freshly exfoliated skin
  • Clogged pores leading to breakouts in those highly prone to acne
  • Allergic contact dermatitis in rare cases of specific sensitivity

If any unwanted reaction occurs, discontinue use and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Propylene Glycol Myristate has a comedogenic rating of 2 out of 5. The fatty acid part gives it a mild occlusive feel that can linger on the surface and, in very oily skins, add to pore buildup. Yet the propylene glycol end keeps the molecule light and helps it rinse off, so it is far less likely to clog than heavier oils.

Most users, including many who are prone to breakouts, can use products containing this ester without extra pimples. Highly acne prone individuals may still wish to keep an eye on their skin’s response.

Remember that the final product formula, how much is applied and how often you use it matter just as much as the rating of any one ingredient.

Summary

Propylene Glycol Myristate works mainly as a skin conditioner and a mild cleanser. Its oil loving side softens and smooths while holding moisture, and its water friendly side binds to rinse water so makeup and grime wash away with less effort.

It is a quiet workhorse rather than a headline star. You might not see it advertised on the front of a bottle yet it shows up in many lotions, micellar waters, sunscreens and lip products because it improves slip and texture without heaviness.

Safety data classifies it as low risk at the levels used in cosmetics. Most people tolerate it well but every skin is different, so doing a quick patch test with any new product is a smart step before full use.

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