Psilanthus Bengalensis Leaf Cell Culture Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Psilanthus Bengalensis Leaf Cell Culture Extract?

Psilanthus bengalensis is a flowering shrub from the Rubiaceae family, a botanical group that also includes coffee plants. Instead of harvesting large amounts of wild leaves, labs take a tiny piece of healthy leaf tissue and grow it in a sterile nutrient solution. The result is a clean, renewable supply of leaf cells rich in natural compounds such as polyphenols, flavonoids, sugars and small peptides that help support skin health.

Interest in this extract began when researchers looked for sustainable plant actives that deliver consistent quality year round. Cell culture technology offered a way to protect the species while making its skin-supportive molecules available for cosmetics. After the cells multiply, they are collected and gently extracted with water or a mild solvent, then filtered and standardized so every batch meets the same safety and performance standards.

Because it is water based and packed with skin-friendly nutrients, Psilanthus Bengalensis Leaf Cell Culture Extract appears in hydrating serums, anti aging creams, sheet masks, soothing lotions, after-sun gels and targeted eye treatments where formulators want a botanical boost without heavy texture.

Psilanthus Bengalensis Leaf Cell Culture Extract’s Cosmetic Benefits/Uses

This ingredient is prized for one main role in skincare.

Skin Conditioning: The extract supplies lightweight moisture, leaving skin feeling softer and smoother while helping to reduce the look of dryness and rough patches. Its natural antioxidants can also fend off daily environmental stress, which keeps the complexion looking fresh and more even toned.

Who Can Use Psilanthus Bengalensis Leaf Cell Culture Extract

This water based extract is gentle enough for most skin types. Oily and combination skin appreciate its weightless feel, while dry or mature skin benefits from the extra hydration. Sensitive skin users usually tolerate it well because the culture is produced in a sterile environment that cuts down on common plant impurities, though anyone with a known allergy to the Rubiaceae family should proceed with caution.

Because the ingredient is entirely plant derived and produced without animal by-products it is suitable for both vegans and vegetarians.

No specific warnings exist for pregnant or breastfeeding women, but data on this exact plant is limited. This content is not medical advice and anyone expecting or nursing should run new skincare purchases past a healthcare professional to be safe.

The extract does not make skin more vulnerable to sunlight so it is not considered photosensitising. As with any new active it can be layered with most daily products, including vitamin C or retinoids, without known issues.

Potential Side Effects/Adverse Reactions

Side effects from topical Psilanthus Bengalensis Leaf Cell Culture Extract differ from person to person. The following list covers potential reactions only; most users will not experience them when the ingredient is used at cosmetic levels in a properly formulated product.

  • Mild redness or warmth especially on very reactive skin
  • Itching or stinging if the skin barrier is already compromised
  • Allergic contact dermatitis in individuals sensitive to botanical extracts from the Rubiaceae family
  • Rash or hives in rare cases of true plant allergy
  • Eye irritation if the product accidentally gets into the eyes

If any of these reactions occur stop using the product and seek guidance from a qualified healthcare provider or dermatologist.

Comedogenic Rating

Rating: 0 / 5

Psilanthus Bengalensis Leaf Cell Culture Extract is water based and contains largely water soluble nutrients rather than fatty oils or waxes that could clog pores. Its lightweight profile means it sits on the skin without forming an occlusive film, so it is classed as non-comedogenic.

Because of this low rating it is generally suitable for people who are prone to acne or frequent breakouts. Only the overall formula matters; if the extract is blended into a heavy cream with pore-clogging oils the finished product could still trigger congestion.

Summary

Psilanthus Bengalensis Leaf Cell Culture Extract mainly conditions skin by supplying quick hydration, antioxidants and small peptides that smooth texture and guard against daily stress. Grown in controlled cell cultures it offers consistent quality and a sustainable alternative to wild harvesting.

The extract is still a niche ingredient so you will not see it in every product on the shelf, but formulators looking for gentle plant actives are starting to include it in serums, lotions and masks.

Safety data to date show very low risk of irritation or allergy in most users and the ingredient scores a zero on the comedogenic scale. As with any new skincare component it is wise to patch test a fresh product before applying it to the entire face just to be cautious.

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