Quaternium-77: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Quaternium-77?

Quaternium-77 is a quaternary ammonium compound made by reacting fatty acids from plant or animal oils with amine molecules then neutralising the result with ethyl sulfate. The finished ingredient has long carbon chains that come from palmitic and stearic acids, giving it a waxy feel that clings well to hair. It first appeared in salon products during the 1970s when formulators were looking for gentler alternatives to older cationic surfactants. Today manufacturers create it in large stainless-steel reactors where the fatty acids are attached to the amine backbone, purified, blended with ethanol or water and finally dried into a clear viscous liquid. You will most often see Quaternium-77 in rinse-off and leave-in conditioners, anti-frizz serums, hair masks, two-phase detangling sprays, styling creams and some conditioning shampoos.

Quaternium-77’s Cosmetic Benefits/Uses

In hair care formulas Quaternium-77 delivers two main benefits

  • Antistatic: Its positive charge neutralises the negative charge that builds up on hair strands after washing which helps prevent flyaways and static cling so hair looks smoother and behaves better in dry or windy conditions
  • Hair conditioning: The fatty chains coat the cuticle in a thin even layer that improves slip, detangles, boosts softness and adds a light glossy finish without weighing hair down

Who Can Use Quaternium-77

Quaternium-77 is considered gentle enough for all skin and scalp types, including dry, normal and oily. Its conditioning layer is lightweight so it rarely weighs down fine hair or exacerbates oiliness, and it can help soften coarse or chemically treated strands. Individuals with hypersensitive skin should still monitor for any discomfort because cationic ingredients can occasionally trigger irritation in very reactive scalps.

Because the fatty acids used to make Quaternium-77 may be sourced from either plants or animal tallow its suitability for vegans or vegetarians depends on how the supplier obtains those lipids. Anyone who avoids animal-derived ingredients should look for formulas that specify a plant origin or carry a certified vegan logo.

No data suggest that Quaternium-77 poses a specific risk to women who are pregnant or breastfeeding when used in rinse-off or leave-in hair products. That said this is not medical advice and expectant or nursing mothers should show any product they plan to use to their healthcare provider to be sure it fits their personal situation.

The ingredient does not increase photosensitivity so it will not make skin or hair more prone to sunburn. It also has no known interaction with hair color dyes or keratin treatments which makes it a versatile conditioning agent for most routines.

Potential Side Effects/Adverse Reactions

Reactions to topical Quaternium-77 differ from person to person. The points below outline potential side effects which remain uncommon in everyday use when the ingredient is correctly formulated.

  • Mild scalp or skin irritation such as redness itching or a tingling sensation
  • Allergic contact dermatitis in individuals already sensitised to quaternary ammonium compounds
  • Eye stinging or watering if the product accidentally gets into the eyes during application or rinsing
  • Product buildup leaving hair feeling heavy or greasy if used in excess or not rinsed thoroughly

If any discomfort or adverse change appears stop using the product and consult a healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 1 / 5

Quaternium-77 is a large, positively charged molecule that tends to stay on the surface of hair shafts rather than sinking into skin or blocking pores. Most of it is found in rinse off products, and even in leave ins it forms a breathable, lightweight film that is unlikely to trap oil or debris inside follicles. For these reasons it has a very low likelihood of causing comedones.

People who are prone to acne or breakouts can generally use products containing Quaternium-77 without worrying about extra clogging.

If a formula blends this ingredient with heavy oils or waxes the overall product could still feel greasy, so always consider the full ingredient list, not just the presence of Quaternium-77.

Summary

Quaternium-77 works mainly as an antistatic agent and hair conditioner. Its positive charge smooths away static while its long fatty chains lay down a thin, glossy coating that boosts slip, softness and shine. These dual actions make combing easier, reduce frizz and give hair a healthier appearance.

The ingredient sits in the middle of the popularity scale. It shows up in many salon and mass market conditioners, masks and detangling sprays, but it competes with silicones and newer polyquaterniums that sometimes get more attention.

Overall safety data are solid: Quaternium-77 is non sensitising for most users, does not disrupt hormones and is safe in both rinse off and leave in formats at typical use levels. As with any new cosmetic product though, it is wise to perform a quick patch test first to confirm your personal tolerance.

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