Quaternium-97: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Quaternium-97?

Quaternium-97 is a quaternary ammonium compound created by reacting fatty acids, often sourced from plant oils, with specialized nitrogen-based agents. This reaction leaves the molecule with a positive charge that helps it bond to negatively charged hair fibers. First explored by chemists in the late 20th century as a gentler alternative to older conditioning agents, it soon became popular in hair care labs for its smooth finish and light feel. Manufacturing involves controlled quaternization in water or alcohol, followed by filtration and drying to produce a clear to pale-yellow liquid or paste. You will typically see Quaternium-97 in rinse-off and leave-in products such as shampoos, conditioners, hair masks, smoothing creams, curl definers and color-protecting treatments.

Quaternium-97’s Cosmetic Benefits/Uses

This ingredient is prized for its hair conditioning ability. By forming a thin coating on the hair shaft it reduces static, makes strands easier to comb, boosts softness, adds a subtle sheen and can help guard against breakage from brushing or heat styling.

Who Can Use Quaternium-97

Because Quaternium-97 is a lightweight conditioning agent it tends to suit all hair textures from fine to coily and it does not target the scalp in a way that would make it risky for oily or sensitive skin types. People with extremely reactive or allergy-prone skin should still be cautious simply because any quaternary ammonium compound can, in rare cases, trigger irritation.

The raw materials used to make Quaternium-97 are usually fatty acids harvested from coconut or other plant oils so the finished ingredient is typically suitable for vegans and vegetarians. If a brand does not specify plant sourcing it may be worth asking, as animal-derived tallow is a possible but uncommon alternative.

No studies show a specific risk for pregnant or breastfeeding women when Quaternium-97 is used in shampoos or conditioners. Nothing suggests it penetrates deeply enough to reach the bloodstream. That said this is not medical advice and anyone who is pregnant or nursing should run any personal care product past a doctor just to be on the safe side.

Quaternium-97 does not make skin or hair more sensitive to sunlight and there are no special lifestyle precautions beyond normal product use.

Potential Side Effects/Adverse Reactions

Responses to topical Quaternium-97 vary from person to person. The effects below are only potential issues and, when the ingredient is correctly formulated, most users will not notice any problems.

  • Mild scalp or skin irritation – redness, itching or a tingling feeling shortly after application
  • Contact dermatitis – in very rare cases an allergic response that results in rash or hives
  • Eye discomfort – temporary stinging if the product accidentally gets into the eyes during rinsing
  • Build-up on hair – heavy use without adequate cleansing might leave strands feeling weighed down or greasy

If any of these reactions occur discontinue use and consult a healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 1/5. Quaternium-97 is a water-soluble quaternary ammonium compound that tends to stay on the surface of hair rather than sinking into pores. Its molecular size and positive charge limit penetration into facial skin follicles, so it is unlikely to clog pores. The rating is kept at 1 rather than 0 because leave-in stylers that touch the hairline might mix with sebum and, in rare situations, contribute to slight buildup.

Overall this ingredient is considered suitable for people who are prone to acne or breakouts.

Because it is mainly used in rinse-off conditioners and diluted formulas, any residue that could linger on facial skin is usually minimal.

Summary

Quaternium-97 is primarily a hair conditioning agent that smooths the cuticle, reduces static, improves combability and adds a light sheen by forming a thin, positively charged film on each strand. It works by attracting to the negatively charged sites on damaged hair, creating an even surface that feels soft and looks healthy.

While not a household name like silicones or panthenol, it is quietly popular among formulators who need a lightweight, vegan-friendly conditioner that rinses clean yet still leaves hair manageable. You will find it most often in mid- to premium-priced shampoos, daily conditioners and leave-ins aimed at reducing frizz.

Current safety data show Quaternium-97 to be low risk when used at typical cosmetic concentrations, with irritation or allergy being uncommon. As with any new personal care product a simple patch test is wise to check for individual sensitivities before full use.

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