Review: Just How Good Is Essential Fx Acyl-Glutathione Smoothing & Brightening Under-Eye Cream by Perricone MD? I Found Out

Does Perricone MD's Under Eye Treatment actually work? I put it through its paces to find out.
Updated on: September 16, 2025
Share:
Inside this article:

This is not a paid or sponsored review. All opinions are the author's own. Individual experience can vary. If you click on links we provide, we may receive compensation.

Introduction

Perricone MD rarely misses a beat in the quest for firmer brighter skin, so when its latest eye treatment landed on my desk I paid attention. The brand has earned a reputation for pairing serious science with feel good textures that coax even the most skeptical complexion into cooperation.

The mouthful that is Essential Fx Acyl-Glutathione Smoothing & Brightening Under-Eye Cream promises to be a multi-tasking hero in spite of its marathon name. Perricone MD says it melts in like a balm, cushions fragile under-eye skin and promptly softens the look of dark circles, deep wrinkles and sagging thanks to Acyl-Glutathione and a vitamin F blend. In short it vows to protect, replenish and radiate.

I put those claims to the test for a full two weeks using it morning and night to decide if this eye cream lives up to the brand’s glowing praise and if it deserves a spot in your skincare budget.

What is Essential Fx Acyl-Glutathione Smoothing & Brightening Under-Eye Cream?

This product sits firmly in the under eye treatment category, a niche designed to tackle the unique concerns that thinner, more delicate skin under the eyes faces daily. Under eye treatments generally aim to hydrate, soften lines and help reduce the look of darkness that can make us seem more tired than we feel. Perricone MD’s formula approaches those goals with a balm like cream that is lightweight once applied yet intentionally rich in condition-boosting ingredients.

The star actives are Acyl-Glutathione, included to support skin’s own defenses while lessening the look of deep-set wrinkles and creases, and a vitamin F blend that focuses on reinforcing the moisture barrier so skin appears smoother and brighter. Together they form a one-two punch that targets both immediate dryness and the gradual formation of fine lines. The brand also points to a naturally aromatic scent, a reminder that no added perfume is present, which can be a plus for sensitive eyes.

In short, Essential Fx Acyl-Glutathione Smoothing & Brightening Under-Eye Cream is positioned as a multitasking treatment meant to cushion fragile under eye skin, visibly soften dark circles and smooth early or established wrinkles while lending a subtle radiance to the area.

Did it work?

In the name of very serious at-home science I parked my regular eye serum on the bench for three days before starting this test run, giving my under eyes a short break to reset. Fourteen days felt like a fair audition period and I applied a lentil-size dab with my ring finger every morning and evening without fail.

The first impression was all about texture. It melted on contact and left a cushioned veil that never slid into my eyes or competed with concealer. Within the first few minutes the area looked plumper, almost as if tiny cracks had been spackled and lightly blurred. Dark circles, however, only appeared fractionally softer and still needed help from makeup to look fully rested.

By the one-week mark hydration was clearly this cream’s strongest play. I woke up to skin that felt comfortably elastic rather than papery and late-day dryness lines no longer showed up midway through Zoom calls. Fine expression lines looked slightly relaxed, yet deeper crow’s-feet held their ground. The supposed brightening effect registered as a faint luminosity rather than a true lightening of pigmentation.

Day fourteen arrived with incremental but welcome gains. The surface felt smooth and resilient and concealer sat more evenly. I still saw my inherited bluish circles and any lifting of mild under eye sagging was, if present, subtle enough to question. In short the product delivered solid moisturising power and a gentle soft-focus finish but stopped short of the more heroic claims.

So did it work? Partially. It ticks the boxes for comfort, quick absorption and modest line smoothing yet it does not quite rewrite the genetic script of my dark circles or deeper wrinkles. I will finish the pot with pleasure but I will likely return to my usual treatment afterward, keeping this in mind as a reliable hydrator that plays nicely with makeup for days when my eyes need an extra cushion.

Main ingredients explained

The headline active here is Acyl-Glutathione, a lab-stabilised version of the antioxidant your own body makes to defend against oxidative stress. Topically it behaves like a wrinkle relaxer, helping to smooth the look of etched-in creases while lending a little bounce to tired tissue. Supporting that is the so-called Vitamin F blend which is really a cocktail of omega-rich oils from chia, flaxseed and macadamia. These lipids reinforce the skin barrier so water stays in and environmental irritants stay out, a key reason the cream feels so cocooning after only one use.

Humectants and emollients round out the formula. Glycerin draws water into the surface layers, shea butter and hydrogenated vegetable glycerides lock it there and dimethicone creates the silky finish that keeps concealer from gathering. Octyldodecyl neopentanoate may sound intimidating but its role is simply to give slip and help the balm spread without tugging fragile skin.

For those scanning labels for potential pitfalls, shea butter and macadamia oil carry a mild to moderate comedogenic rating. That means they can sometimes block pores on oily or acne-prone areas, though the under eye zone has far fewer sebaceous glands so risk is minimal. The formula is fragrance-free in the traditional sense yet it does have a faint botanical aroma courtesy of rosemary leaf extract and other plant oils.

No animal-derived ingredients appear on the INCI list so vegans and vegetarians can use it with confidence, though Perricone MD itself is not a certified vegan brand. Expecting or nursing mothers should run any new topical past their doctor first; while nothing here is flagged as a high-risk pregnancy ingredient the presence of lactic acid and essential oils warrants the usual caution.

One last note: titanium dioxide and iron oxides lend the cream a soft tint that helps scatter light and create an instant blur, a clever touch that makes the subtle brightening claims feel believable straight out of the gate.

What I liked/didn’t like

After two weeks of twice-daily use here is the quick take.

What works well:

  • Melts in without residue and layers smoothly under makeup so the eye area stays comfortably hydrated all day
  • Fine lines look gently softened and the skin surface feels more elastic after about a week
  • Free of added fragrance and animal-derived ingredients which broadens its appeal for sensitive or vegan users

What to consider:

  • Brightening is mild so persistent hereditary dark circles will still need concealer help
  • Deep wrinkles and visible sagging show only subtle change even with consistent use
  • Rich lipid content may feel overly occlusive for those who prefer a weightless finish, especially in humid climates

My final thoughts

Eye creams are notoriously hard to judge because the results tend to be incremental and depend heavily on genetics, sleep and diet. After two diligent weeks Essential Fx Acyl-Glutathione Smoothing & Brightening Under-Eye Cream earns a solid 8/10 from me. Its comforting texture and reliable hydration make it a dependable daily treatment for anyone whose priorities are suppleness and a gentle blur of fine lines. If your dark circles are more pigmentation than fatigue you will still need concealer backup, and those hoping for a dramatic lift in sagging may find the change too subtle to celebrate. Within that context I would recommend it to friends who already like richer formulas and want an easy partner for makeup, while advising severe darkness or deep wrinkle hunters to temper expectations.

Because no single jar of miracles fits all under eyes I keep a short list of alternatives that I have rotated through. Deascal’s Dark Circle Cream is an excellent all-rounder that brightens the entire eye area and does so at a refreshingly accessible price point. If you lean toward vitamin C based radiance Goodal’s Green Tangerine Vita C Dark Circle Eye Cream delivers a zesty boost without irritation. Caudalie’s Vinoperfect Dark Circle Brightening Eye Cream offers a light whipped feel plus polyphenol antioxidants for those who dislike heavier textures. Finally Kiehl’s Powerful-Strength Line-Reducing & Dark Circle-Diminishing Vitamin C Eye Serum is a slick option for minimalists who prefer a fast-absorbing fluid that tackles tone and texture in one go. Each of these has impressed me in its own way and may suit different priorities or skin types.

Before you dive in a quick public service announcement: patch test any new eye product on the inner arm or just below the ear and wait 24 hours, sorry for sounding like an over-protective parent. Remember too that results stick around only as long as you keep using the formula so consistency is your real secret weapon.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.