What Is Rice Oligopeptide-91 Sh-Polypeptide-1?
Rice Oligopeptide-91 Sh-Polypeptide-1 is a lab-designed peptide that blends two short chains of amino acids, Oligopeptide-91 and Sh-Polypeptide-1, in a single 167-unit sequence. Scientists produce it in rice plants through either a quick, temporary expression system or by inserting a copy of the human gene into the rice DNA so the plant can grow the peptide itself. After harvest the peptide is purified, checked for quality and turned into a water-soluble powder or solution ready for skin care formulas. Because it is made of the same 20 standard amino acids found in our own skin, it is well tolerated and easily incorporated into creams, serums, masks and anti-aging moisturizers. Brands often choose it for products aimed at plumping moisture, smoothing texture and supporting a healthy skin barrier.
Rice Oligopeptide-91 Sh-Polypeptide-1’s Cosmetic Benefits/Uses
This multitasking peptide supports skin feel and appearance in two key ways:
- Humectant: Draws water from the surrounding air and deeper skin layers toward the surface, giving immediate hydration that makes skin look dewy and feel comfortable
- Skin conditioning: Helps improve softness, flexibility and overall smoothness, which can reduce the look of fine lines and leave the complexion more even
Who Can Use Rice Oligopeptide-91 Sh-Polypeptide-1
This peptide is gentle and water based so it suits most skin types including dry, normal, combination, oily and even sensitive skin. Because it is light and non greasy it will not clog pores or leave a heavy film, making it a good option for people who break out easily.
The ingredient is produced in rice plants without any animal derived material, which makes it acceptable for both vegans and vegetarians.
There is no research showing that topical Rice Oligopeptide-91 Sh-Polypeptide-1 poses a risk during pregnancy or while breastfeeding. Still, this is not medical advice and anyone who is pregnant or nursing should check with a doctor before adding new skincare products to a routine.
The peptide does not make skin more sensitive to sunlight so there is no extra photo-sensitivity concern. Regular daytime sun protection is still important for overall skin health.
Potential Side Effects/Adverse Reactions
Reactions to any skincare ingredient can differ from person to person. The points below outline potential side effects but they are uncommon when the product is well formulated and used as directed.
- Mild redness or warmth at the application site
- Temporary itching or tingling as the product absorbs
- Rare allergic contact dermatitis in people sensitive to specific peptides or preservatives in the final formula
- Breakouts if the product pairs the peptide with heavy oils that do not suit acne prone skin
If you notice persistent irritation or any unexpected reaction, stop using the product and consult a healthcare professional.
Comedogenic Rating
Rating: 0 (non-comedogenic)
Rice Oligopeptide-91 Sh-Polypeptide-1 is a small, water-soluble peptide that absorbs quickly and leaves no oily residue, so it does not block pores on its own. Its molecular size and polarity prevent it from sitting in the pore lining where clogs form. For that reason it earns a score of 0.
Suitable for acne-prone and breakout-prone skin.
Keep in mind a finished product’s overall pore-clogging potential depends on the full formula. If the peptide is blended with heavy oils, waxes or rich butters, the product’s comedogenicity could be higher even though the peptide itself stays at 0.
Summary
Rice Oligopeptide-91 Sh-Polypeptide-1 functions mainly as a humectant and skin-conditioning agent. Its chain of 167 amino acids pulls moisture toward the skin surface then helps keep that water in place, leaving skin plump, smooth and comfortable. At the same time the peptide’s amino acid profile supports a flexible stratum corneum so texture looks softer and fine lines appear less noticeable.
The ingredient is still relatively niche compared with well-known hydrators like hyaluronic acid or glycerin, but brands searching for fresh lab-grown actives are starting to use it in specialty serums and moisturizers.
Current data shows it is well tolerated by most skin types with minimal risk of irritation or clogging. As with any new skincare addition be mindful of individual sensitivities and do a quick patch test before full-face use just to stay on the safe side.