Rosa Canina Callus Lysate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Rosa Canina Callus Lysate?

Rosa Canina Callus Lysate is an ingredient made from the cells of dog-rose, a wild rose that grows throughout Europe and parts of Asia. Scientists take a small sample of the plant and grow it in a sterile lab to form a callus, a mass of undifferentiated cells rich in nutrients and active compounds. The cells are then broken open, or lysed, so their contents can be used in skin care. This lysate contains natural antioxidants such as vitamin C derivatives, flavonoids and phenolic acids along with trace amounts of plant pigments that give rose hips their soft pink tint.

The use of plant cell cultures in cosmetics started in the late 1990s as brands looked for sustainable and repeatable ways to tap into botanical benefits without overharvesting wild plants. Because callus cultures grow in a controlled environment they are free from pesticides and seasonal changes, offering consistent quality year round.

After the cells are grown they are filtered, concentrated and sometimes blended with a gentle solvent like glycerin to create a stable raw material that formulators can add to creams, serums and masks. You will often find Rosa Canina Callus Lysate in brightening products, antioxidant serums, anti-aging creams, light moisturizers and makeup items where a hint of rosy color is welcome.

Rosa Canina Callus Lysate’s Cosmetic Benefits/Uses

Rosa Canina Callus Lysate brings two main actions to a formula:

  • Antioxidant – its natural vitamin C derivatives and polyphenols help neutralize free radicals created by sun exposure and pollution which can slow the look of premature aging and boost overall skin radiance
  • Colorant – the gentle pink pigments from the rose cells can give lotions serums or makeup a soft tint reducing the need for synthetic dyes and adding a subtle rosy hue that many users find appealing

Who Can Use Rosa Canina Callus Lysate

Rosa Canina Callus Lysate is gentle enough for most skin types, including dry, normal, combination, oily and mildly sensitive skins, thanks to its low level of acids and fragrance. Those with a confirmed allergy to roses or other members of the Rosaceae family should avoid it, since even purified extracts can trigger a reaction in highly sensitised individuals.

The ingredient is produced entirely from plant cell cultures grown in a sterile medium, with no animal derivatives used in any step, so it is suitable for both vegans and vegetarians.

There are no known hormonal or teratogenic effects linked to topical use, making it generally acceptable during pregnancy and while breastfeeding. This is not medical advice; pregnant or nursing users should show any product they plan to apply to their healthcare provider just to be safe.

Rosa Canina Callus Lysate does not make skin more sensitive to sunlight, so it is not considered photosensitising. Standard daytime sun protection is still recommended as part of a well rounded routine.

Potential Side Effects/Adverse Reactions

Side effects from using Rosa Canina Callus Lysate can vary from person to person. The points below are potential outcomes only and are unlikely for the average user when the ingredient is formulated and used correctly.

  • Mild irritation or stinging in very reactive skin
  • Redness or warmth at the application site, particularly in people allergic to roses
  • Allergic contact dermatitis presenting as itching, bumps or swelling
  • Temporary pink staining of very fair skin if a product contains a high concentration of the natural pigment

If you experience any of these reactions stop using the product and consult a healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 1/5. Rosa Canina Callus Lysate is mostly made up of water-soluble antioxidants and tiny amounts of natural pigment, with virtually no heavy oils or waxes that could clog pores. Because it is produced in a lab and filtered to remove cell debris, the finished material is light and non-greasy. As a result it is generally suitable for people who are prone to acne or breakouts. Formulators often pair it with lightweight gel or serum bases, further lowering any pore-blocking risk.

One point is deducted from a perfect zero because no ingredient can be guaranteed pore-neutral for every single person, especially if it is used in a rich cream together with other comedogenic agents. Still, on its own this lysate is considered very low risk for comedones.

Summary

Rosa Canina Callus Lysate serves mainly as an antioxidant and a gentle colorant. Its vitamin C derivatives, flavonoids and phenolic acids help mop up free radicals created by UV light and pollution, which may slow the look of early aging and keep skin tone brighter. At the same time its trace pink pigments lend a soft rosy tint that can reduce the need for synthetic dyes in creams, serums and even makeup.

The ingredient is gaining traction but is not yet as mainstream as classics like green tea or vitamin C. It tends to show up in niche clean beauty lines and in products that highlight plant cell culture technology.

Overall safety is high. The lysate is vegan, free of common irritants and unlikely to congest pores, with only rare allergic reactions reported in people sensitive to roses. As with any new skincare ingredient it is wise to perform a quick patch test when you first try a product containing Rosa Canina Callus Lysate just to be sure your skin agrees with it.

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