Rubusoside: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Rubusoside?

Rubusoside is a natural sweet glycoside originally isolated from the leaves of the Chinese blackberry plant Viburnum dilatatum, a close relative of raspberries and blackberries. Chemically it is a diterpenoid glycoside known as Kaur-16-en-18-oic acid 13-(beta-D-glucopyranosyloxy) beta-D-glucopyranosyl ester. In simple terms this means it is a plant derived molecule made up of a diterpene backbone linked to two glucose units, giving it water loving properties that are useful in skin care.

The cosmetic industry first took interest in rubusoside in the early 2000s when formulators noticed its ability to hold moisture and create a pleasant skin feel. As clean beauty trends grew, demand for botanically sourced humectants pushed manufacturers to explore this ingredient further. Today it is produced by water extracting the leaves, purifying the sweet fraction, then crystallizing the glycoside through filtration and drying. The result is a fine white powder that dissolves easily in water based formulations.

Rubusoside appears most often in hydrating serums, sheet masks, lightweight moisturizers, soothing gels and anti aging lotions where long lasting moisture without a sticky residue is desired. It can also be found in after sun products and gentle daily creams designed for sensitive skin.

Rubusoside’s Cosmetic Benefits/Uses

When added to topical products rubusoside supports the formula in several ways

  • Humectant: Draws water from the environment and deeper skin layers to the surface helping skin stay plump and hydrated which can soften fine lines and improve overall texture
  • Skin Conditioning: Forms a light protective veil that smooths the skin surface enhancing softness and comfort while boosting the performance of other active ingredients

Who Can Use Rubusoside

Rubusoside’s lightweight water binding nature makes it suitable for most skin types. Dry and dehydrated complexions benefit from its moisture magnet effect while normal and combination skin appreciate the soft non greasy finish. Oily and acne prone users usually tolerate it well because the molecule is small and water soluble so it does not sit heavily on pores. Sensitive skin also tends to respond positively thanks to the lack of fragrance and minimal processing, though any plant derived ingredient can occasionally trigger a reaction in extremely reactive skin.

The ingredient is sourced from blackberry leaves and processed without animal derivatives or animal testing so it aligns with vegan and vegetarian preferences.

No data suggest topical rubusoside poses a risk to pregnant or breastfeeding individuals. Still this is not medical advice and anyone who is pregnant or nursing should run all skincare products past a qualified healthcare provider to be safe.

Rubusoside does not increase photosensitivity and can be used day or night without raising the risk of sun induced irritation. It is also compatible with most common actives, retaining stability across a broad pH range which helps formulators build gentle multi functional products.

Potential Side Effects/Adverse Reactions

Reactions to topical rubusoside vary from person to person. The following are potential side effects that could occur even though they are uncommon when products are well formulated and used as directed.

  • Mild redness or itching in very sensitive or allergy prone skin
  • Transient stickiness if applied in high concentrations or layered with multiple humectants
  • Rare contact dermatitis in individuals specifically allergic to blackberry leaf constituents
  • Enhanced absorption of other actives which could heighten irritation from strong exfoliants or retinoids used in the same routine

If you notice any of these issues discontinue use and consult a dermatologist or healthcare professional for guidance.

Comedogenic Rating

Rating: 0 / 5

Rubusoside is fully water soluble and has a small molecular size so it rinses away easily and does not form an occlusive film that could trap oil or debris inside pores. Because it functions primarily as a humectant rather than an emollient or heavy oil it carries virtually no risk of clogging follicles. This makes it suitable for people who are prone to acne or breakouts.

One point to keep in mind is that its moisture pulling action can slightly enhance penetration of other ingredients in the same formula. If those accompanying actives are comedogenic the overall product could still cause issues even though rubusoside itself does not.

Summary

Rubusoside is a plant derived humectant and skin conditioning agent that draws water into the upper layers of skin then leaves a silky lightweight finish. By binding moisture with its two glucose units it keeps skin plump while smoothing the surface for a softer look and feel.

Although not as famous as hyaluronic acid or glycerin this ingredient has gained quiet popularity in clean beauty products thanks to its natural origin pleasant texture and compatibility with sensitive skin.

Current research and cosmetic usage history suggest it is very safe with minimal risk of irritation or pore blockage. Still it is wise to patch test any new product that contains rubusoside to make sure your skin agrees with the complete formula.

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