What Is S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp?
S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp is a lab-created peptide made up of 53 amino acids. It combines fragments modeled after two research peptides (Hiv-1 Oligopeptide-3 and Oligopeptide-87) that are stabilized with the amino acid lysine. Because it is produced entirely through controlled synthesis rather than animal or plant extraction, it is considered vegan friendly and consistent from batch to batch.
The idea of borrowing sequences from viral research peptides to benefit skin care started in the early 2000s when scientists noticed that certain short chains of amino acids could signal skin cells to perform tasks like repairing or strengthening the surface. Over time, chemists fine-tuned these sequences, removing any biologically risky portions and focusing purely on skin support benefits. The result is a safe cosmetic peptide that mimics helpful cellular signals without carrying any viral material.
Manufacturing begins with automated solid-phase peptide synthesis, where each amino acid is added one by one to build the exact 53-unit chain. After assembly, the peptide is purified through filtration and chromatography, then blended with a cosmetic-grade carrier so it can dissolve smoothly in creams or serums.
You’ll find S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp in targeted products like anti-aging serums, moisturizing creams, overnight masks, concentrated ampoules and post-treatment soothing gels. Formulators favor it when they want a lightweight yet potent active that supports overall skin resilience.
S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp’s Cosmetic Benefits/Uses
This peptide brings several helpful properties to topical formulas.
- Skin conditioning: It helps improve the feel and appearance of the skin by encouraging a smoother texture, better hydration and a more supple surface
- Skin protecting: By reinforcing the skin’s natural barrier it assists in defending against everyday environmental stressors such as pollution and temperature shifts which can lead to dryness or irritation
Who Can Use S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp
This peptide is generally well tolerated by all skin types including dry, oily, combination and sensitive. Because it supports the skin barrier without heavy oils or fragrances it suits acne-prone and redness-prone complexions too. Those with extremely reactive or compromised skin should still introduce it slowly, as they would any new active, to ensure comfort.
S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp is produced entirely through plant-free laboratory synthesis, meaning no animal or insect material is involved. This makes it compatible with vegan and vegetarian lifestyles.
No ingredient components are known to pose issues for women who are pregnant or breastfeeding when applied topically. That said, this is not medical advice and anyone who is expecting or nursing should review new skincare products with their healthcare provider for personal assurance.
The peptide does not increase photosensitivity and can be used day or night. It also plays nicely with most common actives such as niacinamide, hyaluronic acid and non-acidic antioxidants.
Potential Side Effects/Adverse Reactions
Individual responses to topical S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp can vary. The following points outline potential side effects although these outcomes are uncommon when the ingredient is formulated and used correctly.
- Transient redness or warmth
- Mild itching or tingling
- Localized irritation if layered with highly acidic exfoliants or strong retinoids
- Rare allergic contact dermatitis in those sensitive to peptides or preservatives present in the finished product
If discomfort, persistent redness or any other unexpected reaction develops discontinue use and consult a healthcare professional.
Comedogenic Rating
Rating: 0 / 5 (non-comedogenic)
S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp is a large water-soluble peptide that does not clog pores or leave a greasy film on the skin. It lacks thick oils, waxes or silicones that typically raise comedogenicity and is used at very low concentrations, so it earns the lowest rating.
This makes the ingredient suitable for people who are prone to acne or frequent breakouts.
Only the overall product formula can alter its pore-friendliness, so users should still check the full ingredient list of any serum or cream that features this peptide.
Summary
S-Hiv-1 Oligopeptide-3 Sh-Oligopeptide-87 Lysine Sp conditions and protects the skin by mimicking naturally occurring signal peptides. When applied topically it nudges skin cells to reinforce the surface barrier, improve moisture retention and smooth texture, helping the complexion stay resilient against everyday stress.
Right now the peptide sits in the niche world of advanced cosmeceuticals rather than on every drugstore shelf, yet its lab-controlled purity and vegan status are gaining attention among formulators who want reliable high-tech actives.
Safety data show a low risk of irritation or allergy for most users, but everyone’s skin is unique so it is always smart to perform a quick patch test before fully incorporating any new peptide-rich product into a routine.