Saccharomyces Lysate Filtrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Saccharomyces Lysate Filtrate?

Saccharomyces Lysate Filtrate comes from Saccharomyces, a type of yeast widely used in baking and brewing. In a lab setting scientists grow the yeast in a nutrient-rich liquid then break, or lyse, the cells to release their inner goodies. The mix is filtered to remove solid debris, leaving a clear liquid packed with proteins, peptides, amino acids and vitamins. These small molecules are easily absorbed by skin and hair, making the filtrate attractive for beauty formulas.

Interest in yeast-based skincare began in the late 1970s when technicians at a Japanese sake brewery noticed their hands looked unusually smooth and youthful. Researchers traced the effect to fermented yeast extracts and ever since brands have explored different yeast derivatives, including Saccharomyces Lysate Filtrate, for their conditioning and protective qualities.

The ingredient is made through controlled fermentation followed by cell lysis, fine filtration and preservation. Because it is water-based and gentle it slips into many product types without altering texture or scent. You will most often see it in leave-on facial treatments, anti-aging serums, sheet masks, soothing moisturizers, scalp tonics and strengthening hair conditioners.

Saccharomyces Lysate Filtrate’s Cosmetic Benefits/Uses

This multitasking ferment supports both skin and hair performance in a formula.

  • Hair conditioning – the blend of amino acids and peptides coats strands with lightweight moisture, helping to smooth frizz, add softness and improve manageability without heaviness
  • Skin protecting – antioxidants and nutrients form a breathable shield that fights daily environmental stress, supports the skin barrier and promotes a healthier looking complexion

Who Can Use Saccharomyces Lysate Filtrate

Saccharomyces Lysate Filtrate is generally well tolerated by all skin types. Its water-light texture and non-comedogenic profile make it comfortable for oily and acne-prone skin, while the naturally occurring amino acids help dry or mature skin hold on to moisture. Sensitive skin usually does fine with the ingredient because it is low in fragrance and alcohol, although anyone with a known yeast allergy should proceed with caution and consider an alternative.

The filtrate is sourced from yeast, not animals, so it is suitable for vegetarians and vegans. Most suppliers cultivate the yeast in plant-based growth media, yet strict vegans may want to confirm that no animal-derived nutrients were used during fermentation.

Current data shows no specific risks for women who are pregnant or breastfeeding. That said, this information is not medical advice and anyone who is expecting or nursing should review new products with a healthcare professional to be extra safe.

Saccharomyces Lysate Filtrate does not cause photosensitivity, so there is no added need to avoid sunlight beyond normal daily sun protection. It also plays nicely with other common actives such as vitamin C, niacinamide and retinoids, making it easy to slot into an existing routine.

Potential Side Effects/Adverse Reactions

Responses to topical Saccharomyces Lysate Filtrate differ from person to person. The points below outline potential side effects that are possible yet unlikely for most users when the ingredient is included at appropriate levels in a well-formulated product.

  • Irritation or redness – mild stinging or flushing can appear in very reactive skin
  • Allergic contact dermatitis – rare but possible in individuals with a yeast allergy or sensitivity
  • Pustular breakouts – uncommon flare-ups may occur in those prone to fungal-related acne conditions
  • Dryness or tightness – overuse in high concentrations could temporarily upset the skin’s moisture balance

If any of these effects occur discontinue use and consult a qualified healthcare provider or dermatologist for guidance.

Comedogenic Rating

Rating: 0 out of 5. Saccharomyces Lysate Filtrate is a water-based ferment with no pore-clogging oils or waxes, so it sits on skin lightly and rinses away clean. Its small peptides and amino acids absorb without leaving residue that could trap dead cells or sebum. This makes it generally suitable for people prone to acne or breakouts. Keep in mind that the finished product’s overall formula matters; heavy emulsifiers, silicones or butters paired with the filtrate might affect how acne-friendly the final product is.

Summary

Saccharomyces Lysate Filtrate conditions hair and protects skin by delivering a mix of amino acids, peptides, vitamins and antioxidants created during controlled yeast fermentation. These nutrients smooth hair cuticles for softer strands and reinforce the skin barrier against everyday stress, helping the complexion stay calm and hydrated.

The ingredient enjoys moderate popularity, showing up most often in K-beauty serums, sheet masks and lightweight conditioners, though it is less common in mainstream Western lines.

Safety data and user feedback point to a low risk of irritation or allergy for the average person. Even so, everyone’s skin is unique, so doing a quick patch test when trying a new product that contains Saccharomyces Lysate Filtrate is a smart move.

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