Salicyloylhydroxamic Acid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Salicyloylhydroxamic Acid?

Salicyloylhydroxamic Acid is a lab-crafted molecule related to salicylic acid but modified with a hydroxamic group. Its chemical description, Benzamide, N,2-dihydroxy-, hints at two key parts: a salicylate segment that likes to grab onto metals and a hydroxamic section that adds stability. The ingredient was first explored in the late 20th century when formulators searched for gentler ways to keep products fresh without using high levels of traditional preservatives. Today it is produced through a controlled reaction that joins salicylic acid with hydroxylamine, followed by purification to remove any unwanted by-products. You will spot Salicyloylhydroxamic Acid in masks, serums, moisturizers, anti-aging creams and leave-on treatments where brands want to boost formula stability while giving skin a smoother feel.

Salicyloylhydroxamic Acid’s Cosmetic Benefits/Uses

This ingredient serves a couple of useful roles in modern skincare.

  • Chelating: It binds to trace metal ions that can sneak into a formula through water, pigments or packaging. By locking these metals up, it helps prevent color changes, rancid smells and loss of potency so the product stays safe and effective for longer.
  • Skin Conditioning: Beyond its behind-the-scenes work, it lightly softens the skin surface. Regular use can make skin feel smoother and more supple which supports a pleasant product experience.

Who Can Use Salicyloylhydroxamic Acid

Most skin types, including dry, oily, sensitive and combination, can tolerate this ingredient because it is used at low levels and is not acidic like its cousin salicylic acid. Extremely reactive or allergy-prone skin should still approach with caution as with any new cosmetic ingredient. Salicyloylhydroxamic Acid is made entirely in a lab from non-animal sources so it is suitable for vegans and vegetarians. Current data shows no specific risks for women who are pregnant or breastfeeding when the ingredient is used in normal topical amounts, yet this is not medical advice and anyone expecting or nursing should check with a doctor before starting new skincare just to be safe. The molecule does not make skin more sensitive to sunlight so it is not considered a photosensitizer. It also plays well with other common actives like vitamin C or retinol without inactivating them.

Potential Side Effects/Adverse Reactions

Responses to topical Salicyloylhydroxamic Acid differ from person to person. The points below outline possible side effects though most users are unlikely to notice any problems when the ingredient is formulated and used properly.

  • Mild redness or warmth
  • Temporary itching or stinging, especially on broken skin
  • Dryness if blended with many other chelating agents in the same product
  • Rare allergic contact dermatitis resulting in rash or swelling
  • Eye irritation if the product accidentally gets into the eyes

If you experience any of these reactions stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 0/5

Salicyloylhydroxamic Acid is water-soluble and used at very low concentrations, so it does not leave any heavy or greasy residue that could clog pores. Its main job is to bind metal ions, not sit on the skin surface, which keeps the risk of comedone formation virtually nil. Because of this profile it is generally considered safe for acne-prone or breakout-prone skin. No publicly available data link the ingredient to increased sebum production or follicular blockage, and it does not appear on standard lists of pore-clogging substances.

Summary

Salicyloylhydroxamic Acid is a dual-purpose cosmetic helper that chelates stray metal ions to keep formulas stable and conditions skin by giving a light, smooth feel. It performs these roles thanks to its salicylate portion that latches onto metals and its hydroxamic group that maintains the molecule’s grip even in varied pH settings.

The ingredient is still something of a quiet achiever rather than a buzzworthy star, showing up mainly in well-formulated serums masks and moisturizers where brands want an extra layer of preservation without adding traditional preservatives.

Current research and real-world use suggest it is very safe when applied topically, with only rare reports of irritation or allergy. As with any new skincare product it is wise to do a simple patch test before full use to confirm personal compatibility.

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