Scordinine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Scordinine?

Scordinine is a thioglycoside that comes from processed garlic. After garlic cloves are crushed and allowed to age, natural enzymes transform certain sulfur compounds into this stable molecule. Chemically it features a sugar section linked to a sulfur-containing part, a structure that helps it interact gently with skin without the strong odor often linked to raw garlic. Although garlic extracts have appeared in folk beauty rituals for centuries, modern cosmetic chemists isolated Scordinine in the late 1990s while looking for odorless sulfur ingredients with skin-loving effects. Today it is obtained through controlled water-alcohol extraction followed by purification steps that remove pigments, proteins and the characteristic garlic smell, leaving a clear odor-free powder that dissolves easily in water-based formulas.

You will most often spot Scordinine in lightweight moisturizers, soothing masks, anti-aging serums and leave-on treatments aimed at improving overall skin feel.

Scordinine’s Cosmetic Benefits/Uses

Formulators value Scordinine for one main reason

Skin conditioning: It helps soften the skin surface, making it feel smoother and more supple. By binding light moisture to the upper layers it can reduce rough patches and boost the comfortable after-feel of a product, which is why brands add it to hydrators, calming lotions and daily serums.

Who Can Use Scordinine

Scordinine is considered gentle enough for most skin types, from dry to oily and even sensitive, because it conditions without clogging pores or leaving an oily film. People with very reactive skin who often react to botanicals high in sulfur should still proceed with extra care, as its garlic origin can be a trigger for them.

The ingredient is plant derived and processed without animal by-products, so it is suitable for both vegans and vegetarians.

No data points to risks for women who are pregnant or breastfeeding when Scordinine is used in standard cosmetic amounts, yet this is not medical advice. Expectant or nursing mothers should show any product they plan to use to their doctor to be sure it fits their personal situation.

Scordinine is not known to make skin more sensitive to sunlight, so daily use does not require extra sun precautions beyond regular broad-spectrum sunscreen.

Potential Side Effects/Adverse Reactions

Side effects from topical Scordinine can vary from one person to another. The points below cover potential reactions, yet most users will not notice any problems when the ingredient is used at cosmetic levels

  • Mild stinging or burning right after application, usually short-lived
  • Temporary redness, especially on very sensitive or broken skin
  • Localized dryness if layered with strong exfoliants or retinoids
  • Allergic contact dermatitis in people who are allergic to garlic or other allium plants

If any of these effects persist or worsen, stop using the product and consult a healthcare professional for advice.

Comedogenic Rating

Rating: 0 / 5 – Scordinine is a water-soluble molecule with no oily or waxy fractions so it does not build up inside pores or create a film that could block them. Current lab and consumer data show no pore-clogging tendencies even when used in higher test concentrations.

Because of this low risk it is generally considered suitable for skin that is prone to acne or breakouts.

No interactions are reported with common acne treatments like benzoyl peroxide or salicylic acid, which means it can usually be layered without affecting their effectiveness.

Summary

Scordinine’s main role is skin conditioning. By attaching to water molecules it helps keep the outer skin layers moist, leaving them softer and smoother. Its gentle sulfur backbone can also calm minor irritation which further improves skin feel.

The ingredient is still a niche pick, seen mostly in targeted hydration serums and calming lotions rather than mass-market products. Brands that focus on botanical actives often use it to deliver odor-free garlic benefits.

Overall safety data are favorable with only rare reports of irritation linked to garlic allergies. As with any new skincare ingredient it is smart to patch test a small area first to confirm personal compatibility.

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