Sec-Butylphenyl Glyceryl Ether: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sec-Butylphenyl Glyceryl Ether?

Sec-Butylphenyl Glyceryl Ether is a lab-created ingredient that combines a sec-butyl group, a phenyl ring and a glycerin backbone. In simple terms it is a modified form of glycerin where one of the hydrogen atoms is replaced by a sec-butyl-phenyl group. You may also see it listed on labels as Sec-Butylphenoxy Propanediol or Isobutylphenyl Glyceryl Ether.

The compound was first explored in the early 2000s when chemists looked for gentler alternatives to traditional antioxidants found in skin care. By attaching the phenyl ring to glycerin they discovered a molecule that could fight free radicals while still attracting water to the skin. Its cosmetic use grew once formulators realized it could stay stable in both water-based and oil-based products.

Manufacturing starts with glycerin sourced from plant oils. Through a controlled reaction called etherification one hydroxyl group of glycerin is linked to sec-butyl-phenol. The final material is purified and tested for skin compatibility before it reaches cosmetic labs.

Because of its dual action this ingredient turns up in many product types such as lightweight moisturizers, anti-aging serums, after-sun lotions, sheet masks and even some scalp treatments. It fits well in formulas aimed at boosting hydration, reducing the look of fine lines and protecting the skin against daily environmental stress.

Sec-Butylphenyl Glyceryl Ether’s Cosmetic Benefits/Uses

Formulators choose Sec-Butylphenyl Glyceryl Ether for two main reasons

  • Antioxidant: It helps neutralize free radicals produced by UV rays or pollution which can lead to dullness and early signs of aging. Including it in a product supports the skin’s natural defense system and keeps formulas from oxidizing so the texture color and scent stay fresh longer
  • Humectant: The glycerin part of the molecule attracts water from the environment and from deeper skin layers bringing it to the surface. This adds immediate moisture makes skin feel softer and helps smooth fine lines caused by dryness

Who Can Use Sec-Butylphenyl Glyceryl Ether

This ingredient is considered friendly for nearly every skin type. Dry and mature skin enjoy its water-drawing ability while oily and combination skin benefit from light hydration that does not feel greasy. Sensitive skin usually tolerates it well because the molecule is mild and free of common irritants. There are no known reasons for very dry, oily or acne-prone skin to avoid it unless an individual is allergic to phenoxy compounds.

Sec-Butylphenyl Glyceryl Ether is made from plant sourced glycerin and synthetic chemistry, so it is suitable for vegans and vegetarians. No animal by-products or animal testing are involved in its standard supply chain, though finished product policies vary by brand.

Pregnant or breastfeeding women can normally use products containing this ingredient because it is not linked to hormonal effects or vitamin A activity. Still, this is not medical advice and anyone who is expecting or nursing should show the full ingredient list of any skincare product to a health professional before adding it to a routine.

The molecule does not make skin more sensitive to sunlight. Daily sunscreen is still wise for overall skin health but extra precautions are not required specifically because of this ingredient.

Potential Side Effects/Adverse Reactions

Responses to topical Sec-Butylphenyl Glyceryl Ether differ from person to person. The points below cover possible but uncommon reactions when the ingredient is used at normal cosmetic levels in well-made formulas.

  • Mild redness or warmth
  • Temporary stinging on very compromised skin
  • Contact dermatitis in people allergic to phenoxy structures
  • Watery eyes or slight burning if the product accidentally gets into the eye area
  • Rare clogged pores in users extremely prone to congestion

If any of these issues appear stop using the product right away and consult a healthcare professional if symptoms do not calm down quickly.

Comedogenic Rating

Rating: 1 out of 5

Sec-Butylphenyl Glyceryl Ether is built on a glycerin backbone that is water attracting and lightweight. Its molecular size and partial water solubility mean it is unlikely to sit heavily on the skin or block pores. A small chance of congestion exists for people who are extremely prone to clogging, which is why it does not score a perfect 0.

Suitable for acne-prone or breakout-prone skin in most cases.

No published data links this molecule to fungal acne triggers or problematic fatty acids, which further supports its low comedogenic profile.

Summary

Sec-Butylphenyl Glyceryl Ether works as an antioxidant and humectant. The phenyl section donates electrons to neutralize free radicals while the glycerin part pulls water toward the skin surface for softer smoother feel. This dual action helps formulas guard against environmental stress and keep moisture levels balanced.

It is still a niche ingredient seen in newer moisturizers, serums and after-sun products rather than in every mainstream line, yet its blend of stability and skin friendliness is earning it steady attention from formulators.

Overall safety is high with very low irritation or clogging reports. As with any new cosmetic ingredient it is wise to do a quick patch test when trying a fresh product to make sure your individual skin stays comfortable.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search