What Is Sh-Oligopeptide-1 Sr-Ocean Pout Oligopeptide-1 Dipeptide-39?
Sh-Oligopeptide-1 Sr-Ocean Pout Oligopeptide-1 Dipeptide-39 is a lab-engineered protein made through fermentation in the common bacterium E. coli. Scientists fused genetic sequences from human-identical epidermal growth factor, a cold-water fish peptide and a short two-amino-acid fragment to create a single chain with 118 amino acids. During fermentation the bacteria follow this genetic blueprint and release the protein, which is then purified, folded into its active shape and stabilized for skincare use. First explored by biotech researchers looking to mimic the skin’s own repair signals, it entered cosmetic labs in the early 2010s as a gentler alternative to animal-derived growth factors. Today you will usually spot it in anti-aging serums, restorative masks, post-peel soothing gels, barrier-support moisturizers and targeted eye treatments where its peptide nature can shine.
Sh-Oligopeptide-1 Sr-Ocean Pout Oligopeptide-1 Dipeptide-39’s Cosmetic Benefits/Uses
This ingredient is prized for one primary role in cosmetics.
Skin protecting – By supporting the skin’s natural repair signals and fortifying the surface barrier it helps defend against daily environmental stress. Formulators add it to products when they want to reduce visible irritation, improve resilience and maintain a smoother healthier looking complexion.
Who Can Use Sh-Oligopeptide-1 Sr-Ocean Pout Oligopeptide-1 Dipeptide-39
This peptide suits most skin types including dry, oily, combination and sensitive because it focuses on barrier support rather than aggressive exfoliation or strong actives. Extremely reactive or allergy-prone skin should still proceed cautiously since any protein can theoretically trigger sensitivity, but for the average user it is considered gentle.
The ingredient is produced through bacterial fermentation and is not harvested from animals, so it is compatible with vegan and vegetarian lifestyles.
No data suggest specific risks for women who are pregnant or breastfeeding. That said this is not medical advice and anyone expecting or nursing should have a doctor review any skincare product they plan to use just to be safe.
Sh-Oligopeptide-1 Sr-Ocean Pout Oligopeptide-1 Dipeptide-39 does not make skin more prone to sunburn, so photosensitivity is not a concern. It also plays well with most other common cosmetic ingredients, allowing users to layer it alongside moisturizers, antioxidants and sunscreens without special timing rules.
Potential Side Effects/Adverse Reactions
Responses to topical Sh-Oligopeptide-1 Sr-Ocean Pout Oligopeptide-1 Dipeptide-39 vary from person to person. The effects listed below are only potential outcomes and are unlikely for the majority of users when the ingredient is formulated correctly.
- Mild redness or warmth at the application site
- Temporary itching or stinging in very sensitive skin
- Rare allergic reaction marked by hives swelling or rash
- Contact dermatitis if combined with other irritants in the same formula
If any of these reactions occur discontinue use and consult a healthcare professional.
Comedogenic Rating
Rating: 0 / 5
Sh-Oligopeptide-1 Sr-Ocean Pout Oligopeptide-1 Dipeptide-39 is a large water-soluble protein that stays on the skin’s surface and contains no oily or waxy residues, so it has virtually no capacity to block pores. Because it is used at very low percentages in formulas and is typically paired with lightweight carriers, the risk of congestion is minimal.
Suitable for acne-prone or breakout-prone skin.
Do remember the finished product’s overall comedogenicity depends on every ingredient in the formula, not just this peptide.
Summary
Sh-Oligopeptide-1 Sr-Ocean Pout Oligopeptide-1 Dipeptide-39 is a lab-crafted peptide that protects skin by reinforcing the barrier and echoing the skin’s own repair signals. It helps calm visible irritation, boosts resilience and supports a smoother healthier look without exfoliating or sensitising actions.
While not yet a household name, it appears in a growing number of niche anti-aging serums, post-treatment masks and barrier creams as brands seek gentle biotech actives.
Current data and user experience point to a high safety profile with only rare sensitivity issues. As with any new skincare ingredient it is wise to patch test when trying a product that contains this peptide just to be on the safe side.