What Is Sh-Oligopeptide-93?
Sh-Oligopeptide-93, sometimes labeled as MT-4, is a lab-made mini protein built from a short chain of amino acids. Unlike plant oils or mineral powders, this peptide is created through controlled fermentation or solid-phase synthesis, then purified so it is skin-friendly. The idea behind it comes from natural signal peptides found in our own skin that help guide repair and renewal. As researchers learned more about these tiny messengers in the early 2000s, they began crafting stable versions that could sit in a jar without breaking down, giving rise to ingredients like Sh-Oligopeptide-93.
Production starts with a safe strain of bacteria or a resin base that is “taught” the exact amino acid order. Once the chain is built, the peptide is separated, filtered and freeze-dried into a fine powder. Manufacturers then blend this powder into water-based formulas at low percentages to keep it active.
You will most often spot Sh-Oligopeptide-93 in leave-on products that aim to support skin strength such as anti-aging serums, firming creams, sheet masks, eye treatments and post-procedure soothing gels. Its compact size lets it sit close to the skin surface, making it a popular pick when brands want to boost a product’s caring and protective profile without adding heaviness.
Sh-Oligopeptide-93’s Cosmetic Benefits/Uses
In skincare formulas Sh-Oligopeptide-93 takes on several helpful roles that work together to keep skin looking and feeling its best.
- Antioxidant: Helps neutralize everyday stress from pollution and sunlight which can lead to dull tone and early fine lines. By cutting down these stress signals the peptide supports a fresher complexion.
- Skin conditioning: Promotes a smoother touch and softer feel by supporting the skin’s natural renewal rhythm. Regular use can make the surface appear more even and comfortable.
- Skin protecting: Forms a lightweight shield that strengthens the outer barrier so moisture stays in and irritants stay out making it handy for formulas aimed at sensitive or post-treatment skin.
Who Can Use Sh-Oligopeptide-93
This lab made peptide is generally compatible with all major skin types including dry, oily, combination and sensitive. Because it is lightweight and non-greasy it will not clog pores on oily or acne prone skin, while its barrier supporting nature can soothe dryness or sensitivity. There are no known skin types that should automatically avoid it, though anyone with a history of peptide allergies or very reactive skin should stay alert for irritation.
Sh-Oligopeptide-93 is produced through fermentation or solid phase synthesis without animal derived materials so it is suitable for both vegetarians and vegans.
Current research has not flagged any specific risks for pregnant or breastfeeding users. Still this is not medical advice and anyone who is expecting or nursing should clear all new skincare products with a qualified healthcare provider before use.
The peptide does not increase photosensitivity and can be used morning or night. Normal daytime sunscreen habits should be followed regardless.
Potential Side Effects/Adverse Reactions
Responses to topical Sh-Oligopeptide-93 vary from person to person. The points below outline potential reactions only and most users will not experience them when the ingredient is formulated and used correctly.
- Mild temporary redness or warmth
- Light tingling or itching immediately after application
- Localized irritation if layered with strong exfoliating acids or retinoids
- Rare allergic contact dermatitis in individuals sensitive to peptides or preservative systems used alongside the ingredient
If any of these effects occur discontinue use and consult a healthcare professional for guidance.
Comedogenic Rating
Rating: 0 out of 5
Sh-Oligopeptide-93 is a small water-soluble peptide that contains no heavy oils, waxes or fatty alcohols known to block pores. Its lightweight molecular structure sits on the skin surface or absorbs quickly without leaving residue, which is why it earns a solid zero on the comedogenic scale.
Because it does not trap sebum or dead cells, it is considered suitable for people who are prone to acne or frequent breakouts.
Formulas using this peptide may still combine it with other ingredients that rate higher on the scale, so always look at the whole ingredient list if congestion is a concern.
Summary
Sh-Oligopeptide-93 is a lab-crafted mini protein that acts as an antioxidant, skin conditioner and skin protector. It scavenges free radicals to curb dullness, signals the skin to renew itself for a smoother feel and helps reinforce the outer barrier so moisture loss and irritation are kept in check.
While not as famous as powerhouse peptides like Matrixyl, it is appearing more often in modern serums, eye gels and post-procedure creams because brands value its stability and gentle profile.
Current data points to a high safety margin with very low irritation risk, yet skin is personal so it is smart to patch test any new product containing Sh-Oligopeptide-93 before applying it all over the face.