Silene Uralensis Callus Culture Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Silene Uralensis Callus Culture Extract?

Silene Uralensis Callus Culture Extract comes from Silene uralensis, a hardy flowering plant in the Caryophyllaceae family that grows in cold northern regions. Instead of harvesting the whole plant, labs take a small piece of its tissue and grow it in a sterile, nutrient-rich dish to form a callus, a mass of undifferentiated plant cells. From this callus, scientists draw out a concentrated fluid containing protective sugars, polyphenols and natural peptides that the plant uses to survive harsh climates. The controlled indoor process avoids pesticides and seasonal changes, giving a consistent, high-quality extract.

Interest in this extract began when researchers noticed the plant’s ability to resist extreme cold and oxidative stress. As cosmetic brands looked for new plant stem cell ingredients in the early 2000s, Silene uralensis gained attention for its natural defense molecules. Today the extract is made by collecting the callus cells, breaking them apart, then filtering and stabilizing the liquid so it blends smoothly into skincare bases.

You’ll most often see Silene Uralensis Callus Culture Extract in anti-aging serums, daily moisturizers, soothing masks, leave-on hair conditioners and protective day creams where its antioxidant and calming traits can shine.

Silene Uralensis Callus Culture Extract’s Cosmetic Benefits/Uses

This plant-based extract brings several helpful actions to beauty formulas:

  • Antimicrobial – Helps keep products fresher for longer and supports clearer skin by limiting the growth of unwanted surface bacteria
  • Antioxidant – Supplies protective molecules that neutralize free radicals, which can contribute to dullness and early lines, keeping skin looking healthier
  • Hair Conditioning – Forms a light film on strands, adding softness and reducing static so hair feels smoother and easier to manage
  • Skin Protecting – Creates a gentle shield that helps reduce irritation from environmental stressors like wind and pollution while supporting the skin barrier

Who Can Use Silene Uralensis Callus Culture Extract

This gentle plant extract is generally suitable for all skin types including dry, oily, combination, mature and sensitive. It is lightweight and non-greasy so it works well even for easily congested or breakout-prone skin. No specific skin type is considered unsuitable, though anyone with a known allergy to the Caryophyllaceae family should proceed cautiously.

Because the ingredient is obtained from plant cell cultures with no animal-derived agents in the process, products containing Silene Uralensis Callus Culture Extract are appropriate for vegans and vegetarians.

Current research shows no evidence that the extract poses risks during pregnancy or breastfeeding when used topically. That said this is not medical advice and pregnant or nursing individuals should discuss any skincare products with their healthcare provider to be extra safe.

The extract is not known to cause photosensitivity so daytime use does not require extra precautions beyond normal sun protection habits.

Potential Side Effects/Adverse Reactions

Reactions to topical Silene Uralensis Callus Culture Extract vary from person to person. The effects listed below are only potential outcomes and are unlikely for most users when the ingredient is formulated correctly.

  • Temporary redness or mild irritation
  • Stinging or tingling on very sensitive or compromised skin
  • Allergic contact dermatitis in individuals allergic to Silene species or related botanicals
  • Eye irritation if the product accidentally gets into the eyes

If any unwanted reaction occurs stop using the product and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5 Silene Uralensis Callus Culture Extract is water based and light, with no heavy oils or waxes that typically clog pores. Its molecules mostly act on the surface as antioxidants and humectants rather than sinking deeply into sebaceous ducts. Lab tests and available product reviews show little tendency to cause buildup or blackheads on acne prone skin, although individual formulas that contain the extract alongside richer emollients could still pose a risk. In general it is considered suitable for people who are prone to breakouts.

Because comedogenicity can depend on the full product recipe, look at the entire ingredient list if you are extremely congestion sensitive.

Summary

Silene Uralensis Callus Culture Extract delivers four key perks: it curbs microbial growth helping products stay fresh and skin stay clear, neutralizes free radicals with polyphenols to support a youthful look, smooths and softens hair by forming a delicate conditioning film, and bolsters the skin barrier against environmental stress. These benefits stem from the plant’s own survival compounds produced in controlled callus culture, ensuring a steady supply without seasonal swings.

While not yet a household name like aloe or green tea, the extract is quietly gaining traction in niche anti aging and sensitive skin lines that value clean lab grown botanicals. Safety data so far points to a low irritation profile and very low pore clogging risk, making it broadly compatible with most routines. As with any new cosmetic ingredient, it is wise to spot test a small area first to confirm personal tolerance.

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