Sodium Glycinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Glycinate?

Sodium glycinate is the sodium salt of glycine, the simplest amino acid found in proteins. By bonding glycine with a small amount of sodium, chemists create a water-soluble ingredient that blends easily into creams and gels. The compound can be sourced from plant-derived glycine, though most cosmetic-grade material is made in the lab for purity and consistency. It first caught the beauty industry’s attention in the late twentieth century when formulators looked for gentler alternatives to harsher surfactants and conditioning agents. Production is straightforward: glycine is reacted with food-grade sodium hydroxide, then purified and dried into a fine white powder. Thanks to its mild nature, sodium glycinate shows up in a wide range of products such as facial cleansers, micellar waters, sheet masks, hydrating serums, anti-aging moisturizers and soothing after-sun lotions.

Sodium Glycinate’s Cosmetic Benefits/Uses

In skin care formulas sodium glycinate serves one main role: skin conditioning. It helps skin feel smoother and softer by attracting and holding water on the surface, which boosts short-term hydration. It can also calm the feel of cleansers that might otherwise leave skin tight, so products with sodium glycinate often leave a refreshed comfortable finish.

Who Can Use Sodium Glycinate

Sodium glycinate is considered friendly for nearly every skin type. Dry and mature skin appreciate its water-binding effect, while oily or combination skin benefit from its light non-greasy feel. Sensitive skin often tolerates it well because it is mild and has a low chance of causing stinging or redness. There are no known reasons for people with acne-prone skin to avoid it, though those using very potent acne treatments may wish to keep an eye on overall product load to avoid over-layering.

The ingredient is made from glycine and sodium hydroxide, both of which can be sourced without any animal inputs, so it is normally suitable for vegetarians and vegans. Anyone following a strictly plant-based lifestyle can check with the manufacturer to confirm the raw materials are not animal-derived.

Current research shows no specific concerns for pregnant or breastfeeding women when sodium glycinate is applied to the skin. This information is not medical advice. Expectant or nursing mothers should show any skincare product they plan to use to their physician to be on the safe side.

Sodium glycinate does not make skin more sensitive to the sun, so no extra sun precautions are needed beyond daily sunscreen use. It also plays nicely with most common skincare ingredients, which lets formulators slot it into simple or complex routines without conflict.

Potential Side Effects/Adverse Reactions

Side effects from topical use of sodium glycinate can vary between individuals. The points below outline potential reactions but most people will not experience them when the ingredient has been formulated and used correctly.

  • Mild redness or flushing in very reactive skin
  • Transient tingling or warmth when applied over broken or highly irritated skin
  • Rare allergic contact dermatitis marked by itching hives or swelling

If any of these effects occur stop using the product and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Sodium glycinate is a tiny water soluble molecule that has no oily or waxy parts so it does not sit in pores or harden on the skin. It rinses away cleanly and has no record of clogging follicles in lab or real-world testing.

Because of this 0 rating it is generally suitable for people who are prone to acne or frequent breakouts.

Summary

Sodium glycinate’s main job in cosmetics is skin conditioning. It draws water to the skin surface and helps formulas feel smoother which leaves the complexion soft comfortable and balanced. Its mild character also buffers cleansers so they cleanse without a stripped afterfeel.

The ingredient is not a headline superstar but it is quietly popular in gentle cleansers toners masks and lightweight moisturizers where a touch of softness is needed without heaviness.

Safety data show it is well tolerated by most skin types including sensitive and acne prone skin. As with any new skincare product it is wise to run a quick patch test to confirm personal compatibility.

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