Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate?

Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate is a plant-based conditioning and cleansing agent made from grapeseed oil. Chemists start with the light fatty acids found in grapeseed oil, react them with a gentle amino-propyl compound, add dimethyl groups for a positive charge, attach a mild phosphate, then finish the process with a touch of salt to create the final water-friendly powder or liquid. This gives the molecule both oil-loving and water-loving parts so it can coat hair or skin while still rinsing clean.

The ingredient first gained attention in the late 2000s when formulators searched for greener swaps for older quaternary ammonium conditioners. Grapeseed oil offered a renewable source with a pleasant sustainability story. Over time, labs fine-tuned the process to lower irritation potential and improve biodegradability, making it a go-to choice in many modern rinse-off and leave-on products.

You will spot Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate in everyday shampoos, 2-in-1 conditioner cleansers, leave-in sprays, curl creams, body washes, facial cleansers, sheet masks, lightweight moisturizers and after-shave balms.

Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate’s Cosmetic Benefits/Uses

This versatile ingredient offers several perks in one easy-to-use form.

  • Hair conditioning: Deposits a thin, smooth film along the hair shaft that tames frizz, boosts slip, speeds detangling and adds a soft touch without heavy buildup
  • Skin conditioning: Leaves a light breathable layer on the skin surface that helps hold moisture, reduces tightness after cleansing and gives a silky after-feel
  • Cleansing: Because it has both positive and negative sites, it can attract dirt and oil while staying gentle so formulas foam mildly, rinse clean and feel less stripping than strong sulfates

Who Can Use Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate

This ingredient is gentle enough for most skin types including oily, combination, normal and mildly dry skin. Its lightweight film does not clog pores so acne-prone users usually tolerate it well. Extremely dry or eczema-prone skin may need richer occlusives alongside it because the ingredient itself is more of a light conditioner than a heavy barrier booster.

Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate is made from plant oils and contains no animal-derived materials so it is suitable for vegans and vegetarians.

No data show specific risks for pregnant or breastfeeding women when the ingredient is used topically at cosmetic levels. This is informational only and not medical advice, and anyone who is pregnant or nursing should discuss new products with a healthcare provider before use to be extra safe.

The molecule does not make skin more sensitive to sunlight so it is not considered a photosensitizer. It also plays nicely with common actives such as vitamin C, niacinamide and mild exfoliating acids.

Potential Side Effects/Adverse Reactions

Reactions to topical Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate differ from person to person. The following are potential side effects that could occur, though they are uncommon when the ingredient is properly formulated and used in standard amounts

  • Mild skin redness or warmth
  • Itching or transient stinging on very sensitive skin
  • Watery eyes if shampoo or cleanser accidentally gets into the eyes
  • Rare allergic contact dermatitis in individuals allergic to quaternary ammonium compounds

If irritation or any adverse reaction occurs stop using the product and consult a medical professional.

Comedogenic Rating

Rating: 1/5

Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate is highly water dispersible, deposits only a micro-thin layer and is used at low percentages. The grapeseed-derived chains are mostly unsaturated, which are less likely to harden inside pores than heavier saturated fats, so the chance of clogging is minimal.

Generally considered suitable for acne-prone or breakout-prone skin.

Very rich leave-on formulas that pair it with thick oils or waxes could still feel heavy, so overall formulation matters.

Summary

Sodium Grapeseedamidopropyl Pg-Dimonium Chloride Phosphate conditions hair, softens skin and aids gentle cleansing thanks to its balanced oil-friendly and water-friendly structure that leaves a smooth finish yet rinses away clean.

The ingredient is gaining popularity as brands shift toward plant-based quats, though it remains a niche pick compared with long-standing conditioning agents.

Studies and in-market use point to a low irritation profile and no major health concerns at cosmetic levels. As with any new product it is wise to patch test first to make sure your own skin plays nicely with it.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search