Sodium Hydrolyzed Casein: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Hydrolyzed Casein?

Sodium Hydrolyzed Casein is a milk-derived ingredient created when casein, the main protein in cow’s milk, is broken down into smaller pieces called peptides then neutralized with sodium to form a water-soluble powder. This process, known as enzymatic hydrolysis, makes the protein fragments smaller so they can more easily mix with water-based creams and lotions.

Casein hydrolysates first gained attention in the food industry for their digestibility, but formulators soon noticed the peptide-rich material had a smooth, conditioning feel on skin and hair. By the late 20th century it started appearing in salon hair masks and premium face creams, and today it is a regular feature in both mass-market and professional beauty lines.

Manufacturing begins with food-grade casein that is purified, blended with water and enzymes, gently heated, filtered to remove any remaining large proteins, then treated with a sodium solution to stabilize the peptides. The liquid is finally spray-dried into a fine white powder that dissolves quickly in cosmetic bases.

You will most often see Sodium Hydrolyzed Casein in rinse-off and leave-in hair conditioners, reparative masks, hydrating facial moisturizers, anti-aging serums, after-sun lotions and hand creams where a softening touch is desired.

Sodium Hydrolyzed Casein’s Cosmetic Benefits/Uses

This milk-based peptide brings two main benefits to beauty formulas

  • Hair conditioning: The small peptides coat strands, filling in rough spots and helping hair feel smoother softer and easier to detangle. They can also boost shine by laying the cuticle flat.
  • Skin conditioning: On skin the peptides form a light moisture-binding film that leaves the surface feeling silky. This can improve overall hydration, reduce dry patches and give a supple look without heaviness or grease.

Who Can Use Sodium Hydrolyzed Casein

Sodium Hydrolyzed Casein is generally well tolerated by most skin and hair types. Dry, rough or chemically treated hair and dehydrated or mature skin often benefit the most from its smoothing moisture-binding effect, while normal and combination types also tend to enjoy a softer feel without greasiness. Oily or very acne-prone skin can still use it because the peptides are lightweight and water soluble, though those users may prefer formulas where this ingredient is paired with oil-control agents.

Because it is sourced from cow’s milk it is unsuitable for vegans and for strict vegetarians who avoid dairy-derived ingredients. People with a diagnosed milk protein allergy should avoid it altogether, even topically, as trace allergens could trigger a reaction.

Topical use during pregnancy or while breastfeeding is not known to pose a risk since the peptides remain on the skin surface and are not significantly absorbed. Still, this is not medical advice, and anyone who is pregnant or nursing should check with a healthcare professional before adding new personal care products.

Sodium Hydrolyzed Casein does not cause photosensitivity so there is no special sun-related caution needed beyond standard daily sunscreen use.

Potential Side Effects/Adverse Reactions

Reactions to Sodium Hydrolyzed Casein can differ from one person to another. The points below outline potential issues only and most users will not experience them when the ingredient is properly formulated in a product.

  • Allergic contact dermatitis in individuals sensitive to milk proteins
  • Redness, itching or mild stinging on highly reactive or compromised skin
  • Eye irritation if the product accidentally gets into the eyes
  • Product build-up on very fine hair leading to a weighed-down feel

If any irritation or other unwanted effect occurs stop using the product and consult a qualified healthcare provider or dermatologist.

Comedogenic Rating

Rating: 1/5

Sodium Hydrolyzed Casein is made of small, water-soluble peptides that rinse clean without leaving a heavy residue on skin. Because it lacks oily or waxy components that typically clog pores, the chance of it causing comedones is very low. A rating of 1 reflects this minimal risk while acknowledging that any film-forming ingredient might, in rare cases, contribute to congestion if layered with multiple rich products.

Suitable for acne-prone and breakout-prone users, especially when used in lightweight or rinse-off formulas.

As with all ingredients, the finished product’s full recipe, texture and the user’s own skin chemistry ultimately determine whether pores stay clear.

Summary

Sodium Hydrolyzed Casein works as both a hair and skin conditioner. The hydrolyzed milk peptides form a thin, moisture-grabbing film that smooths rough cuticles, boosts shine and leaves skin feeling soft and hydrated without greasiness. Its popularity sits in the mid-range: well known among formulators for its silky after-feel yet not as widely advertised as buzzier botanical proteins.

The ingredient is considered safe for topical use with a very low irritation and comedogenic profile, the main caveat being dairy allergies or strict vegan preferences. As with any new cosmetic active it is smart to do a small patch test before full use to ensure personal compatibility.

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