Sodium Octoxynol-2 Sulfate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Octoxynol-2 Sulfate?

Sodium Octoxynol-2 Sulfate is a synthetic surfactant made by linking ethylene oxide units to a branched octylphenol, then adding a sulfate group and neutralizing it with sodium. The result is a water-soluble powder or liquid that lowers surface tension, helping water mix evenly with oils and dirt. The ingredient first appeared in household cleaners in the mid-1900s when chemists looked for safer, milder alternatives to soap. Its mildness and strong cleaning power soon caught the attention of cosmetic formulators who needed reliable yet gentle surfactants for personal care products.

Production starts with octylphenol, which reacts with ethylene oxide to build a short polyethylene glycol chain of two units. This intermediate is then treated with sulfur trioxide to add the sulfate group, followed by neutralization with sodium hydroxide. Strict purification removes unreacted materials so the final ingredient meets cosmetic grade standards.

Today you will find Sodium Octoxynol-2 Sulfate in face cleansers, body washes, bubble baths, exfoliating masks, scalp scrubs, micellar waters, makeup removers, shaving foams, baby shampoos and even some lightweight moisturizers where a small amount of foam helps spread the formula evenly.

Sodium Octoxynol-2 Sulfate’s Cosmetic Benefits/Uses

Formulators choose this ingredient for two main jobs that improve how a product feels and performs on the skin or hair.

  • Cleansing: Its surfactant nature breaks down oils, sweat and everyday grime so they rinse away easily. This gives face and body cleansers a satisfying, thorough clean without leaving a tight sensation
  • Foaming: It creates a rich, stable lather that makes washing feel luxurious and helps users see where they have applied the product. A good foam also suspends dirt, allowing it to rinse off instead of redepositing on the skin

Who Can Use Sodium Octoxynol-2 Sulfate

This surfactant is generally suitable for normal, oily and combination skin because it removes excess oil without leaving heavy residue. Dry or very sensitive skin might find it a little too cleansing if used in high amounts or paired with other strong surfactants so those users should look for formulas that balance it with soothing agents.

Sodium Octoxynol-2 Sulfate is made entirely from laboratory sourced materials and contains no animal by-products which makes it acceptable for vegans and vegetarians.

No research shows a direct risk for pregnant or breastfeeding women when this ingredient is used in rinse-off or leave-on products at typical cosmetic levels. This is not medical advice and anyone who is pregnant or nursing should show the product to a healthcare professional before adding it to a routine.

The ingredient does not increase photosensitivity so it will not make skin more prone to sunburn. It is also odorless and non-volatile so it will not aggravate the airways during normal use.

Potential Side Effects/Adverse Reactions

Reactions to topical Sodium Octoxynol-2 Sulfate vary from person to person. The following is a list of potential side effects but most users will not notice any problems when the ingredient is used at the levels allowed in cosmetics.

  • Skin dryness prolonged or repeated exposure can strip natural oils especially on already dry skin
  • Mild irritation stinging or redness may occur on very sensitive or broken skin
  • Eye discomfort if the product accidentally enters the eyes it can cause temporary burning or watering
  • Allergic contact dermatitis rare but possible in people with an existing allergy to phenolic surfactants

If irritation or any other negative effect appears stop using the product and seek medical advice if symptoms persist.

Comedogenic Rating

Rating: 1/5. Sodium Octoxynol-2 Sulfate is a small, water-soluble surfactant that rinses away completely and does not leave an occlusive film on the skin. Because it lifts oil rather than adding any, the likelihood of it clogging pores is very low which is why it sits near the bottom of the comedogenic scale. People who are prone to acne or breakouts can usually use products containing this ingredient without extra concern, especially in rinse-off cleansers. One point is deducted from a perfect zero because prolonged contact in a leave-on formula could, in theory, disturb the skin barrier and trigger overproduction of sebum in extremely reactive skin.

Summary

Sodium Octoxynol-2 Sulfate works primarily as a cleanser and foaming agent. Its sulfate group and short polyethylene glycol chain allow it to latch onto both water and oil so grime lifts away easily while a stable lather forms for an enjoyable wash. Although it once appeared in many mainstream cleansers its use has tapered as brands explore sulfate-free marketing angles, yet it still shows up in niche face washes, scalp scrubs and baby bath products where gentle but effective foam is needed.

Current data show it to be safe at typical cosmetic concentrations with irritation risks limited to very sensitive skin or overuse. As with any new skincare ingredient it is wise to test a small patch first and monitor for redness, dryness or itching before applying it more broadly.

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