Sodium P-Chloro-M-Cresol: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium P-Chloro-M-Cresol?

Sodium P-Chloro-M-Cresol is the sodium salt form of 3-methyl-4-chlorophenol, a synthetic compound belonging to the chlorophenol family. It does not occur naturally; instead it is produced in the lab by chlorinating m-cresol, then neutralizing the resulting chlorophenol with sodium hydroxide to create a water-soluble powder. The ingredient emerged in the mid-1900s when chemists searched for reliable preservatives that could keep skin care and toiletry products free of harmful microbes. Because it showed strong activity against bacteria, yeast and mold, formulators quickly adopted it as a go-to preservative for creams, lotions, cleansing wipes, makeup removers, liquid soaps, deodorants, masks and other rinse-off or leave-on products. Its stability across a broad pH range and compatibility with many raw materials have helped cement its place in modern cosmetic manufacturing.

Sodium P-Chloro-M-Cresol’s Cosmetic Benefits/Uses

In topical beauty products Sodium P-Chloro-M-Cresol is valued for one key function that supports both product quality and user safety.

As an antimicrobial it acts as a preservative, suppressing the growth of bacteria, yeast and mold that could otherwise spoil a formula or cause skin irritation. By keeping the product microbially stable it extends shelf life, maintains texture and scent integrity and helps ensure that every application remains hygienic from the first use to the last.

Who Can Use Sodium P-Chloro-M-Cresol

This preservative is generally suitable for all skin types including oily, combination, normal and dry skin because it sits in the formula at very low levels and is rinsed or left on without changing the skin’s oil or water balance. Those with highly sensitive or compromised skin, such as people who have eczema or a damaged skin barrier, may prefer milder preservative systems because even small amounts of chlorophenols can occasionally trigger irritation.

Sodium P-Chloro-M-Cresol is a fully synthetic substance created from basic petrochemical feedstocks, so no animal-derived inputs are used during production. That makes it acceptable for both vegans and vegetarians.

Current cosmetic safety assessments have not flagged specific risks for pregnant or breastfeeding women when the ingredient is used within the low concentrations allowed by regulators. Still, this is not medical advice and anyone who is pregnant or nursing should clear any new skincare product with a doctor to be on the safe side.

The ingredient does not increase photosensitivity, so it will not make skin more prone to sunburn. It is also fragrance-free and non-volatile, meaning it will not contribute to scent issues or evaporate off the skin after application.

Potential Side Effects/Adverse Reactions

Reactions to topical Sodium P-Chloro-M-Cresol vary from person to person. The following list covers potential side effects yet most users will not experience them when the ingredient is used at the low percentages set by cosmetic regulations.

  • Skin irritation – mild redness, stinging or itching at the application site
  • Contact dermatitis – a more pronounced rash or inflammation in users who develop an allergy to chlorophenols
  • Eye irritation – possible if the product accidentally gets into the eyes during use
  • Rare systemic allergy – exceptionally uncommon but may occur in individuals with a known sensitivity to phenolic preservatives

If any discomfort, rash or other unexpected reaction appears, discontinue use and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5

Sodium P-Chloro-M-Cresol is water soluble and used in extremely small percentages, so it does not leave oily residues that could clog pores. It has no occlusive or fatty components and therefore earns a non-comedogenic score of 0. This makes it suitable for people who are prone to acne or breakouts. Because it targets microbes rather than influencing sebum or dead skin buildup, there is no evidence that it contributes to blackheads or pimples.

Summary

Sodium P-Chloro-M-Cresol serves mainly as a broad-spectrum antimicrobial preservative. By disrupting the cell walls of bacteria, yeast and mold it keeps creams, cleansers and other formulas stable so they smell, feel and perform the same from the first use to the last. While it enjoyed considerable popularity in the mid to late 20th century, many brands now opt for newer preservative blends so you may see it less often on ingredient lists. Regulatory reviews find it safe at the low limits set for cosmetics, with irritation or allergy remaining uncommon. As with any new product though, do a quick patch test to confirm personal tolerance before applying it widely.

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