Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer?

Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer is a water-soluble salt derived from a multibranched molecule called a dendrimer. The dendrimer’s core is pentaerythritol, a sugar alcohol obtained from petrochemical or plant sources, that is reacted step by step with hydroxypropyl iminodiacetic acid. Each reaction layer adds tiny arms to the core, creating a tree-like structure that ends with multiple sodium carboxylate groups. This architecture gives the ingredient a high surface area and many binding sites, which is why formulators prize it for its ability to grab on to metal ions and impurities.

Dendrimers first caught the attention of the cosmetic world in the late 1990s when researchers were looking for efficient, biodegradable alternatives to traditional chelating agents like EDTA. Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer gained traction because it pairs strong metal-binding power with a gentler environmental profile. Today it is produced in controlled reactors where temperature, pH and timing ensure each branching step is complete before the next begins. The final product is purified, spray-dried into a free-flowing powder or concentrated into an aqueous solution, then shipped to cosmetic labs worldwide.

You will most often spot this dendrimer in rinse-off cleansers, micellar waters, masks, facial washes, color cosmetics, anti-pollution serums, hair shampoos and conditioners. It can also appear in leave-on skincare such as lightweight moisturizers where it keeps formulas stable and boosts overall cleansing performance when the product is rinsed away at the end of the day.

Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer’s Cosmetic Benefits/Uses

This multitasking dendrimer improves both the performance and stability of many personal care formulas.

  • Chelating: Binds to metal ions like calcium, magnesium and iron that are naturally present in tap water or raw ingredients. By sequestering these metals it helps prevent discoloration, rancidity and texture changes, extending the shelf life of the product and keeping active ingredients effective.
  • Cleansing: Its branched structure traps and lifts away dirt, excess oils and pollutant particles from skin and hair. When used in facial cleansers or shampoos it boosts foam quality and rinses cleanly, leaving a fresh feel without residue.

Who Can Use Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer

This ingredient is water soluble, noncomedogenic and generally gentle, so it is considered suitable for all skin types including oily, dry, combination and sensitive skin. Because it does not leave a heavy film it works well for acne-prone complexions too. People with severely compromised or broken skin should still approach new products with caution since any additive can sting on open areas.

Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer is manufactured from petrochemical or plant-derived raw materials and involves no animal derivatives or by-products, making it acceptable for vegans and vegetarians.

The ingredient has no known hormonal activity and its large molecular size limits skin penetration, so it is not expected to pose a risk during pregnancy or breastfeeding. That said this is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product to a healthcare professional before use.

It does not increase photosensitivity, so daytime application does not require extra sun precautions beyond your normal sunscreen routine.

Potential Side Effects/Adverse Reactions

Responses to topical Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer differ from person to person. The effects below are possible yet uncommon when the ingredient is used at the low levels typical of cosmetics manufactured to industry standards.

  • Mild skin irritation such as transient redness or tingling
  • Dryness if used in very high concentrations or in formulas with strong surfactants
  • Allergic contact dermatitis in individuals sensitized to similar chelating agents
  • Eye irritation if a cleanser containing the ingredient is allowed to pool in the eyes

If any discomfort or persistent reaction occurs stop using the product and seek advice from a qualified health professional.

Comedogenic Rating

Rating: 0 out of 5. Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer is highly water soluble and has a bulky, branched structure that sits on the surface then rinses away without slipping into pores. It contains no oils, waxes or fatty acids that could encourage blockages, so it earns the lowest possible score.

This makes it a safe choice for people who are prone to acne or breakouts.

Because the molecule is designed to bind metals and dirt rather than skin lipids, it is unlikely to build up with repeated use which further supports its non-comedogenic profile.

Summary

Sodium Pentaerythrityl Hydroxypropyl Iminodiacetate Dendrimer is mainly a chelating and cleansing agent. Its tree-like branches provide dozens of sodium carboxylate end groups that magnetically grab onto metal ions, keeping formulas stable and colors true. The same structure traps grime and pollution so cleansers rinse skin and hair more thoroughly.

It is still a niche ingredient compared with household names like EDTA, yet its eco-friendlier profile and solid performance are helping it pop up in more modern cleansers, micellar waters and haircare products.

Current safety data show low irritation potential and virtually no risk of pore clogging, making it suitable for most users. As with any new cosmetic though it is wise to patch test a product first to rule out personal sensitivities.

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