Sodium Trichloroacetate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Trichloroacetate?

Sodium trichloroacetate is the sodium salt of trichloroacetic acid, a compound that looks like ordinary vinegar acid but with three chlorine atoms attached. Those chlorine atoms change its behavior, giving the ingredient strong cleaning and germ fighting traits. It is produced by reacting trichloroacetic acid with a neutralizing agent such as sodium hydroxide, creating a stable crystalline powder that dissolves easily in water-based formulas.

The parent acid was first studied in the late 19th century for laboratory use. As cosmetic science advanced in the mid-20th century, chemists noticed that the sodium salt’s ability to curb microbe growth could help keep products fresh without harsh preservatives. Over time formulators adopted it in small amounts to support product safety.

Today you might spot sodium trichloroacetate in rinse-off masks, exfoliating peels, spot treatment gels, clay cleansers and some specialty serums designed to maintain clarity. It is rarely the star ingredient but works quietly in the background to support formula stability.

Sodium Trichloroacetate’s Cosmetic Benefits/Uses

Sodium trichloroacetate serves one main purpose in cosmetics.

As an antimicrobial agent it helps limit the growth of bacteria, yeast and mold inside the bottle, extending shelf life and protecting the user from contamination. By controlling unwanted microbes it allows formulators to use lighter preservative systems, helping products stay gentle on skin while remaining safe to use over time.

Who Can Use Sodium Trichloroacetate

Sodium trichloroacetate is generally considered suitable for normal, oily and combination skin because it stays mostly in the background as a preservative helper rather than acting directly on living skin. Dry or very sensitive skin may prefer to avoid high-strength peels or masks that combine this ingredient with other acids, since the formula could feel more stripping or sting on compromised barriers.

The compound is fully synthetic and contains no animal derivatives, making it appropriate for both vegetarians and vegans.

Current data do not flag sodium trichloroacetate as a reproductive toxin. Still, out of an abundance of caution, women who are pregnant or nursing should ask their physician before using any product that lists it, especially leave-on treatments. This is not medical advice, simply a safety reminder.

The ingredient itself is not known to cause photosensitivity, and it does not make the skin more prone to sunburn once rinsed off. Daily sunscreen is still a good habit for everyone.

Potential Side Effects/Adverse Reactions

Reactions to topical sodium trichloroacetate differ from one person to the next. The effects below are possible but unlikely for most users when the ingredient is correctly dosed in a well-formulated product.

  • Transient tingling or stinging especially on freshly exfoliated, broken or highly sensitive skin
  • Dryness or mild peeling if the product is very acidic or used too often
  • Redness or irritation when combined with other strong actives like retinoids or alpha hydroxy acids
  • Contact dermatitis in the rare event of an individual allergy to chlorinated acetates
  • Eye irritation if the formula accidentally runs into the eyes during application or rinse-off

Stop using the product and consult a healthcare professional if any persistent burning, swelling or rash develops.

Comedogenic Rating

Rating: 0/5

Sodium trichloroacetate is a small water-soluble salt that does not leave an oily film or linger inside pores so it does not encourage blackheads or breakouts. Because it functions mainly as a preservative aid at very low levels it has virtually no chance of clogging follicles. For those prone to acne it is considered safe and unlikely to trigger new blemishes.

No notable interactions with sebum or skin lipids have been reported. Formulas that pair it with heavy emollients could still be comedogenic overall but that would be due to other ingredients not this one.

Summary

Sodium trichloroacetate acts primarily as an antimicrobial helper that keeps bacteria yeast and mold from multiplying in cosmetic products. By dissolving readily in water phases it spreads through the formula and disrupts microbial activity which supports a longer shelf life with fewer traditional preservatives.

The ingredient is relatively obscure compared with popular preservatives like phenoxyethanol so you will only find it in select masks peels and specialty treatments. Even so formulators value its ability to provide extra protection without adding heaviness or fragrance.

Current research shows it is low risk for most skin types when used at typical cosmetic concentrations. Still everyone’s skin is unique so doing a quick patch test with any new product containing sodium trichloroacetate is a smart move for peace of mind.

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