Solvent Red 49:1: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Solvent Red 49:1?

Solvent Red 49:1 is a synthetic dye created in laboratories rather than extracted from plants or minerals. Chemically it is known as N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium octadecanoate, a long name that reflects its complex organic structure. It belongs to the xanthene family of colorants, the same family that gives many bright pink and red shades their punch.

The first xanthene pigments appeared in the late 1800s when chemists were searching for stable hues for textiles. Over time formulators noticed these dyes stayed vibrant on skin and nails, which led to their gradual adoption in makeup during the mid-20th century. Today Solvent Red 49:1 is manufactured through a multi-step chemical reaction that joins a xanthene core with side chains that improve solubility in oils and waxes. After synthesis the dye is purified, dried then milled into a fine powder ready for blending into cosmetic bases.

Because it dissolves well in oils, butters and some alcohols, Solvent Red 49:1 is widely used in color-rich products such as lipsticks, tinted balms, liquid lip colors, nail enamels, blushes, eye shadows, hair coloring creams, bath bombs and some decorative soaps. Its bright red-pink tone offers formulators an easy way to create everything from soft coral to deep berry shades.

Solvent Red 49:1’s Cosmetic Benefits/Uses

In cosmetics Solvent Red 49:1 serves one clear purpose: it works as a colorant. By delivering a vivid red hue that disperses evenly in oily or waxy bases it lets brands craft attractive shades that catch the eye, help products stand out on shelves and give users the payoff they expect from makeup and personal care items.

Who Can Use Solvent Red 49:1

Because it is an inert colorant rather than an active treatment Solvent Red 49:1 is considered suitable for most skin types, including dry, normal, combination, oily and even sensitive complexions when used in well-formulated products. People with a history of dye allergies should be more cautious, as any synthetic pigment can occasionally provoke an adverse response.

The dye is synthesized from petrochemical feedstocks so it contains no animal-derived components, making it acceptable for vegans and vegetarians. As always the finished product must also be cruelty-free to meet personal ethics.

Current cosmetic safety assessments have not linked Solvent Red 49:1 to harm during pregnancy or breastfeeding when used topically in the small concentrations found in makeup. This is not medical advice and anyone who is pregnant or nursing should show their doctor all products they plan to use just to be safe.

The ingredient is not known to trigger photosensitivity, meaning it will not increase the skin’s tendency to sunburn. It also does not interfere with most common topical actives, so you can layer it alongside sunscreen, retinoids or acids without concern.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Solvent Red 49:1 vary from person to person. The points below list potential reactions only and most people will never experience them when the dye is included at approved levels in a properly made product.

  • Skin irritation such as redness burning or itching, most likely in those with pre-existing sensitivities to synthetic dyes
  • Allergic contact dermatitis marked by rash or swelling in rare cases
  • Temporary staining of skin nails fabric or bathroom surfaces if concentrated product is spilled or not fully removed
  • Eye irritation or watering if loose powder or product dust enters the eyes

If any of these issues occur stop using the item immediately and seek advice from a pharmacist or healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Solvent Red 49:1 is an inert pigment that sits on top of the skin and is used at very low concentrations, usually well under 1 percent of the total formula. It is not an oil or fatty acid, it does not clog pores on its own and it does not encourage the growth of acne-causing bacteria. For these reasons formulators consider it non-comedogenic.

Suitable for acne-prone and breakout-prone skin types.

The only time pore issues might arise is if the pigment is blended into a base that itself is heavy or occlusive. In that case the carrier ingredients, not the dye, would be the culprits.

Summary

Solvent Red 49:1 is a synthetic colorant valued for its ability to deliver vivid red and pink shades that disperse smoothly in oily or waxy cosmetic bases. It does not treat skin concerns or change texture, it simply provides reliable color payoff that stays bright over time.

The dye enjoys steady popularity in lip products, nail lacquers, blushes and eye shadows, though it is just one of many red pigments on the market so it is not a headline ingredient that drives marketing claims.

Current safety reviews show it is non-comedogenic, generally non-irritating and considered safe at the low levels permitted in cosmetics. Still, as with any new makeup or skin care item, perform a quick patch test to make sure your skin agrees with the full formula before regular use.

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