Sorbitan Sesquiisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sorbitan Sesquiisostearate?

Sorbitan Sesquiisostearate is a non ionic surfactant made by combining sorbitol, a sugar alcohol usually sourced from corn syrup, with isostearic acid, a fatty acid commonly obtained from vegetable oils such as soybean or rapeseed. Through a controlled heating process called esterification, the two ingredients bond to form a waxy, oil-soluble material with the official chemical description “sorbitan, isooctadecanoate (2:3).” First introduced to personal care labs in the mid-20th century, it quickly became valued for its reliable ability to keep oil and water phases mixed in creams and lotions. Today it appears in many cosmetic products including facial moisturizers, sunscreens, makeup removers, cleansing oils, foundations, masks, leave-on conditioners and anti aging treatments.

Sorbitan Sesquiisostearate’s Cosmetic Benefits/Uses

Its main job in a formula is emulsifying. By sitting at the boundary between oil and water droplets it helps them stay blended, which prevents separation in the jar and creates a smooth, uniform texture on the skin. This stable emulsion spreads evenly, feels pleasant, boosts the delivery of other ingredients and extends the shelf life of the product.

Who Can Use Sorbitan Sesquiisostearate

This emulsifier is generally considered suitable for all skin types. Dry and mature skin often benefits from the silky finish it gives creams, while normal and combination skin usually tolerates it just as well. People with very oily or congestion-prone skin can use it too because the ingredient itself is not known to clog pores, though extremely rich formulas that contain it might feel heavy on some complexions.

Sorbitan Sesquiisostearate is produced from plant-derived sorbitol and isostearic acid, so it is typically vegan and vegetarian friendly. Brands sometimes add animal-based co-ingredients to the same product, so label readers should still double-check if total animal-free status is important to them.

Current safety assessments show no special warnings for pregnant or breastfeeding women when this ingredient is used topically at the low levels found in cosmetics. That said this is not medical advice, and anyone who is expecting or nursing should run all skincare products past a doctor just to be safe.

The ingredient does not make skin more sensitive to sunlight, so routine daytime use poses no extra risk of sunburn. It also plays nicely with the vast majority of actives and preservatives, which is why formulators reach for it so often.

Potential Side Effects/Adverse Reactions

Side effects from topical Sorbitan Sesquiisostearate can vary from person to person. The points below describe potential reactions, but most users will not experience them when the ingredient is used correctly in a well-made product.

  • Mild skin irritation such as redness or itching, usually in people with very sensitive skin
  • Rare contact allergy that can lead to small bumps or a rash
  • Temporary eye discomfort if a product containing the ingredient accidentally gets into the eyes
  • Breakouts on skin that is extremely acne prone when used in a very heavy or occlusive formula

If any of these effects occur stop using the product and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1 out of 5. Sorbitan Sesquiisostearate is made from fatty acid esters yet its molecular structure is large and waxy so it tends to sit on the surface rather than seep into pores. It is also used in low concentrations, typically under 3 percent, further lowering the chance of clogging. Most acne prone users tolerate it well, though very rich creams that contain numerous heavy oils could still feel too occlusive for some skins. Overall it is considered suitable for those who are prone to breakouts.

Summary

Sorbitan Sesquiisostearate serves mainly as an emulsifier that keeps oil and water mixed which creates a smooth stable product that spreads easily and delivers actives evenly. It does this by positioning itself at the oil water interface, lowering surface tension and preventing separation during storage and use.

The ingredient is a quiet workhorse rather than a headline grabber yet its reliability, plant based origins and skin friendly profile keep it popular in moisturizers, sunscreens, makeup removers and hair conditioners across both drugstore and premium lines.

Current data shows it is low risk for irritation, non sensitizing and not likely to clog pores when used at normal cosmetic levels, but as with any new skincare ingredient it is wise to patch test a fresh product on a small area first to make sure your skin agrees with it.

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