Sr-Chloromonas Sp. Anf0048 Polypeptide-1: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sr-Chloromonas Sp. Anf0048 Polypeptide-1?

Sr-Chloromonas Sp. Anf0048 Polypeptide-1 is a peptide blend derived from Chloromonas sp. “King Sejong Station,” a strain of cold-adapted green microalgae first cataloged near South Korea’s Antarctic research base. Scientists noticed that this tiny plant survives extreme UV exposure and frigid winds by producing protective proteins. By cultivating the algae in controlled tanks, purifying the cell material and isolating its small protein fragments, manufacturers obtain a stable polypeptide that can be added to skincare formulas. The ingredient is water soluble, has a light molecular weight and mixes easily with creams, gels and serums. You will mainly see it in moisturizing lotions, recovery masks, soothing after-sun products, anti-aging ampoules and barrier-repair treatments where gentle yet noticeable skin comfort is the goal.

Sr-Chloromonas Sp. Anf0048 Polypeptide-1’s Cosmetic Benefits/Uses

In formulas this microalgae peptide delivers two key actions that work together for healthier looking skin:

  • Skin conditioning: Helps skin feel softer and smoother by supporting natural hydration and improving the look of surface texture. Users often report a quick boost in suppleness
  • Skin protecting: Forms a breathable shield that limits moisture loss and supports the skin’s own defense proteins, which can be weakened by sun, wind or indoor heating. This protective film can reduce visible redness and irritation, making the complexion appear calm and balanced

Who Can Use Sr-Chloromonas Sp. Anf0048 Polypeptide-1

This microalgae peptide is considered gentle enough for all skin types including dry, oily, combination and sensitive skin because it is water based and free of heavy occlusives or common irritants. Those with highly reactive skin generally tolerate it well since it helps reinforce the barrier instead of stripping it.

The ingredient is sourced from cultivated green microalgae so it is suitable for both vegans and vegetarians. No animal-derived materials are used during fermentation or purification.

Current data show no specific risks for pregnant or breastfeeding women when the peptide is used topically in standard cosmetic concentrations. Research is still limited though, and personal circumstances vary, so this information is not medical advice. Expectant or nursing mothers should review any new skincare product with their physician to be on the safe side.

Sr-Chloromonas Sp. Anf0048 Polypeptide-1 does not boost photosensitivity and can be worn morning or night, with or without sunscreen. It also layers well with acids, retinoids and niacinamide and has no known interactions with common actives.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Sr-Chloromonas Sp. Anf0048 Polypeptide-1 can vary from person to person. The points below cover potential issues only and are not expected to affect most users when the ingredient is properly formulated and used as directed.

  • Mild redness or flushing
  • Itching or tingling shortly after application
  • Allergic contact dermatitis in individuals sensitive to algae proteins
  • Temporary stinging if applied to freshly exfoliated or broken skin
  • Rare acne-like breakouts if combined with very occlusive bases on blemish-prone skin

If any adverse effect occurs discontinue use and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5. Sr-Chloromonas Sp. Anf0048 Polypeptide-1 is a small water-soluble peptide that does not leave an oily film or clog pores. It absorbs quickly and is usually delivered in lightweight serums or gels that rinse clean in normal cleansing routines. Because it contains no heavy oils, waxes or butters its chance of blocking follicles is virtually nil. For that reason it is generally considered safe for people who are prone to acne or breakouts. If used in a very rich formula the overall product, not the peptide itself, would determine the pore-clogging potential.

Summary

Sr-Chloromonas Sp. Anf0048 Polypeptide-1 is a microalgae-derived peptide that conditions skin and helps guard it against moisture loss. It softens surface texture by supporting the skin’s natural hydration network and forms a light protective veil that keeps external stressors at bay. Right now it is still a niche ingredient found mostly in K-beauty style recovery serums and after-sun masks, but interest is growing as brands look for gentle barrier boosters.

All current data point to a high level of safety for topical use with very low risk of irritation or clogged pores. As with any new skincare ingredient it is wise to patch test a fresh product first to make sure your skin agrees with it.

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