What Is Sr-Jellyfish Polypeptide-1 Sh-Oligopeptide-1?
Sr-Jellyfish Polypeptide-1 Sh-Oligopeptide-1 is a lab made fusion peptide inspired by proteins found in jellyfish and the well known skin rejuvenator sh-Oligopeptide-1, also called EGF. Scientists stitched together the genes that code for each peptide, then let friendly strains of E. coli read that genetic recipe and build the 291–amino acid chain during fermentation. After the bacteria finish their work the peptide is purified, filtered and dried into a stable powder ready for skincare labs.
Interest in marine peptides started in the 2000s when researchers noticed the resilience of jellyfish cells. At the same time EGF was gaining fame for its ability to signal skin renewal. Combining the two ideas led formulators to this hybrid ingredient that aims to borrow the best of both worlds.
Today Sr-Jellyfish Polypeptide-1 Sh-Oligopeptide-1 is mixed into lightweight serums, anti-aging creams, sheet masks, eye treatments and after-sun gels where brands want to showcase cutting edge peptide technology.
Sr-Jellyfish Polypeptide-1 Sh-Oligopeptide-1’s Cosmetic Benefits/Uses
This fusion peptide supports skin wellness in two main ways
- Antioxidant: Helps neutralize free radicals caused by UV rays and pollution which can lead to dullness and fine lines. By cutting down oxidative stress it supports a fresher more even-toned look.
- Skin protecting: Forms a light shield on the surface and encourages the skin’s natural repair signals. This can improve barrier strength so skin feels calmer softer and less prone to moisture loss.
Who Can Use Sr-Jellyfish Polypeptide-1 Sh-Oligopeptide-1
This peptide is lightweight and water based so it suits most skin types including dry, normal, combination and oily. Sensitive skin usually tolerates it well because it is free of fragrance and alcohol though anyone with a history of peptide allergies should proceed with extra care. Very reactive skin conditions such as active eczema or open wounds might find any new active uncomfortable until the barrier is calmer.
Because the ingredient is fermented in bacteria and contains no animal derived material it is considered suitable for both vegetarians and vegans.
No human data points to risks for women who are pregnant or breastfeeding. That said safety research on expectant or nursing mothers is limited so this information is not medical advice and anyone in these groups should show the full ingredient list of a product to their doctor before adding it to a routine.
The peptide itself does not increase photosensitivity and can be used morning or night. Regular sun protection is still recommended to guard against the free radicals the peptide is trying to neutralize.
Potential Side Effects/Adverse Reactions
Side effects from topical Sr-Jellyfish Polypeptide-1 Sh-Oligopeptide-1 differ from one person to the next. The following are potential reactions only and, when the ingredient is formulated correctly, most users will not notice any of them.
- Mild redness or warmth immediately after application
- Temporary itching or tingling in very sensitive skin
- Rare allergic response such as hives or swelling
- Breakout or congestion if the finished product uses heavy occlusive bases
- Contact irritation triggered by other ingredients in the same formula rather than the peptide itself
If any of these issues develop stop using the product and seek advice from a qualified healthcare provider or dermatologist.
Comedogenic Rating
Comedogenic rating: 0/5. Sr-Jellyfish Polypeptide-1 Sh-Oligopeptide-1 is a large water soluble peptide with no oily or waxy parts so it cannot lodge inside pores. Its molecules rinse away easily and do not form an occlusive layer that traps sebum.
Thanks to this pore friendly profile the ingredient is considered safe for people prone to acne or breakouts.
Keep in mind the rest of the formula counts too: if the product pairs the peptide with heavy butters or thick silicones overall clogging risk can rise even though the peptide itself remains non-comedogenic.
Summary
Sr-Jellyfish Polypeptide-1 Sh-Oligopeptide-1 is a bioengineered fusion peptide that delivers antioxidant defense and skin protecting support by neutralizing free radicals and nudging cells to reinforce the barrier so skin stays resilient hydrated and calm.
While not yet a household name the ingredient is slowly gaining traction in cutting edge serums masks and after sun gels as brands look for novel stories rooted in marine science and biotechnology.
Safety data so far show a low chance of irritation allergy or pore clogging but every skin behaves differently so patch testing a new product is still the smartest move.