Streptomyces Hygroscopicus/Glucose Ferment Filtrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Streptomyces Hygroscopicus/Glucose Ferment Filtrate?

Streptomyces Hygroscopicus/Glucose Ferment Filtrate is a skin care ingredient that starts with a natural soil bacterium called Streptomyces hygroscopicus. In the lab this microorganism feeds on glucose, creating a rich broth during fermentation. After fermentation the mixture is carefully filtered to remove the bacteria and leave behind the clear fluid we see on an ingredient list. This fluid contains a blend of small molecules like peptides, sugars and humectant compounds that come from the glucose as well as metabolites produced by the bacterium.

Scientists began studying Streptomyces ferment filtrates in the late 20th century when fermentation technology became more precise and affordable for cosmetic use. Brands were looking for gentle bio-derived ingredients that could lock in moisture without feeling heavy. The filtrate from S. hygroscopicus proved to be effective so formulators started adding it to moisturizers, hydrating serums, overnight masks and soothing after-sun treatments. Today you will most often find it in products that promise lasting hydration, extra skin comfort or a protective finish.

Streptomyces Hygroscopicus/Glucose Ferment Filtrate’s Cosmetic Benefits/Uses

This ferment filtrate brings one main benefit to skin care formulas.

As an occlusive ingredient it forms a light protective film on the skin surface. This film helps slow down water loss so skin stays hydrated for longer. Because the film is thin and breathable it does not leave a greasy feel, making the ferment a good choice for lotions, gels and even some lightweight serums aimed at all skin types. By reducing transepidermal water loss it helps the skin look smoother and feel softer throughout the day.

Who Can Use Streptomyces Hygroscopicus/Glucose Ferment Filtrate

This ferment filtrate is generally suitable for all skin types. Dry or mature skin benefits from the extra moisture retention while normal and combination skin appreciate its lightweight feel. Even oily and sensitive skin usually tolerate it well because the film it forms is thin and non-greasy, though people with extremely acne-prone skin who react to most occlusives may prefer to monitor how their skin responds.

The ingredient is produced from a microorganism and plant-derived glucose so it contains no animal-based substances, making it appropriate for both vegans and vegetarians.

No specific warnings exist for pregnant or breastfeeding women. The material is considered low risk when used topically in cosmetic concentrations, yet this is not medical advice and anyone who is pregnant or nursing should confirm suitability with their doctor.

Streptomyces Hygroscopicus/Glucose Ferment Filtrate does not increase photosensitivity, and it plays well alongside common actives such as niacinamide or hyaluronic acid without diminishing their effect.

Potential Side Effects/Adverse Reactions

Side effects from topical Streptomyces Hygroscopicus/Glucose Ferment Filtrate vary from person to person. The following is a list of potential reactions but most users will not experience any of them when the ingredient is formulated and used correctly.

  • Irritation or redness – a rare response in very sensitive or compromised skin barriers
  • Allergic contact dermatitis – possible if someone is specifically allergic to fermentation by-products or the preservative system in the formula
  • Breakouts – a small number of individuals with highly acne-prone skin may notice clogged pores when using any occlusive film formers
  • Product separation or spoilage – if the formula’s preservative system is inadequate the ferment could promote microbial growth which in turn may irritate skin

Discontinue use and seek medical advice if any negative reaction develops while using this ingredient or products containing it.

Comedogenic Rating

Rating: 1/5. Streptomyces Hygroscopicus/Glucose Ferment Filtrate forms a very thin breathable film so it is far less likely to trap excess oil or dead skin compared with heavier occlusives like mineral oil or lanolin. Most users, including those with combination or oily skin, report no pore clogging at typical use levels of 1-3 percent in leave-on products.

Suitable for acne-prone skin in most cases although extremely reactive or congested skin types should monitor for any increase in breakouts.

The overall comedogenic impact also depends on the full formula; if the product contains other high-risk ingredients or a weak preservative system the chance of clogged pores can rise.

Summary

Streptomyces Hygroscopicus/Glucose Ferment Filtrate is mainly valued for its occlusive property: it lays down a micro-thin film that slows water escape from the skin surface which helps maintain softness and smoothness through the day. Because the film is lightweight and non-greasy formulators can add it to gels, lotions and masks without making them feel heavy.

While not as famous as hyaluronic acid or glycerin this ferment is gaining quiet popularity in K-beauty style hydrating serums and clean beauty moisturizers that market bio-fermented ingredients.

Current research and industry safety reviews rate it as low risk with only rare irritation or allergy reports. Still, skin can be unpredictable so patch testing any new product is a smart precaution before full-face use.

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