Sucrose Octaacetate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sucrose Octaacetate?

Sucrose octaacetate is a modified form of regular table sugar that has been reacted with acetic acid to replace all eight of the sugar’s natural hydroxyl groups with acetate groups. This change turns the sweet sugar molecule into a bitter, oily liquid or solid that blends more easily with oils and alcohol-based solutions. The starting material is usually sucrose harvested from sugarcane or sugar beet. Chemists discovered the compound in the late 1800s while exploring ways to create new flavors and fragrances. By the mid-20th century its strong bitterness made it useful for discouraging accidental ingestion of household products, a trait that later carried over to cosmetics.

To make sucrose octaacetate, manufacturers purify food-grade sucrose, dissolve it in a solvent such as acetic anhydride, then add an acid catalyst. The mixture is warmed so the acetate groups attach to the sugar. Afterward the product is washed, filtered and dried before being milled into a fine powder or melted into a clear liquid.

In modern beauty formulas, sucrose octaacetate shows up in perfumes, body sprays, nail polish removers, facial toners, aftershaves, and even some lip or nail treatment products where its bitterness helps keep the user from licking or biting.

Sucrose Octaacetate’s Cosmetic Benefits/Uses

This ingredient serves two main roles in personal care products:

  • Denaturant: Added to alcohol-based items like fragrance mists and toners, sucrose octaacetate imparts an intense bitter taste. This makes the alcohol unpleasant to drink, helping brands meet legal rules that separate cosmetic alcohol from drinkable spirits.
  • Fragrance: Though bitter when tasted, it has a faint, pleasant odor that can round out scent blends. Perfumers and formulators use it in small amounts to add subtle depth or to mask unwanted chemical smells from other raw materials.

Who Can Use Sucrose Octaacetate

Sucrose octaacetate is considered non-comedogenic and generally friendly for all skin types, including oily, combination, normal and even sensitive complexions. That said its bitter taste usually appears in alcohol-based products, so very dry or easily irritated skin may feel a bit tight if the overall formula has a high alcohol content.

The ingredient is made from plant-derived sucrose and acetic acid, with no animal by-products or animal testing requirements, so it is suitable for vegans and vegetarians.

No specific warnings exist for pregnant or breastfeeding women when this ingredient is used in topical cosmetics. Systemic absorption is minimal, yet this is not medical advice and anyone who is expecting or nursing should run all personal care products past a qualified health professional to be safe.

Sucrose octaacetate is not known to increase sun sensitivity, does not interfere with common active ingredients and has no documented age-related restrictions.

Potential Side Effects/Adverse Reactions

Reactions to topical use of sucrose octaacetate vary from person to person. The points below list potential side effects, but most people will not experience them when using a well-formulated product.

  • Mild skin irritation or redness, especially on broken or freshly shaved skin
  • Dryness or stinging linked to the high alcohol content of some products that carry it
  • Contact dermatitis in individuals with a specific sensitivity to acetates
  • Eye irritation if the product accidentally splashes into the eyes
  • Unpleasant bitter taste if lip products are overapplied or accidentally ingested

If you experience any of these effects stop using the product and consult a healthcare professional or dermatologist for guidance

Comedogenic Rating

Rating: 0 (non-comedogenic)

Sucrose octaacetate is a large, highly branched molecule that does not penetrate deeply into pores and is used at very low concentrations, usually below 0.1 percent. It sits on the surface, delivers bitterness or a light scent, then evaporates or is washed away without leaving an oily film. Because it is structurally different from fatty oils and waxes that can block follicles, it earns the lowest possible score on the comedogenic scale.

That makes the ingredient perfectly fine for people prone to acne or breakouts.

The only caveat is that it often appears in formulas rich in drying alcohol, so those with inflamed acne should watch for overall formula balance.

Summary

Sucrose octaacetate works mainly as a denaturant and a subtle fragrance helper. Its intense bitterness makes cosmetic alcohol undrinkable which keeps products compliant with regulations, while its faint odor smooths out harsh chemical notes in perfumes, body sprays and other alcohol-based items.

It is a niche ingredient rather than a household name, popping up most often in professional fragrance bases, nail care and a handful of lip products where its taste deters biting. You will not see it topping trend charts but formulators appreciate its efficiency and plant-derived origin.

Safety data mark it as low risk with minimal skin irritation potential, no pore-clogging issues and virtually zero systemic absorption. Still, skin is personal so patch testing any new product that contains sucrose octaacetate is a smart precaution.

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