T-Butylphenyl Ethyl Glyceryl Diether: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is T-Butylphenyl Ethyl Glyceryl Diether?

T-Butylphenyl Ethyl Glyceryl Diether, sometimes listed on labels as t-Butylphenoxy Ethoxy Isopropanol, is a lab-made molecule created by linking a butylphenyl group to a small chain of ethyl and glycerol units. Chemists designed it to be both water friendly and oil friendly, allowing it to sit comfortably in a wide range of skincare bases. The ingredient first started appearing in cosmetic research in the early 2000s when formulators were looking for lightweight antioxidants that would stay stable in modern water-rich creams. Production begins with phenol derived from petroleum or plant feedstocks. Through a series of controlled steps, technicians attach a tert-butyl group for extra stability, then add ethoxy and isopropanol sides to improve skin feel. The final material is purified, quality-checked and shipped as a clear fluid.

You will most often spot T-Butylphenyl Ethyl Glyceryl Diether in daily moisturizers, anti-aging serums, sheet masks, lightweight lotions and after-sun treatments. Its pleasant, non-greasy touch makes it easy to incorporate without changing the texture consumers expect.

T-Butylphenyl Ethyl Glyceryl Diether’s Cosmetic Benefits/Uses

This ingredient pulls double duty in formulations, helping products last longer while giving skin an added boost.

  • Antioxidant: It scavenges free radicals created by UV light and pollution, helping to protect both the product and the skin from oxidative stress. This can keep the formula fresh for longer and support a brighter, more even-toned complexion.
  • Humectant: It attracts and binds moisture from the air, adding lightweight hydration to the upper layers of skin. This helps maintain a smooth, plump look without a heavy or greasy feel.

Who Can Use T-Butylphenyl Ethyl Glyceryl Diether

T-Butylphenyl Ethyl Glyceryl Diether is considered skin friendly for most skin types including normal, dry, combination and oily skin thanks to its lightweight, non-greasy texture. Sensitive skin generally tolerates it as well because it is fragrance free and has a low irritation profile. There are no known issues for darker or lighter skin tones.

The ingredient is made entirely from synthetic sources and contains no animal by-products, so it is suitable for vegans and vegetarians.

No data suggest that it poses a special risk during pregnancy or while breastfeeding when used topically in cosmetic amounts. This is not medical advice and anyone who is pregnant or nursing should consult a healthcare professional before adding new skincare products, just to be safe.

T-Butylphenyl Ethyl Glyceryl Diether does not make skin more sensitive to the sun and can be used both day and night without raising the risk of sunburn. Normal sun protection practices should still be followed.

It layers well with most common actives such as vitamin C, niacinamide and retinol and does not interfere with mineral or chemical sunscreens.

Potential Side Effects/Adverse Reactions

Reactions to topical T-Butylphenyl Ethyl Glyceryl Diether vary from person to person. The issues listed below are possible but uncommon when the ingredient is used at standard cosmetic levels.

  • Mild skin irritation temporary redness or stinging in very sensitive users
  • Contact allergy rare cases of itching or rash in individuals with a specific sensitivity to phenolic compounds
  • Acne flare isolated reports of clogged pores when used in very heavy cream bases on acne-prone skin
  • Eye discomfort slight watering or burning if the product accidentally enters the eyes

If any unexpected irritation or discomfort occurs discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 1 / 5

T-Butylphenyl Ethyl Glyceryl Diether is a small, lightweight molecule that sits mostly on the surface and draws in water rather than oil, so it has little tendency to clog pores. It lacks fatty acids or heavy waxes that usually bump up comedogenic scores. In very rich creams the overall formula, not this ingredient alone, could still trap oil in acne-prone skin but the diether itself is considered low risk.

Suitable for most people who deal with blackheads or breakouts, though ultra sensitive, congestion-prone users should still watch how their skin reacts when the ingredient is part of a thick, occlusive base.

Summary

T-Butylphenyl Ethyl Glyceryl Diether acts as both an antioxidant and a humectant. The tert-butylphenyl part donates electrons to neutralize free radicals from sun and pollution, helping keep skin tone even and the product stable. The ethyl glyceryl side attracts water and holds it at the skin surface for a soft, hydrated feel without greasiness.

Right now the ingredient shows up mainly in newer Asian and indie formulas rather than in big legacy brands, so you may not spot it on every shelf. Formulators like it because it gives a clean texture and extends shelf life without needing a high dose.

Overall safety data look good: low irritation risk, minimal pore-clogging potential and no known long-term concerns at cosmetic levels. As with any new product though it is smart to perform a small patch test first to be sure your skin agrees with the full formula.

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