Tetrasodium Dicarboxymethyl Aspartate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Tetrasodium Dicarboxymethyl Aspartate?

Tetrasodium Dicarboxymethyl Aspartate is a synthetic salt derived from the naturally occurring amino acid L-aspartic acid. Chemically it belongs to a group of molecules known as chelating agents that can bind to metal ions. The compound was first explored in the 1990s as an environmentally friendlier alternative to older chelators like EDTA which can persist in waterways. Production starts with fermenting plant-based sugars to obtain L-aspartic acid, which is then reacted with formaldehyde and sodium salts under controlled pH to attach two carboxymethyl groups, yielding a water-soluble powder. Because it is readily biodegradable and effective at low concentrations it found its way into cosmetics as brands looked for greener ingredient options. Today it is commonly blended into facial cleansers, moisturizers, shampoos, conditioners, anti-aging serums and sheet masks where product stability and texture are important.

Tetrasodium Dicarboxymethyl Aspartate’s Cosmetic Benefits/Uses

This ingredient serves one key purpose in personal care formulas: it acts as a chelating agent. By binding to trace metals that may be present in water or raw materials it prevents those metals from reacting with other ingredients. This helps stop discoloration, rancidity and texture changes, keeping colors true and fragrances fresh while extending shelf life. It also improves the performance of surfactants so cleansers foam more evenly and conditioners rinse out smoothly.

Who Can Use Tetrasodium Dicarboxymethyl Aspartate

This chelating salt is considered gentle enough for all skin types including oily, dry, combination and sensitive skin because it does not interact directly with the skin’s own lipids or proteins and is used at very low levels. It is water soluble and rinses away cleanly so it rarely leaves residue that might upset reactive complexions.

The molecule is produced from fermented plant sugars and synthesized without any animal-derived substances which makes it suitable for both vegans and vegetarians. Most suppliers also certify it as cruelty free.

Current safety data show no reproductive or developmental concerns at the tiny amounts applied in cosmetics so pregnant and breastfeeding women can generally use products containing it. This is not medical advice so anyone who is expecting or nursing should still double-check any skincare routine with a healthcare professional just to be safe.

Tetrasodium Dicarboxymethyl Aspartate does not make skin more sensitive to sunlight so it does not raise the risk of sunburn. It is also odorless and non-volatile which means it will not aggravate fragrance sensitivities or trigger migraines in scent-reactive users.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Tetrasodium Dicarboxymethyl Aspartate can vary from person to person. The points below outline potential reactions that could occur even though they are uncommon and most users will not notice any issues when the ingredient is formulated correctly.

  • Mild skin irritation in the form of transient itching or tingling, usually when used in very high concentration
  • Redness or slight warmth on extremely sensitive or compromised skin barriers
  • Allergic contact dermatitis for individuals already sensitized to similar chelating agents
  • Eye stinging or watering if a product containing the ingredient accidentally gets into the eyes

If any of these reactions develop stop using the product and consult a qualified healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 0/5. Tetrasodium Dicarboxymethyl Aspartate is a small water-soluble salt that rinses away fully and does not form a film on skin or mix with skin oils, so it cannot block pores. Because it works in the water phase and is used at very low levels it has virtually no chance of contributing to blackheads or breakouts.

Suitable for acne-prone skin.

Some formulators like this chelator because it even helps prevent soap scum from sticking to skin, which can further cut down on pore congestion.

Summary

Tetrasodium Dicarboxymethyl Aspartate is mainly a chelating agent that grabs stray metal ions so colors stay bright, fragrances stay fresh and formulas keep their texture. By doing this it also lets cleansers foam better and conditioners feel silkier.

While not as famous as big-name actives it is gaining ground as a greener swap for EDTA, especially in clean beauty lines that want biodegradable ingredients.

Safety data show it is low risk for almost everyone when used in typical cosmetic amounts, but as with any new product it is smart to do a quick patch test first to be sure your skin agrees with the full formula.

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