Thiram: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Thiram?

Thiram is a synthetic compound belonging to the dithiocarbamate family, technically known as tetramethylthiuram disulfide. It is produced in an industrial setting by reacting dimethylamine with carbon disulfide, then gently oxidizing the resulting salt to form the final disulfide structure. The presence of sulfur atoms in its backbone gives the ingredient strong activity against a wide range of microbes.

First introduced in the 1940s as a rubber-processing aid and agricultural fungicide, chemists soon recognized that its ability to curb fungal and bacterial growth could be valuable in personal care. Over time small, carefully controlled amounts of thiram found their way into cosmetic formulations where maintaining product freshness is crucial.

Today thiram may appear in masks, rinse-off cleansers, foot creams, deodorants, sunscreens, lotions, gels and other products that benefit from extra protection against spoilage. Its inclusion helps manufacturers extend shelf life so consumers can enjoy safe, stable textures and scents.

Thiram’s Cosmetic Benefits/Uses

Thiram serves a single but important role in cosmetics.

As an antimicrobial, it suppresses the growth of bacteria, yeast and mold that could otherwise contaminate a product after it is opened. This keeps textures smooth, colors true and fragrances untainted while also protecting the user from potential skin infections linked to spoiled products.

Who Can Use Thiram

Because its purpose is to keep formulas free from microbes rather than to treat the skin itself, thiram can technically be used in products for most skin types. Oily and combination skin tend to tolerate it best since they are less prone to dryness or barrier fragility. Normal skin generally does well too. Those with sensitive, very dry or eczema-prone skin should approach with caution, as thiram may provoke irritation when the skin barrier is already compromised.

The ingredient is synthetically produced and contains no animal-derived matter, so it is considered suitable for vegans and vegetarians. As with any raw material individual brands may differ in animal-testing policies, so shoppers who prioritise cruelty-free status should verify a product’s overall certification.

Data on topical thiram during pregnancy or breastfeeding are limited. While the small amounts used in finished cosmetics are unlikely to pose risk, this is not medical advice and anyone who is pregnant or nursing should have their healthcare provider review any product containing thiram before use.

Thiram is not known to increase photosensitivity, so extra sun protection beyond the usual daily SPF is not required solely because a product contains it. Since it functions behind the scenes as a preservative there are no special application rules other than following the product’s instructions.

Potential Side Effects/Adverse Reactions

Side effects from topical thiram vary from person to person. The points below outline potential reactions but they are uncommon when the ingredient is used correctly in a well-formulated product.

  • Skin redness or stinging
  • Dry patches or mild peeling
  • Contact dermatitis presenting as itching or rash
  • Allergic sensitisation after repeated exposure
  • Eye irritation if the product is inadvertently rubbed into the eye area

If any of the above reactions occur discontinue use immediately and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5. Thiram is water-soluble and used at very low amounts, so it does not sit on skin or clog pores the way heavy oils or waxes can. That low residue profile keeps the risk of blocked follicles minimal. Because of this it is generally considered acceptable for people who are prone to acne or breakouts. The main concern with thiram is irritation rather than pore blockage, which is why its comedogenic rating stays near the bottom of the scale.

Summary

Thiram is included in cosmetics for one clear reason: its strong antimicrobial power keeps bacteria, yeast and mold from spoiling a formula. By killing or disabling unwanted microbes it helps products stay fresh, smell right and remain safe for use throughout their shelf life. It is not a trendy skin care hero and you will mostly spot it in niche or utilitarian items rather than in big marketing campaigns. Safety data show that the low levels used in cosmetics are broadly well tolerated, though sensitive skin may react. As with any new product it is smart to do a quick patch test before committing it to your routine.

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