Tri-C12-15 Alketh-6 Phosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Tri-C12-15 Alketh-6 Phosphate?

Tri-C12-15 Alketh-6 Phosphate is a lab-made ingredient created by reacting medium-chain synthetic alcohols (with 12 to 15 carbon atoms) with about six units of ethylene oxide, then linking three of those alcohol chains to phosphoric acid. The result is a mild, water-compatible molecule that behaves a bit like both oil and water, which is why it is so useful in personal care products.

Its roots trace back to the mid-late twentieth century when chemists were looking for gentler alternatives to traditional soaps. By tweaking the length of the alcohol chains and the amount of ethoxylation, formulators discovered they could fine-tune cleansing power and skin feel. As phosphate esters proved effective yet milder than sulfates, Tri-C12-15 Alketh-6 Phosphate found its way into shampoos during the 1970s and soon after into facial cleansers and lotions.

The ingredient is manufactured in a controlled, multi-step process that starts with petrochemical or plant-derived alcohols. After ethoxylation, the alcohol is reacted with phosphoric acid under carefully monitored temperatures and pH. The finished material is then neutralized and purified to meet cosmetic-grade standards.

Today you will spot Tri-C12-15 Alketh-6 Phosphate in foaming face washes, micellar waters, clarifying shampoos, cream cleansers, light moisturizers, makeup removers and even some wash-off masks where a gentle yet effective cleansing action is desired.

Tri-C12-15 Alketh-6 Phosphate’s Cosmetic Benefits/Uses

Formulators rely on this versatile ingredient for two main reasons:

  • Cleansing: Its amphiphilic structure lifts away dirt, oil and makeup while producing a soft, low-irritation foam that rinses clean without leaving a tight feeling on skin or hair
  • Emulsifying: It helps oil and water mix smoothly so creams, lotions and cleansing milks stay uniform, feel light and remain stable over time

Who Can Use Tri-C12-15 Alketh-6 Phosphate

This ingredient is generally well tolerated by most skin types including oily, combination, normal and even sensitive skin thanks to its mild cleansing profile. Extremely dry or eczema-prone skin might find it a bit too cleansing if used in high amounts but in well-balanced formulas it is usually gentle enough.

Tri-C12-15 Alketh-6 Phosphate is made from synthetic alcohols and phosphoric acid, so it contains no animal-derived material. That makes it suitable for vegans and vegetarians as long as the finished product is certified cruelty free.

Current safety reviews show no specific risks for women who are pregnant or breastfeeding when the ingredient is used in rinse-off or leave-on cosmetics at typical levels. This is not medical advice and anyone who is pregnant or nursing should check with a doctor before using new skincare products just to be safe.

The molecule does not make skin more sensitive to sunlight, so it is not considered photosensitizing. It is also fragrance-free and nonvolatile which lowers the chance of inhalation or photoreaction issues.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical use of Tri-C12-15 Alketh-6 Phosphate can vary from person to person. The points below list potential issues that could occur, though most users will not experience them when the ingredient is used correctly in a finished product.

  • Mild skin irritation such as temporary redness or stinging, usually if the formula is left on the skin for a long time or used too frequently
  • Dryness or tightness especially on already dehydrated or compromised skin when used in high-foaming cleansers
  • Allergic contact dermatitis in rare cases for individuals sensitive to phosphate esters or residual processing agents
  • Eye irritation if the product accidentally gets into the eyes, leading to watering or mild burning that should subside after rinsing

If any uncomfortable reaction occurs stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1/5

Tri-C12-15 Alketh-6 Phosphate is a water-compatible cleansing agent that rinses off easily and does not leave a greasy film that could block pores. Its molecular structure is more surfactant than oil so it has very little tendency to build up inside follicles, which is why its comedogenic potential is considered low.

Suitable for most acne-prone or breakout-prone skin types, although the overall formula it sits in can change how pore-friendly the final product is.

Because it is usually found in rinse-off cleansers any brief residue is minimal and unlikely to contribute to blackheads or whiteheads. In leave-on lotions it is still low risk but performance will depend on accompanying emollients.

Summary

Tri-C12-15 Alketh-6 Phosphate cleanses by surrounding dirt and oil so they can be rinsed away and it emulsifies by helping water mix smoothly with oils, which keeps creams and cleansing milks stable and lightweight. Thanks to this dual role it shows up in face washes, micellar waters, light lotions and haircare targeting a gentle feel.

It is not the biggest star in skincare but formulators value it as a quiet workhorse that delivers mild foam and stability without fuss. Safety reviews rate it as low risk at typical use levels and most people tolerate it well. Still, whenever you introduce a new product containing Tri-C12-15 Alketh-6 Phosphate it is smart to patch test first in case your skin happens to disagree.

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