Trifolium Pratense Leaf Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Trifolium Pratense Leaf Extract?

Trifolium Pratense Leaf Extract is a plant-based ingredient made from the leaves of red clover, a flowering legume long known in herbal traditions. The leaves hold naturally occurring compounds such as isoflavones, flavonoids and phenolic acids, all of which give the extract its antioxidant strength. Red clover teas and poultices were once common in folk beauty rituals, and as modern formulators looked for gentle botanical antioxidants this leaf extract moved from the herb garden into the laboratory.

To produce the extract, freshly harvested or carefully dried red clover leaves are cleaned, milled and steeped in a cosmetic-grade solvent like glycerin, water or a light alcohol. The liquid then passes through filters that remove plant solids, leaving a clear solution rich in active molecules. After standard safety tests and quality checks, the resulting fluid or powder becomes a stable raw material ready for creams, serums and other skin care products.

You will often see Trifolium Pratense Leaf Extract in antioxidant face serums, revitalizing masks, daily moisturizers, anti-aging lotions, after-sun soothers and scalp or hair treatments that aim to calm skin at the root.

Trifolium Pratense Leaf Extract’s Cosmetic Benefits/Uses

This extract brings two main qualities to a formula

  • Antioxidant: Helps neutralize free radicals created by UV light or pollution which can lead to dullness and early lines. By limiting oxidative stress it supports a fresher, more even look and helps protect other delicate ingredients in the product
  • Skin conditioning: Contributes to a soft, smooth feel on application. The plant’s natural sugars and flavonoids add light hydration and comfort, making the skin appear supple and well cared for

Who Can Use Trifolium Pratense Leaf Extract

Red clover leaf extract suits most skin types including normal, dry, combination and oily because it is lightweight and does not add heavy oils. Its gentle, soothing profile makes it a handy option for sensitive skin as well, although anyone with a known legume allergy should be cautious since red clover belongs to the pea family.

The extract is plant derived with no animal by-products, so it is appropriate for vegans and vegetarians. Manufacture typically involves water, glycerin or cosmetic alcohols rather than animal sourced solvents.

No data points to problems for pregnant or breastfeeding women when the extract is used on skin, yet hormonal links have been noted for concentrated oral supplements of red clover. Topical use is far less potent, but this is not medical advice and anyone who is pregnant or nursing should check with a doctor before adding new products.

The ingredient does not make skin more sensitive to sunlight, so it does not increase the risk of sunburn. Routine daytime sun protection is still encouraged for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to the topical use of Trifolium Pratense Leaf Extract differ from person to person. The points below list potential side effects that could occur though they are unlikely for most users when the extract is formulated and used correctly.

  • Localized redness or irritation
  • Mild itching or stinging on application
  • Contact dermatitis in individuals allergic to legumes
  • Very rare hormonal sensitivity such as breast tenderness in those who are highly sensitive to plant estrogens

If any unwanted reaction appears stop using the product and consult a healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 0–1 (very low)

Trifolium Pratense Leaf Extract is mostly water soluble and contains minimal oils or heavy waxes that could clog pores. Its main components are light antioxidants and sugars that sit on the surface and rinse away easily, so the risk of blocking follicles is tiny.

Because of this low score it is generally suitable for skin that is prone to acne or breakouts.

Formulas that combine the extract with richer butters or occlusive silicones could bump up the overall pore-clogging risk, so always look at the full ingredient list of the finished product.

Summary

Trifolium Pratense Leaf Extract offers antioxidant support that helps neutralize free radicals and mild skin conditioning that softens and comforts the surface. It delivers these perks through naturally occurring isoflavones, flavonoids and gentle plant sugars.

While not the most famous botanical on the shelf it appears more often in modern clean beauty lines that value plant based antioxidants. Its light texture and flexible use in serums, creams and scalp care make it an easy add-in for formulators.

Safety records show it is well tolerated for most skin types with only rare irritation or allergen concerns. As with any new skincare ingredient it is smart to patch test a small area first to be sure your skin agrees with it.

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