Trihydroxymethoxystearin: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Trihydroxymethoxystearin?

Trihydroxymethoxystearin is a plant-derived fatty acid ester made from stearic acid and glycerin that has been modified with extra hydroxyl and methoxy groups. On an ingredient list you might also see it described by its chemical name Octadecanoic acid, methoxyhydroxy-, propanetriyl ester. These tweaks to the familiar stearic acid backbone give the molecule a buttery texture and a strong ability to hold water.

The cosmetic world first explored this compound in the early 2000s while looking for richer yet non-greasy alternatives to mineral oils. Researchers found that adding the extra hydroxyl groups raised its melting point and stability, making it ideal for creams that need to stay smooth at room temperature. Today most commercial material is made by reacting purified stearic acid from vegetable oils with glycerol under controlled heat then introducing a mild methoxylation step. The finished wax-like solid is filtered, cooled and milled into a fine powder for easy blending.

You will most often spot Trihydroxymethoxystearin in thick moisturizers, night creams, lip balms, solid cleansing bars, masks and high-coverage foundations where a creamy skin feel is prized. It also shows up in anti-aging formulas that aim to leave a protective veil on the skin surface.

Trihydroxymethoxystearin’s Cosmetic Benefits/Uses

This ingredient pulls double duty in many formulas

  • Skin conditioning – It forms a soft film that smooths rough patches and locks in hydration so skin feels supple and comfortable after application
  • Emollient – The waxy texture fills tiny gaps between skin cells which helps products glide on easily and leaves a silky, non-tacky finish

Who Can Use Trihydroxymethoxystearin

Thanks to its buttery yet non greasy feel, Trihydroxymethoxystearin works well for normal, dry and combination skin that needs extra softness and moisture. Sensitive skin usually tolerates it because it has no fragrance or known irritants. Very oily or acne prone skin may find it a little rich if used in high amounts, so lighter formulas are a better match for those concerns.

The ingredient is produced from plant sourced stearic acid and glycerin so it is suitable for both vegans and vegetarians. No animal by products are used during manufacture.

Nothing in current safety reviews signals a problem for women who are pregnant or breastfeeding, yet this is not medical advice. Anyone expecting or nursing should show the full product label to their doctor before use to stay on the safe side.

Trihydroxymethoxystearin does not make skin more sensitive to sunlight, and it is photostable so it will not break down when exposed to light. It is also odorless and carries a low risk of interaction with active ingredients like retinol or vitamin C, making it easy to slot into most routines.

Potential Side Effects/Adverse Reactions

Reactions to the topical use of Trihydroxymethoxystearin vary from person to person. The points below list potential side effects, but they are uncommon when the ingredient is properly formulated and most users will not experience any issues.

  • Mild redness or itching in people with a specific fatty alcohol sensitivity
  • Clogged pores or breakouts if used in very rich products on acne prone skin
  • Rare allergic contact dermatitis that can cause rash or swelling
  • Transient eye irritation if an emulsion containing the ingredient gets into the eyes

If any of these effects occur stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 2 / 5

Trihydroxymethoxystearin has a fatty acid backbone similar to stearic acid, which can sit on the skin surface and potentially trap debris, yet its extra hydroxyl groups make it more water loving and less likely to form a heavy occlusive film. In most formulas it is used at modest levels where it rarely blocks pores, earning it a low-to-moderate score of 2.

People who are very prone to acne can usually use it without problems, especially in lightweight creams or makeup that contain balancing ingredients.

Formulation matters: when paired with a high load of other rich waxes or butters the overall product may feel heavier and raise the clogging risk.

Summary

Trihydroxymethoxystearin serves mainly as a skin-conditioning emollient, smoothing rough patches, filling micro gaps between skin cells and locking in water through a soft breathable film. Its modified structure raises its melting point so it stays stable in jars and sticks while still melting on contact with skin for a silky feel.

The ingredient shows up in a growing number of moisturizers, balms and high coverage foundations but it is still less common than classics like shea butter or mineral oil, making it something of a niche favorite for formulators who want richness without greasiness.

Current safety data flags no major concerns. It is generally well tolerated, vegan friendly and photostable. Even so, skin can react unpredictably to any new product so it is wise to patch test first and discontinue use if irritation occurs.

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