Triisostearin Peg-6 Esters: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Triisostearin Peg-6 Esters?

Triisostearin Peg-6 Esters is a hybrid ingredient created by reacting isostearic acid triglyceride with six units of polyethylene glycol. The result is a molecule that combines the rich, oily feel of a plant-derived triglyceride with the water-friendly nature of a short PEG chain. Originally developed to improve the texture of skincare products in the late 1990s, it quickly gained traction as brands looked for milder alternatives to traditional surfactants and mineral oils. Production begins with vegetable-sourced isostearic acid, which is converted into a triglyceride then bonded to PEG-6 through controlled esterification. The finished material is a soft, waxy solid that melts on contact with skin and disperses easily in both oil and water phases, making it popular in facial cleansers, makeup removers, sheet masks, hydrating serums, light moisturizers and leave-on hair treatments.

Triisostearin Peg-6 Esters’s Cosmetic Benefits/Uses

Formulators choose this ingredient because it delivers several helpful actions at once:

  • Skin conditioning: Forms a breathable film that leaves skin feeling soft and supple while helping to smooth rough patches
  • Emollient: Fills in microscopic gaps between skin cells, giving an immediate silky touch and preventing moisture from escaping
  • Cleansing: Its dual oil-and-water friendly structure lifts dirt, sunscreen and makeup while rinsing away without a greasy after-feel

Who Can Use Triisostearin Peg-6 Esters

This ingredient is generally compatible with most skin types, including dry, normal and combination skin, thanks to its lightweight emollient feel that softens without heavy residue. Oily or acne-prone users can usually tolerate it as well, since it rinses clean and has a low tendency to clog pores, though very blemish-prone individuals may prefer to patch test first to be sure.

Triisostearin Peg-6 Esters is made from plant-derived isostearic acid and synthetic polyethylene glycol, so it is suitable for both vegans and vegetarians. No animal-based raw materials or by-products are involved in its standard manufacturing process.

Current research shows no specific concerns for pregnant or breastfeeding women when this ingredient is used topically in cosmetics. Still, this is not medical advice and anyone who is expecting or nursing should review their skincare routine with a qualified healthcare professional before making changes.

The molecule does not increase skin’s sensitivity to sunlight, so it will not make you more prone to sunburn. It is also odorless and free of common allergens like nuts, gluten and soy, making it a low-risk choice for those with related sensitivities.

Potential Side Effects/Adverse Reactions

Side effects from topical Triisostearin Peg-6 Esters can vary from person to person. The points below highlight potential reactions, though these outcomes are uncommon when the ingredient is used correctly in a well-formulated product.

  • Mild redness
  • Temporary stinging on broken or very sensitive skin
  • Rare contact dermatitis in individuals with a specific PEG sensitivity
  • Minor eye irritation if the product accidentally gets into the eyes

If you notice persistent discomfort or any unexpected reaction, stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Triisostearin Peg-6 Esters scores a 1 out of 5 on the comedogenic scale. Its PEG portion makes the molecule water dispersible so it does not linger in pores, while the isostearin backbone is a branched fatty acid that is less likely to solidify on skin than straight chain oils. For these reasons it is generally considered safe for people who are prone to acne or breakouts. Formulas that combine it with heavy waxes or occlusive butters may raise the overall pore-clogging potential, so the full ingredient list always matters.

Summary

Triisostearin Peg-6 Esters works as a skin conditioner, emollient and gentle cleanser by marrying an oil loving triglyceride with a water friendly PEG chain. This dual nature lets it soften skin, lock in moisture and lift away grime all at once. It enjoys moderate popularity, appearing most often in modern gel cleansers, micellar waters and light lotions where a non greasy feel is essential but it is still less common than older workhorse emollients like caprylic/capric triglyceride.

Current safety data shows it is well tolerated with low irritation and low comedogenicity, making it a dependable choice for a wide range of skin types. As with any new cosmetic ingredient a simple patch test is a smart step when trying a product for the first time.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search