Tripeptide-79: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Tripeptide-79?

Tripeptide-79 is a lab-crafted chain of three amino acids designed to care for hair. Chemists build it through a step-by-step method called solid phase peptide synthesis, linking each amino acid in a controlled setting to keep the sequence pure and stable. While it does not come from plants or animals, its structure is inspired by the short protein fragments naturally found in the body. The cosmetic world began exploring small peptides in the early 2000s for their targeted action and ease of formulation, and Tripeptide-79 soon followed as brands searched for new ways to boost hair softness without heavy oils. You will most often see it in rinse-off and leave-in conditioners, strengthening shampoos, hair masks, scalp serums and styling creams that promise smoother strands.

Tripeptide-79’s Cosmetic Benefits/Uses

Tripeptide-79 appears in hair products because it acts as a hair conditioning agent. By attaching to the hair fiber it helps draw in and hold moisture, which can make strands feel softer and look shinier. Its small size lets it reach the cuticle surface more evenly than larger proteins, so it can smooth rough areas and reduce static without weighing hair down. This makes it useful in formulas aimed at improving manageability and giving a healthier look after each wash.

Who Can Use Tripeptide-79

Because it sits on the surface of hair rather than skin, Tripeptide-79 is broadly suitable for all skin types, including oily, dry and sensitive scalps. It does not clog pores or upset the skin’s moisture balance, so people prone to breakouts or flaking can usually use it without trouble. There are no known reasons it would be unsuitable for any particular skin type when found in a rinse-off or leave-in hair product.

The peptide is made entirely in a lab and contains no animal-derived material, which makes it appropriate for vegans and vegetarians. Brands that are certified cruelty-free often highlight this point.

Current safety data show no issues for pregnant or breastfeeding women when the ingredient is used in topical hair products. Still, this information is educational only, not medical advice, and anyone who is expecting or nursing should ask a doctor before adding new products to their routine.

Tripeptide-79 does not cause photosensitivity, so it will not make hair or scalp more likely to burn in the sun. It also plays well with common hair care actives like panthenol, glycerin and plant oils, so formulators can blend it without special precautions.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient can differ from person to person. The effects listed below are possible yet uncommon when Tripeptide-79 is used as directed in a finished product.

  • Mild scalp redness or warmth
  • Temporary itching or tingling
  • Contact allergy that shows up as small bumps or flaking
  • Irritation if applied to broken or already inflamed skin

If you experience any of these effects stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 0 (non-comedogenic). Tripeptide-79 is a tiny water-soluble molecule that does not contain heavy oils or waxes that could block pores, so it earns the lowest possible score. This makes it suitable for people prone to acne or breakouts. Because it is designed to sit on hair rather than penetrate facial skin, the chance of pore clogging is extremely low.

Summary

Tripeptide-79 is a lab-made chain of three amino acids that works as a hair conditioning agent. Its small size lets it attach evenly to the hair cuticle, attract moisture and smooth rough spots, which translates to softer, shinier and more manageable strands. While effective, it is still a niche ingredient that shows up mostly in higher-end conditioners, masks and serums rather than mass-market lines.

Current data point to a strong safety profile with minimal risk of irritation, allergy or pore clogging. As with any new cosmetic, doing a quick patch test before full use is a smart way to make sure your skin and scalp stay happy.

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