Trisodium Chlorin E6: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Trisodium Chlorin E6?

Trisodium Chlorin E6 is a water-soluble salt form of chlorin e6, a naturally occurring pigment related to chlorophyll that is found in certain green plants and algae. Chemically, it is a porphyrin derivative where three of its acidic groups are neutralised by sodium ions, which makes the molecule easier to dissolve in water-based formulas. Its distinct deep green colour hints at its botanical origin and light-absorbing structure.

The cosmetic world first noticed chlorin-type compounds decades ago when researchers explored plant pigments for their antioxidant and soothing qualities. Trisodium Chlorin E6 was later refined to improve stability and compatibility with skin care products. Today it is produced through a controlled extraction of plant chlorophyll followed by purification, chemical modification and neutralisation with food-grade sodium. This process yields a consistent ingredient that meets cosmetic safety standards.

Because it blends well with water, formulators can add Trisodium Chlorin E6 to a wide range of products. You may find it in calming sheet masks, hydrating gels, anti-aging serums, after-sun lotions, blemish-care spot treatments and even colour-correcting primers where its green tint can help neutralise redness.

Trisodium Chlorin E6’s Cosmetic Benefits/Uses

In skin care formulations Trisodium Chlorin E6 serves one clear purpose.

Skin conditioning: The molecule helps soften and smooth the skin by forming a light moisturising film on the surface, supporting the skin barrier and improving overall feel. Its gentle antioxidant capacity also helps protect the skin against everyday environmental stress, which can leave the complexion looking calmer and more even.

Who Can Use Trisodium Chlorin E6

Thanks to its lightweight, water-soluble nature, Trisodium Chlorin E6 generally suits all skin types from oily to dry as it conditions without leaving a heavy residue. Sensitive skin usually tolerates it well because the molecule is non-acidic and low in fragrance, though people with a history of porphyrin allergies should proceed carefully.

The ingredient is produced from plant chlorophyll and the final salt contains no animal-derived components or processing aids so it is considered suitable for vegans and vegetarians.

No data indicates specific risks for pregnant or breastfeeding women when the ingredient is used at cosmetic concentrations. This is not medical advice and anyone who is pregnant or nursing should confirm product suitability with a qualified healthcare professional.

Chlorin e6 can act as a light-absorbing photosensitiser in medical settings, but the very low amounts used in skincare and the absence of activating medical-grade light sources mean routine products are not expected to trigger photosensitivity. Standard daytime sun protection is still advised because any well-rounded routine should include SPF.

Potential Side Effects/Adverse Reactions

Responses to topical Trisodium Chlorin E6 vary by individual. The effects listed below are possible yet uncommon when the ingredient is formulated and used correctly.

  • Mild transient redness
  • Temporary tingling or warmth immediately after application
  • Allergic contact dermatitis in individuals sensitive to porphyrin compounds
  • Very slight temporary green staining if applied in high concentration without full absorption
  • Photosensitivity under intense clinical light sources such as lasers or LED therapy devices

If irritation or any unexpected reaction occurs stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Trisodium Chlorin E6 is completely water soluble and leaves no oily or waxy residue on the skin, so it does not obstruct pores or encourage the build-up of sebum and dead cells that lead to comedones. The molecule is small, rinses cleanly and is typically used at low percentages, all of which keep its pore-clogging potential essentially nil.

Because of this, the ingredient is considered suitable for people who are prone to acne or breakouts.

No data suggest it alters sebum production or interacts with common acne medications, and its green tint rinses away without settling in pores.

Summary

Trisodium Chlorin E6 is a plant-derived, water-soluble pigment that acts as a skin-conditioning agent. It forms a light moisturising film to soften and smooth skin, supplies gentle antioxidant support and lends a redness-neutralising green hue in color-correcting formulas.

The ingredient is still niche compared with mainstream hydrators like glycerin or hyaluronic acid, but formulators who want a multitasking green pigment with conditioning benefits are starting to use it more often.

Safety data show a low risk of irritation or photosensitivity at cosmetic levels, making it appropriate for most users when applied as directed. As with any new skincare product, patch testing before full-face use is a smart precaution.

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